MedicalResearch.com Interview with:
Eric Huang, PhD
Professor, Department of Dermatology
University of California, San Diego
MedicalResearch.com: What is the background for this study? To whom would the vaccine be targeted? Affected individuals? Patients with strong family history? Resistant acne cases?
Response: The background for this study is to develop vaccines to replace the antibiotics which may induce resistant bacteria.
Preventive acne vaccines will be used for injection into elementary students to prevent the acne development when they become teenagers. Therapeutic acne vaccines using monoclonal antibodies will be used for those patients who already have acne vulgaris.
Both patients with strong family history and resistant acne cases are highly recommended to use when the acne vaccines are available.
MedicalResearch.com: What are the main findings?
Response: Propionibacterium acnes (P. acnes), now called Cutibacterium acnes (C. acnes). bacteria have associated with the progress of acne vulgaris. Vaccines targeting the virulence factors secreted from P. acnes significantly reduce the inflammation.
MedicalResearch.com: What should readers take away from your report?
Response: Vaccination may be a new method for treatment of acne vulgaris.
MedicalResearch.com: What recommendations do you have for future research as a result of this work?
Response: Clinical trials should be conducted shortly to validate the efficacy of acne vaccines in humans.
MedicalResearch.com: Is there anything else you would like to add?
Response: Acne vaccines will release many suffers from acne patients. In the past years, I almost received emails every day from acne suffers. They would like to become volunteers for clinical trials and are looking forward to having this vaccine in the market soon.
Citation: Yanhan Wang, Tissa R. Hata, Yun Larry Tong, Ming-Shan Kao, Christos C. Zouboulis, Richard L. Gallo, Chun-Ming Huang. The Anti-Inflammatory Activities of Propionibacterium acnes CAMP Factor-Targeted Acne Vaccines. Journal of Investigative Dermatology, 2018; DOI: 10.1016/j.jid.2018.05.032
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