CHD Risk Increases in Diabetes with Aggressive Blood Pressure Control

MedicalResearch.com Interview Invitation Dr. Gang Hu, MD, PHD

Pennington Biomedical Research Center, Baton Rouge, Louisiana

MedicalResearch.com: What are the main findings of the study?

Dr. Gang Hu: There is a U-shaped or inverse association between BP and the risk of CHD, and aggressive BP control (BP<120/70 mmHg) is associated with an increased risk of CHD among both African American and white patients with diabetes.

MedicalResearch.com: Were any of the findings unexpected?

Dr. Gang Hu:  Uncontrolled BP increased risk of CHD is what’s expected, while aggressive BP control can increased risk of CHD may be somewhat unexpected.

MedicalResearch.com: What should clinicians and patients take away from your report?

Dr. Gang Hu:  We should pay attention not only to the harm of uncontrolled blood pressure but the aggressively controlled blood pressure.

MedicalResearch.com: What recommendations do you have for future research as a result of this study?

Dr. Gang Hu:  Further study is needed about other macrovascular disease outcome, such as heart failure, stroke, amputation.
Citation:

Aggressive Blood Pressure Control Increases Coronary Heart Disease Risk Among Diabetic Patients

Wenhui Zhao, Peter T. Katzmarzyk, Ronald Horswell, Yujie Wang, Wei Li, Jolene Johnson, Steven B. Heymsfield, William T. Cefalu, Donna H. Ryan, and Gang Hu

Aggressive Blood Pressure Control Increases Coronary Heart Disease Risk Among Diabetic Patients Diabetes Care published ahead of print May 20, 2013, doi:10.2337/dc13-0189

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