Surgical Castration Linked To Fewer Side Effects Than Androgen Deprivation in Prostate Cancer

Quoc-Dien Trinh MD Assistant Professor, Harvard Medical School Brigham and Williams Hospital

Dr. Trinh

MedicalResearch.com Interview with:
Quoc-Dien Trinh MD

Assistant Professor, Harvard Medical School
Brigham and Williams Hospital 

Medical Research: What is the background for this study? What are the main findings?

Dr. Trinh: Among elderly Medicare beneficiaries with metastatic prostate cancer, surgical castration is associated with lower risks of any fractures, peripheral arterial disease, and cardiac-related complications compared to medical castration using GnRH agonists.

Medical Research: What recommendations do you have for future research as a result of this study?

Dr. Trinh: I find it disconcerting that a perfectly reasonable, cost-effective surgical treatment with potentially less adverse effects and compliance issues than its pharmacologic equivalent has disappeared from medical practice for non-scientific reasons.

Citation:

Maxine Sun, Toni K. Choueiri, Ole-Petter R. Hamnvik, Mark A. Preston, Guillermo De Velasco, Wei Jiang, Stacy Loeb, Paul L. Nguyen, Quoc-Dien Trinh. Comparison of Gonadotropin-Releasing Hormone Agonists and Orchiectomy.

JAMA Oncology, 2015; 1 DOI:10.1001/jamaoncol.2015.4917

Quoc-Dien Trinh MD (2016). Surgical Castration Linked To Fewer Side Effects Than Androgen Deprivation in Prostate Cancer

One thought on “Surgical Castration Linked To Fewer Side Effects Than Androgen Deprivation in Prostate Cancer

  1. This is good news that there are better treatment for prostate cancer with lower adverse side effects. This will be good news for men with prostate cancer.

Leave a Reply

Your email address will not be published.

This site uses Akismet to reduce spam. Learn how your comment data is processed.