Hormone Combination Effective For Male Contraception But With Many Side Effects

MedicalResearch.com Interview with:
Mario Philip Reyes Festin, MD

World Health Organization
Geneva, Switzerland. 

MedicalResearch.com: What is the background for this study?

Response: Researchers are trying to identify a hormonal male contraceptive that is effective, reversible, safe, acceptable, affordable, and available. Most of the research has been done either by groups of university researchers. However, in the 1990s, WHO undertook two multi-center, multinational studies.

The studies were unable to provide evidence to support the development of a commercially viable, and user-acceptable product.

MedicalResearch.com: What are the main findings?

Response: This study found that the hormone combination described was able to provide contraceptive protection, but there were many side effects.

MedicalResearch.com: What should readers take away from your report?What recommendations do you have for future research as a result of this study?

Response: WHO has issued no guidance on hormonal male contraceptives. The Organization currently recommends two male centered contraceptive methods – male condoms and vasectomy.

A WHO researcher has been involved in the new study published by the Endocrine Society, but much more research will be required before the Organization will be in a position to comment.

MedicalResearch.com: Is there anything else you would like to add?

Response: For more information on contraceptives please see the following fact sheet: http://www.who.int/mediacentre/factsheets/fs351/en/

MedicalResearch.com: Thank you for your contribution to the MedicalResearch.com community.


Hermann M. Behre, Michael Zitzmann, Richard A. Anderson, David J. Handelsman, Silvia W. Lestari, Robert I. McLachlan, M. Cristina Meriggiola, Man Mohan Misro, Gabriela Noe, Frederick C. W. Wu, Mario Philip R. Festin, Ndema A. Habib, Kirsten M. Vogelsong, Marianne M. Callahan, Kim A. Linton, and Doug S. Colvard.
Efficacy and Safety of an Injectable Combination Hormonal Contraceptive for MenJournal of Clinical Endocrinology & Metabolism, October 27, 2016 DOI: 10.1210/jc.2016-2141

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Last Updated on October 29, 2016 by Marie Benz MD FAAD