Study Finds No Link Between Calcium Channel Blockers and Breast Cancer

MedicalResearch.com Interview with:
Dr. Gudrun Jonasdottir Bergman PhD
National Board of Health and Welfare
Sweden, Stockholm, Sweden

Medical Research: What are the main findings of this study? 

Dr. Gudrun Jonasdottir Bergman: A recent study by Li et al [1] showed that long term use of Calcium Channel Blockers (CCB) increases the risk of developing breast cancer. We replicated a study by Li et al [2] by using population based registries with high over coverage.

The results showed that 5 years exposure to Calcium Channel Blockers did not significantly increase the odds of developing breast cancer (OR=1.1), which is similar to the effect after 5-9.9 years in the study by Li et al [2].

However, since the use of Calcium Channel Blockers is increasing and since Li et al [2] showed that long term use (> 10 years) of Calcium Channel Blockers may increase the odds of developing breast cancer, the Swedish National Board of Health and Welfare has the intention to continuously follow breast cancer incidence in relation to usage of Calcium Channel Blockers.

Citation:

Breast Cancer Risk and Use of Calcium Channel Blockers Using Swedish Population Registries

Bergman G, Khan S, Danielsson B, Borg N. Breast Cancer Risk and Use of Calcium Channel Blockers Using Swedish Population Registries. JAMA Intern Med. Published online August 18, 2014. doi:10.1001/jamainternmed.2014.3867.