01 Feb Rosacea May Be A Marker For Autoimmune Disease
Dr. Alexander Egeberg
MedicalResearch.com Interview with:
Alexander Egeberg, MD PhD
National Allergy Research Centre, Departments of Dermato-Allergology and Cardiology
Herlev and Gentofte University Hospital
University of Copenhagen
Hellerup, Denmark
Medical Research: What is the background for this study? What are the main findings?
Dr. Egeberg: A recent genome-wide association study (GWAS) identified 90 shared genetic regions associated with celiac disease, type 1 diabetes mellitus, multiple sclerosis, and rheumatoid arthritis, respectively. Similarly, a newly published GWAS identified shared risk loci between rosacea, type 1 diabetes, and celiac disease. In the present study of 6,759 patients with rosacea and 33,795 control subjects, rosacea was associated with a 2 to 3-fold higher risk of these four conditions, particularly among women.
Medical Research: What should clinicians and patients take away from your report?
Dr. Egeberg: Rosacea may be a marker for autoimmune disease, and clinicians should focus on a personal or family history of autoimmune disease in patients with rosacea.
Medical Research: What recommendations do you have for future research as a result of this study?
Dr. Egeberg: While rosacea occurs more frequently in women, in our study we also found the most convincing associations among women, and this apparent female susceptibility should be investigated further. Moreover, since we only examined a highly selected group of autoimmune disease based on their potential genetic overlap with rosacea, future studies should look at the link between rosacea and other autoimmune conditions.
http://www.jaad.org/article/S0190-9622(15)02465-2/abstract
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Alexander Egeberg, MD PhD (2016). Rosacea May Be A Marker For Autoimmune Disease
Last Updated on February 1, 2016 by Marie Benz MD FAAD