Dual Hormone Artificial Pancreas Reduces Nocturnal Hypoglycemia in Type 1 Diabetes

MedicalResearch.com Interview with:
Dr Ahmad Haidar Ph.D. Division of Experimental Medicine Department of Medicine, McGill University Montreal, QC, CanadaDr. Ahmad Haidar Ph.D
Division of Experimental Medicine, Department of Medicine
McGill University, Montreal, QC, Canada

Medical Research: What is the background for this study? What are the main findings?

Dr. Haidar: This is the first head-to-head-to-head comparison in outpatient setting of dual-hormone artificial pancreas, single-hormone artificial pancreas, and conventional pump therapy in children and adolescents with type 1 diabetes.

The main finding is that the dual-hormone artificial pancreas seems to outperform the other two systems in reducing nocturnal hypoglycemia in camp settings when the patients are very physically active during the day.

Medical Research: What should clinicians and patients take away from your report?

Dr. Haidar: Glucagon has the potential to reduce nocturnal hypoglycemia if added to the artificial pancreas. However, this needs to be confirmed in larger and longer studies as the single-hormone artificial pancreas might be sufficient in home settings (this study was conducted at a camp, which is an environment different that home).

Medical Research: What recommendations do you have for future research as a result of this study?

Dr. Haidar: We need to conduct longer and larger day-and-night outpatient studies (our study was for only 3 nights per intervention).

Citation:

Outpatient overnight glucose control with dual-hormone artificial pancreas, single-hormone artificial pancreas, or conventional insulin pump therapy in children and adolescents with type 1 diabetes: an open-label, randomised controlled trial

 DOI: http://dx.doi.org/10.1016/S2213-8587(15)00141-2

 

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Dr. Ahmad Haidar Ph.D, Division of Experimental Medicine, Department of Medicine, & McGill University, Montreal, QC, Canada (2015). Dual Hormone Artificial Pancreas Reduces Nocturnal Hypoglycemia in Type 1 Diabetes 

Last Updated on June 13, 2015 by Marie Benz MD FAAD