27 Aug Lupus Nephritis Susceptibility Genes Identified

Posted at 12:37h in Author Interviews, Kidney Disease, Rheumatology by

Hemodialysis.com Interview with:

Dr. David W. Powell PhD
Associate Director of Clinical Proteomics
Assistant Professor of Medicine Assistant
Professor of Biochemistry and Molecular Biology
Department of Medicine/Nephrology
570 South Preston Street Baxter Research Building I, Room 102 South
Louisville, Kentucky

Hemodialysis.com: What are the main findings of the study? 

Dr. Powell: We found a strong association for variants in the gene encoding ABIN1 (a physiologic inhibitor of NF-B) and nephritis in systemic lupus erythematosus patients and that mice expressing a loss of function mutation of ABIN1 develop pathophysiologic features of the most common and severe form of human lupus nephritis.

Please read the rest on Hemodialysis.com.

 

Last Updated on August 27, 2013 by Marie Benz MD FAAD

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