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Bruno Caramelli MD PhD Associate Professor of Medicine University of Sao Paulo, Brasil Director, Interdisciplinary Medicine in Cardiology Unit Chairman of the PhD program in Medical Sciences at the University of Sao Paulo, Brazil. President of the Department of Clinical Cardiology at the Brazilian Society of Cardiology FESC: Fellow of the European Society of Cardiology

23 Nov AHA21: GIRAF Study Results Comparing Anticoagulants and Cognitive Decline in AFib Patients

Posted at 00:24h in Alzheimer's - Dementia, Author Interviews, Clots - Coagulation, Heart Disease
GIRAF study suggests that for the preservation of cognitive function in patients with atrial fibrillation, adequate treatment is more important than the choice of the drug for anticoagulation.
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Pamela L. Lutsey, PhD Associate Professor Division of Epidemiology and Community Health University of Minnesota School of Public Health Minneapolis

26 Nov Effect of Anticoagulants Warfarin vs DOACs on Bone Health

Posted at 21:06h in Author Interviews, JAMA, Osteoporosis
This study adds to the growing body of evidence suggesting that warfarin has an adverse effect on bone health.
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Yana Vinogradova, PhD, Research Fellow Division of Primary Care, School of Medicine University of Nottingham Nottingham

07 Jul Study Finds Direct Oral AntiCoagulants (DOACs) Safe in A Fib

Posted at 12:20h in Author Interviews, BMJ, Clots - Coagulation, Heart Disease
The report provides reassurance in safety of DOACs for patients with atrial fibrillation and for patients with other indications for prescribing.
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19 May Oral Anticoagulants Still Underused in AFib Patients

Posted at 11:16h in Author Interviews, Heart Disease, JAMA, Stroke
MedicalResearch.com Interview with: Anna Gundlund,...
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28 Nov Verseon’s Precision Anticoagulants Prevent Clotting Without Excess Bleeding Risk in Preclinical Studies

Posted at 15:07h in Author Interviews, Heart Disease, Pharmaceutical Companies
MedicalResearch.com Interview with: Anirban Datta,...
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28 Jul Contraindications Not The Reason Atrial Fibrillation Patients Not Prescribed Anticoagulants

Posted at 20:51h in Author Interviews, Heart Disease
MedicalResearch.com Interview with: Tom Marshall,...
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14 Jun Patients With Paroxysmal Atrial Fibrillation Less Likely To Receive Anticoagulants

Posted at 17:46h in Author Interviews, BMJ, Heart Disease
MedicalResearch.com Interview with: Dr Nicola...
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12 Jun Head-to-Head Study Compares All Costs Associated With New Anticoagulants in Non-Valvular AFib

Posted at 18:34h in Author Interviews, Boehringer Ingelheim, Cost of Health Care, Heart Disease
MedicalResearch.com Interview with: Sabine Luik,...
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05 May After PCI, Two Anticoagulants May Be As Effective As Three

Posted at 12:05h in Author Interviews, Heart Disease, Surgical Research
MedicalResearch.com Interview with: Nayan Agarwal...
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04 May Anticoagulants Remove Excess Stroke Risk Posed By Atrial Fibrillation

Posted at 15:09h in Author Interviews, Heart Disease, JAMA, Stroke
MedicalResearch.com Interview with: Dr. Ben Freedman...
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20 Jan History of Bleeding Helps Predict Risk of Bleeding from Anticoagulants

Posted at 02:44h in Author Interviews, Heart Disease
More on Anticoagulants on MedicalResearch.com...
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07 Jan Study Finds Women Who Take Anticoagulants Can Use Hormonal Therapy

Posted at 22:17h in Author Interviews, Blood Clots, Endocrinology, Hormone Therapy, Pharmacology
MedicalResearch.com Interview with: Ida Martinelli...
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Juan Jesus Carrero Pharm PhD Professor of Epidemiology Cardio-renal Department of Medical Epidemiology and Biostatistics Karolinska Institutet, Stockholm

06 Oct Study Finds Reduced Kidney Disease Progression with DOACs vs Vitamin K Antagonists

Posted at 10:16h in Author Interviews, Clots - Coagulation, Heart Disease, Karolinski Institute, Kidney Disease
These findings add to emerging evidence on the safety and effectiveness of DOAC administered for atrial fibrillation. 
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pills medications

06 Oct Number of Emergency Room Visits for Medication Harms Increases with Age

Posted at 17:49h in Author Interviews, CDC, Emergency Care, JAMA
Among patients 45 years of age and older, therapeutic use of anticoagulants (blood thinners) and diabetes medications were the most common causes of ED visits for medication-related harms.
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Atrial Fibrillation Wikipedia example

30 Sep Risk of Stroke Acutely Elevated by Episodes of Paroxysmal Atrial Fibrillation

Posted at 22:12h in Author Interviews, Brigham & Women's - Harvard, Heart Disease, JAMA, Stroke
From a mechanistic point of view, atrial fibrillation appears to be a cause of stroke, not just a marker of other causes of ischemic stroke.
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Manish M Sood MD FRCPC MSc Jindal Research Chair for the Prevention of Kidney Disease Associate Professor of Medicine, Dept. of Medicine and the School of Epidemiology and Public Health University of Ottawa Scientist, Ottawa Hospital Research Institute  Nephrologist, The Ottawa Hospital Ottawa, Ontario, Canada

09 Jun Increased Bleeding Risk with Clarithromycin-DOAC Anticoagulant Regimen

Posted at 00:37h in Author Interviews, Clots - Coagulation, JAMA, Kidney Disease
Early work has suggested a very commonly used antibiotic, clarithromycin, may interfere with the metabolism of the most widely used type of blood thinning medication (called direct oral anticoagulants or DOACs) such that the blood level of the DOAC increases and may place the patient at a higher risk for bleeding
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Marta Cortes Canteli, PhD Miguel Servet Research Fellow Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) Madrid, Spain

09 Oct Long Term Treatment With Dabigatran Reduces Alzheimer’s Symptoms in Mouse Model

Posted at 16:42h in Alzheimer's - Dementia, Author Interviews, Clots - Coagulation
Long-term treatment with an oral direct anticoagulant ameliorates Alzheimer´s disease pathogenesis in a mouse model of the disease.
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Sunil Badve MBBS, MD, DNB, FRACP, PhD, FASN Senior Research Fellow, Renal & Metabolic Division Staff specialist nephrologist | St George Hospital University of New South Wales The George Institute for Global Health Australia

16 Jul Oral Anticoagulant in Chronic Kidney Disease: Benefits and Harms

Posted at 19:29h in Annals Internal Medicine, Author Interviews, Clots - Coagulation, Heart Disease, Kidney Stones
There is insufficient evidence to conclude whether patients with advanced stages of CKD or ESKD derive benefit from VKA or NOAC.
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Renato D. Lopes MD, MHS, PhD Duke University Medical Center Duke Clinical Research Institute Durham, NC 27705

21 Mar Atrial Fibrillation: Antithrombotic Therapy after Acute Coronary Syndrome or PCI

Posted at 23:38h in Author Interviews, Clots - Coagulation, Duke, Heart Disease, NEJM
 For the majority of patients, if you look at the totality of data, one lesion learned that is now confirmed by AUGUSTUS is that less is more
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Stavros V. Konstantinides, MD, PhD, FESC, FRCP(Glasg)Professor, Clinical Trials, and Medical DirectorCenter for Thrombosis and Hemostasis (CTH)Johannes Gutenberg University MainzMainz, Germany

18 Mar Home Treatment of Patients with Low-Risk Pulmonary Embolism

Posted at 13:19h in Author Interviews, Clots - Coagulation, Heart Disease
Early discharge with continuation of oral anticoagulant treatment at home is effective and safe in patients with acute low-risk PE identified by simple clinical criteria and the absence of RV dysfunction on admission
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Geoffrey Barnes, MD, MScAssistant ProfessorVascular and Cardiovascular MedicineUniversity of Michigan

05 Mar Many Patients Taking Warfarin Plus Aspirin Without Clear Indication

Posted at 13:35h in Author Interviews, Clots - Coagulation, Heart Disease, JAMA
Many patients who take oral anticoagulants (such as warfarin) may also be taking aspirin without any clear indication.
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Alex C Spyropoulos, MD, FACP, FCCP, FRCPC Professor of Medicine – The Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Professor - The Center for Health Innovations and Outcomes Research - The Feinstein Institute for Medical Research System Director – Anticoagulation and Clinical Thrombosis Services Northwell Health at Lenox Hill Hospital New York, NY 10075

04 Oct NEJM: Rivaroxaban (XARELTO®) For Thromboembolism Prevention after Medical Illness

Posted at 12:36h in Author Interviews, Clots - Coagulation, Critical Care - Intensive Care - ICUs, NEJM
MedicalResearch.com Interview with: Alex C...
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John D Horowitz, MBBS, PhD. Director of Cardiology/Clinical Pharmacology Queen Elizabeth Hospital University of Adelaide Australia

09 Aug New Biomarkers Predictive of Atrial Fibrillation Outcome

Posted at 01:15h in Author Interviews, Biomarkers, Heart Disease, JACC
MedicalResearch.com Interview with: John D...
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22 Feb Aspirin or Rivaroxaban for VTE Prophylaxis after Hip or Knee Arthroplasty?

Posted at 12:14h in Author Interviews, Hematology, NEJM, Orthopedics, Thromboembolism
MedicalResearch.com Interview with: Dr. David...
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13 Feb Some Heart Attack Patients Without AFib Still at Increased Risk of Stroke

Posted at 13:42h in Author Interviews, Heart Disease, JACC, Stroke
MedicalResearch.com Interview with: João Pedro...
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07 Feb Real World Studies Compares Dabigatran with Rivaroxaban or Apixaban in Nonvalvular AFib

Posted at 22:48h in AHA Journals, Author Interviews, Stroke
MedicalResearch.com Interview with: Todd C....
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26 Jan Could NOACs Be Better Option Than Warfarin To Prevent Ischemic Stroke?

Posted at 12:59h in Author Interviews, JAMA, Stroke
MedicalResearch.com Interview with: Taku Inohara...
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13 Jan Feasibility of Anticoagulating Cancer Patients At Increased Risk of Stroke

Posted at 20:54h in Author Interviews, Cancer Research, JAMA, Stroke
MedicalResearch.com Interview with: Babak B....
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16 Dec Breakthrough Treatment With Prometic’s IV Plasminogen Treats Rare Disabling Disorder

Posted at 01:34h in Author Interviews, Hematology
MedicalResearch.com Interview with: Dr. Charles T....
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21 Nov NOACs For Atrial Fib Anticoagulation May Have Lower Risk of Kidney Side Effects

Posted at 02:06h in Author Interviews, Heart Disease, JACC, Kidney Disease, Mayo Clinic
Interview with: Dr Xiaoxi Yao...
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