Hot Sun Increases Absorption of Sunscreen Ingredients

MedicalResearch.com Interview with:
Audra Stinchcomb, PhD

Principal Investigator
Professor of Pharmaceutical Sciences
University of Maryland School of Pharmacy

MedicalResearch.com: What is the background for this study?  

Response: We have been studying the heat effects and repeated dose effects on the absorption of drugs across the skin for more than 5 years.  We were curious to see if the effects we saw on gel, cream, and ointment pharmaceuticals also occurred with sunscreen.

Sunscreens are typically used in the hot sun and with reapplication every 80 minutes or so, depending on the product and user.

MedicalResearch.com: What are the main findings?

Response: The main findings in our laboratory human skin model showed that a temperature similar to direct sun exposure significantly increased the absorption of a common active ingredient in sunscreens, as compared to typical room temperature.

We also saw that the type of product we used influenced the laboratory-based skin absorption of this sunscreen ingredient.  Additionally, frequent reapplication of some products resulted in increased absorption, as compared to a single application.

MedicalResearch.com: What should readers take away from your report?

Response: Sunscreen use is safe and absolutely necessary, but it may be a good idea to test future sunscreen products in a different way than currently used, if similar results to our laboratory studies are seen in people. 

MedicalResearch.com: What recommendations do you have for future research as a result of this study?

Response: We will do a healthy human volunteer study to confirm these laboratory results.

 No disclosures 

Citation:

Evaluation of Reapplication and Controlled Heat Exposure on Oxybenzone Permeation from  Commercial Sunscreen Using Excised Human Abdominal Skin
2018 American Association of Pharmaceutical Scientists (AAPS) PharmSci 360 Meeting

Nov 15, 2018 @ 8:55 pm

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