28 Jun Fish Intake and Risk of Breast Cancer
MedicalResearch.com Interview with Duo Li (PhD, MSc, BMed)
Co-Editor, Asia Pacific Journal of Clinical Nutrition
Associate Editor, Journal of Nutrigenetics & Nutrigenomics
Professor of Nutrition
Dept. of Food Science & Nutrition
866 Yu-Hang-Tang Road
Hangzhou 310058, China
MedicalResearch.com: What are the main findings of the study?
Dr. Li: The main finding is that intake marine n-3 polyunsaturated fatty acids (n-3 PUFAs) from both fish and fish oil lower the risk of breast cancer. Women with a high intake of marine n-3 PUFAs had a 14-percent reduction in risk of breast cancer compared with those who had a low intake. Every 0.1 g increase in marine n-3 PUFA per day was linked to a five-percent reduction in breast cancer risk.
MedicalResearch.com: Were any of the findings unexpected?
Dr. Li: Yes, lower fish intake and Alpha-linolenic acid ( ALA , a plant omega-3 PUFA) are not significantly associated with decreased breast cancer risk.
MedicalResearch.com: What should clinicians and patients take away from your report?
Dr. Li: For no fish eaters, we suggest woman who should intake fish oil one gram per day. For lower fish eaters, increment of oily fish such as salmon, tuna or sardines should be 1-2 portions per person per week.
MedicalResearch.com: What recommendations do you have for future research as a result of this study?
Dr. Li: The protective effect of fish or individual n-3 PUFA warrants further investigation of prospective studies. Mechanism of marine n-3 PUFAs decrease the risk of breast cancer need to be explored in the future.
Intake of fish and marine n-3 polyunsaturated fatty acids and risk of breast cancer: meta-analysis of data from 21 independent prospective cohort studies:
Zheng J ,Hu X ,Zhao Y ,Yang J ,Li D. Intake of fish and marine n-3 polyunsaturated fatty acids and risk of breast cancer: meta-analysis of data from 21 independent prospective cohort studies. BMJ 2013;346:f3706