Cardiovascular Events Decreased Most Among Adults At Highest Risk

Jay R. Desai, PhD, MPH HealthPartners Institute for Education and Research Minneapolis, MN 55425MedicalResearch.com Interview with:
Jay R. Desai, PhD, MPH

HealthPartners Institute for Education and Research
Minneapolis, MN 55425

Medical Research: What is the background for this study? What are the main findings?

Dr. Desai: SUPREME-DM is a consortium of 11 integrated health systems throughout the United States that serve a culturally and economically diverse population of 16 million members. This study monitors changes in cardiovascular outcomes from 2005 through 2011 among the 1.2 million members identified with diabetes and a matched sample of 1.2 million members without diabetes.

We found very encouraging and sustained declines in the rates of myocardial infarction/acute coronary syndrome (MI), stroke, heart failure (HF), and all-cause mortality among adults with and without diabetes.   Declines were greatest among the 15% adults who were already at high risk for cardiovascular events (such as people with diabetes or a prior history of heart disease). There was less improvement in cardiovascular event rates and mortality among the other 85% of members with low to moderate cardiovascular risk.

Medical Research: What should clinicians and patients take away from your report?

Dr. Desai: We have been making good progress in reducing rates of MI, stroke, HF, and all-cause mortality among patients already at high CV risk.  We need to extend those efforts to target lower-risk patients, and also to racial and ethnic groups that continue to have higher rates of stroke and heart failure, such as non-Hispanic blacks with diabetes.

Medical Research: What recommendations do you have for future research as a result of this study?

Dr. Desai: It will be important to continue monitoring cardiovascular event rates and mortality within U.S. health systems so that we can track improvements and identify subgroups where more tailored clinical and public health approaches may be required. Utilizing such large, real-world, electronic databases for research will provide further insight into what underlying patient, provider, and system characteristics and care practices are driving cardiovascular disease outcomes and what potential interventions can continue to improve these outcomes.  Better management of blood pressure, lipids, smoking, and other major risk factors will be needed to sustain these improvement trends.

Citation:

Who Must We Target Now to Minimize Future Cardiovascular Events and Total Mortality?: Lessons From the SUPREME-DM Cohort Study

Jay R. Desai, Gabriela Vazquez-Benitez, Zhiyuan Xu, Emily B. Schroeder,Andrew J. Karter, John F. Steiner, Gregory A. Nichols, Kristi Reynolds,Stanley Xu, Katherine Newton, Ram D. Pathak, Beth Waitzfelder, Jennifer Elston Lafata, Melissa G. Butler, H. Lester Kirchner, Abraham Thomas, andPatrick J. O’Connor

Circ Cardiovasc Qual Outcomes.2015;CIRCOUTCOMES.115.001717published online before print August 25 2015, doi:10.1161/CIRCOUTCOMES.115.001717[email protected]

[wysija_form id=”5″]

MedicalResearch.com is not a forum for the exchange of personal medical information, advice or the promotion of self-destructive behavior (e.g., eating disorders, suicide). While you may freely discuss your troubles, you should not look to the Website for information or advice on such topics. Instead, we recommend that you talk in person with a trusted medical professional.

The information on MedicalResearch.com is provided for educational purposes only, and is in no way intended to diagnose, cure, or treat any medical or other condition. Always seek the advice of your physician or other qualified health and ask your doctor any questions you may have regarding a medical condition. In addition to all other limitations and disclaimers in this agreement, service provider and its third party providers disclaim any liability or loss in connection with the content provided on this website.

MedicalResearch.com Interview with:, & Jay R. Desai, PhD, MPH (2015). Cardiovascular Events Decreased Most Among Adults At Highest Risk 

Last Updated on August 27, 2015 by Marie Benz MD FAAD