MedicalResearch.com Interview with:
Darwin Chen, MD
Assistant Professor, Orthopaedics
Icahn School of Medicine at Mount Sinai
MedicalResearch.com: What is the background for this study?
Response: Total hip and knee replacement surgery are among the most commonly performed orthopaedic procedures today. Although success rates are high, complications can occur and some may be preventable. The goal of our research was to assess the impact of gender on complications within the first 30 days after hip and knee replacement.
MedicalResearch.com: What are the main findings?
Response: We looked at a large national database (NSQIP) and assessed 54,502 patients undergoing THA and 87,177 patients undergoing TKA. After both hip and knee replacement, female gender was found to be protective of mortality, sepsis, cardiovascular events, unplanned reintubation, and renal complications. Female gender was an independent risk factor for urinary tract infections, needing a blood transfusion, and discharge to a rehabilitation facility.
MedicalResearch.com: What should readers take away from your report?
Response: Males and females have different postoperative risks for unclear reasons. Some theories include differences in preoperative hemoglobin levels, home support systems, pain tolerance, and other comorbid medical conditions.
MedicalResearch.com: What recommendations do you have for future research as a result of this study?
Response: The postsurgical risks after hip and knee replacement are different between men and women. When we counsel our patients before surgery, gender should play a role in the discussion.
MedicalResearch.com: Thank you for your contribution to the MedicalResearch.com community.
Citation: Abstract presented at the AAOS 2017 meeting
Influence of Gender on Outcomes after Primary Joint Replacement Darwin D. Chen, MD, New York, NY Jonathan Robinson, MD, New York, NY John I. Shin, BS, New York, NY The study is a comprehensive analysis of patients undergoing THA and TKA based on gender and reveals the impact of gender on adverse postoperative events.http://newsroom.aaos.org/media-resources/Annual-Meeting
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