Author Interviews, Cancer Research, Prostate, Prostate Cancer, Urology, Vaccine Studies / 08.04.2024
AACR24: Icahn Mt. Sinai Study of Autovaccination Turns Cold Prostate Cancer Cells Hot
MedicalResearch.com Interview with:
Sujit Nair, PhD
Director of GU Immunotherapy Research
Department of Urology
Icahn School of Medicine at Mount Sinai
MedicalResearch.com: What is the background for this study? How is the vaccine obtained?
Response: https://classic.clinicaltrials.gov/ct2/show/NCT03262103
Dr. Tewari is the treating physician and clinical lead on the study. This is a phase I, open-label, clinical trial (NCT03262103) using a dose escalation strategy in 12 patients diagnosed with clinically localized prostate cancer with plans for surgery. The investigational agent used in the trial is Poly-ICLC, an immune modulator developed by ONCOVIR. Poly-ICLC is a double-stranded RNA that mimics viral activity, thereby stimulating the immune response.
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