22 Nov Seasonal Changes in Thyroid Function Tests
MedicalResearch.com Interview with:
Charit Taneja, MBBS
Internal Medicine Resident
Maria Brito, MD
Co-Director, Mount Sinai’s Thyroid Center
Assistant Professor, Medicine, Endocrinology, Diabetes and Bone Disease
Icahn School of Medicine at Mount Sinai
MedicalResearch.com: What is the background for this study?
Response: There have been reports of seasonal fluctuations in thyroid function, however there are no standard guidelines for management of such fluctuations and their clinical implications. It is not a well-studied subject and there are insufficient guidelines around its clinical implications.
MedicalResearch.com: What are the main findings?
Response: Our patient had winter elevation of TSH and summer normalisation repeatedly over a course of three years, but remained largely asymptomatic despite the biochemical alterations.
MedicalResearch.com: What should readers take away from your report?
- Seasonal changes can occur in TSH, and would become clinically important in the following scenarios: pregnancy, postpartum, and in patients that are symptomatic from thyroid dysfunction.
- So long as the abnormality is mild, patients with asymptomatic fluctuations in thyroid function don’t necessarily require treatment with levothyroxine, given the cyclical normalization.
MedicalResearch.com: What recommendations do you have for future research as a result of this work?
Response: Ours was a case study from a single patient. We are looking for patients with similar variations to study thyroid function trends and their clinical implications in a larger group. Widespread use of thyroid function testing in asymptomatic individuals could possibly result in greater detection of such cases.
We have no disclosures.
SEASONAL TRANSITIONS BETWEEN EUTHYROIDISM AND SUBCLINICAL HYPOTHYROIDISM
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