MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Recent evidence suggests that the DASH diet is associated with lower uric acid levels and lower risk of gout. Furthermore, a secondary analysis of the DASH trial showed that complete replacement of a typical American diet with the DASH diet lowered uric acid levels. However, it is unknown if partial replacement of a typical American diet with DASH foods might lower uric acid.
MedicalResearch.com: What should readers take away from your report?
Response: We found that in the overall group of African Americans with hypertension from an urban clinic, partial replacement of a typical American diet with DASH foods at an amount of $30/week did not affect uric acid levels. However, the results varied by participants’ uric acid levels at the start of the trial such that people with higher baseline uric acid levels had significantly greater reductions in uric acid. While these findings suggest that $30/week may not be adequate to achieve uric acid reduction in all participants of our study, it may be enough to cause significant reductions in those with hyperuricemia.
MedicalResearch.com: What recommendations do you have for future research as a result of this work?
Response: Future research should examine more comprehensive replacement of home foods with DASH foods. Furthermore, future studies should target participants with hyperuricemia.
Stephen P Juraschek, MD, PhD,1 Allan C Gelber, MD, PhD,1 Hyon K Choi, MD, DrPH,2 Lawrence J Appel, MD, MPH,1 and Edgar R Miller, III, MD, PhD1
Arthritis Rheumatol. 2016 Dec; 68(12): 3002–3009.
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