27 Jan Rosacea Linked To Slight Increased Risk of Glioma
MedicalResearch.com Interview with:
Alexander Egeberg, MD PhD
National Allergy Research Centre, Departments of Dermato-Allergology and Cardiology
Herlev and Gentofte University Hospital
University of Copenhagen
Medical Research: What is the background for this study? What are the main findings?
Dr. Egeberg: There appears to be an overlap in the pathogenesis of rosacea and glioma, focused around matrix metalloproteinases.
Rosacea may be associated with an increased risk of glioma, however, it is important to note that the absolute risk is still low. Whether this is a causal link is not known.
Medical Research: What should clinicians and patients take away from your report?
Dr. Egeberg: Clinicians and patients should keep in mind that the absolute risk of glioma is still low, even in patients with rosacea. However, if patients develop neurological symptoms (such as headaches, memory loss, seizures, loss of muscle control, visual symptoms, dysarthria, cognitive decline, and personality changes) referral to relevant specialists may be appropriate.
Medical Research: What recommendations do you have for future research as a result of this study?
Dr. Egeberg: A subgroup of patients with rosacea have so-called ‘neurogenic rosacea’, with prominent neurological symptoms such as burning and stinging pain from the skin, migraine, and neuropsychiatric symptoms. This could suggest a link between rosacea and neurological diseases, an research in this area is warranted.
Egeberg A, Hansen PR, Gislason GH, Thyssen JP. Association of Rosacea With Risk for Glioma in a Danish Nationwide Cohort Study. JAMA Dermatol. Published online January 27, 2016. doi:10.1001/jamadermatol.2015.5549.
Dr. Alexander Egeberg (2016). Rosacea Linked To Slight Increased Risk of Glioma