Overactive Bladder: Use of Antimuscarinics

MedicalResearch.com Interview with:

Kirill Kosilov
Far Eastern Federal University
Department of Neurourology-Urodynamics, Primorsky Regional Diagnostic Center, Vladivostok, Russian Federation

MedicalResearch.com What are the main findings of the study?

Answer: Our study in a group of elderly patients showed that the combination of antimuscarinic drugs in a dosage which is higher than the usual recommended one is an effective treatment option for patients with OAB in those cases where treatment with one antimuscarinic drug was poorly effective. Side effects occurred almost equally in patients treated with only one antimuscarinic drug compared to the combined dosage.

MedicalResearch.com Were any of the findings unexpected?

Answer: All the main results of our work have been widely anticipated.

MedicalResearch.com: What should clinicians and patients take away from your report?

Answer: In most cases, urinary incontinence associated with neurogenic overactive bladder well managed with high doses of antimuscarinic drugs without increasing the risk of side effects.

MedicalResearch.com: What recommendations do you have for future research as a result of this study?

Answer: In subsequent studies, we hope to compare the different forms of securing and retaining a good effect on the lead with high doses of antimuscarinic treatment in elderly patients


Management of Overactive Bladder (OAB) in Elderly Men and Women with Combined, High-Dosed Antimuscarinics without Increased Side Effects

UroToday Int J. 2013 August;6(4):art 47. http://dx.doi.org/10.3834/uij.1944-5784.2013.08.06