GERD Associated With Increased Risk of Malignancy of the Upper Aerodigestive Tract

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https://medicalresearch.com/cancer-_-oncology/gerd-associated-with-increased-risk-of-malignancy-of-the-upper-aerodigestive-tract/39049/

MedicalResearch.com Interview with:

Dr. Edward D. McCoul, MD, MPH Ochsner Medical Center

Dr. McCoul

Dr. Edward D. McCoul, MD, MPH
Ochsner Medical Center

MedicalResearch.com: What is the background for this study? What are the main findings?

Response: Population-level data suggests a link between gastroesophageal reflux disease and cancer of the throat and sinuses in adults over 65 years of age.  T

he strength of association between reflux and cancer is strongest for anatomic sites closest to the esophagus, where acid and other stomach contents may have the greatest exposure.

MedicalResearch.com: What should clinicians and patients take away from your report?

Response: It is important to point out that a causative link cannot be established from this type of data.

It is unclear what effect acid exposure may have on tumor development, although chronic inflammation is a possibility.

MedicalResearch.com: What recommendations do you have for future research as a result of this study?

Response: Further research should focus on assessing these associations in a younger population and investigating mechanisms of causation.

MedicalResearch.com: Thank you for your contribution to the MedicalResearch.com community.

Citation:

Charles A. Riley, Eric L. Wu, Mei-Chin Hsieh, Michael J. Marino, Xiao-Cheng Wu, Edward D. McCoul. Association of Gastroesophageal Reflux With Malignancy of the Upper Aerodigestive Tract in Elderly Patients. JAMA Otolaryngol Head Neck Surg. Published online December 21, 2017. doi:10.1001/jamaoto.2017.2561

Note: Content is Not intended as medical advice. Please consult your health care provider regarding your specific medical condition and questions.

 

 

 

 

 

 

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