22 Oct Cannabis Improved Symptoms, but Not Inflammation of Crohn’s Disease
MedicalResearch.com Interview with:
Timna Naftali MD
Specialist in Gastroenterology
Meir Hospital and Kupat Holim Clinic,
Tel Aviv University, Israel
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: In previous studies we could see that Crohn’s patients improve symptoms when taking cannabis but we did not have good data about actual inflammation.
So, in this study we added a colonoscopy to see if we can detect any change in inflammation. We also wanted to find a better mode of consuming cannabis, other than smoking.
MedicalResearch.com: What should readers take away from your report?
Response: The take home massage would be that cannabis may help the patients feel better, but is not a replacement of conventional medical therapy. It should be used as an adjuvant to other treatments in appropriate cases.
MedicalResearch.com: What recommendations do you have for future research as a result of this work?
Response: Regarding future research, there are many points that should be addressed:
- Cannabis in laboratory trials does have an anti-inflammatory effect. We have to find a way of translating this effect to clinical treatment
- What is the best way of administering cannabis? (We certainly do not want to recommend smoking)
- What is the best dose/combination?
- What are the long term effects?
- Which patients, if any, will benefit most?
UEG 2018 abstract:
Cannabis induces clinical response but no endoscopic response in Crohn’s disease patients
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