atrial-fibrillation

Atrial Fibrillation and Alcohol Abstinence

MedicalResearch.com Interview with:

Professor Peter M Kistler MBBS, PhD, FRACP Head of Clinical Electrophysiology Research Baker Heart and Diabetes Institute Head of Electrophysiology at The Alfred hospital Professor of Medicine University of Melbourne.

Dr. Kistler

Professor Peter M Kistler MBBS, PhD, FRACP
Head of Clinical Electrophysiology Research
Baker Heart and Diabetes Institute
Head of Electrophysiology at The Alfred hospital
Professor of Medicine
University of Melbourne.

MedicalResearch.com: What is the background for this study?

Response: There is a well known association between alcohol intake and atrial fibrillation form population based studies which demonstrate that for every 1 standard drink the incidence of AFib increases by 8%.

This is the first randomised study to determine of alcohol reduction/abstinence leads to a reduction in AFib episodes and time to recurrence.

MedicalResearch.com: What are the main findings?

Response: The study showed that in patients with recurrent episodes of atrial fibrillation who consumed moderate quantities of alcohol (average of 16 standard drinks per week), significantly cutting down their alcohol intake or abstaining altogether delayed the onset of their next AF episode and reduced the proportion of time spent in atrial fibrillation.

MedicalResearch.com: What should readers take away from your report?

Response: If you have atrial fibrillation and consume more than 10 standard drinks per week you should ideally abstain from alcohol or reduce consumption substantially to determine the impact of this intervention on your episodes and symptoms. This is a much safer and potentially effective strategy with the alternatives being medication and/or catheter ablation. People who abstained from alcohol also saw significant reductions in weight and blood pressure.

MedicalResearch.com: What recommendations do you have for future research as a result of this work?

Response: Ideally a larger study although recruitment was difficult with many patients unwilling to potentially abstain from alcohol.

There were no disclosures.

Citation:

Alcohol Abstinence in Drinkers with Atrial Fibrillation

Aleksandr Voskoboinik, M.B., B.S., Ph.D., Jonathan M. Kalman, M.B., B.S., Ph.D., Anurika De Silva, Ph.D., Thomas Nicholls, M.B., B.S., Benedict Costello, M.B., B.S., Shane Nanayakkara, M.B., B.S., Sandeep Prabhu, M.B., B.S., Ph.D., Dion Stub, M.B., B.S., Ph.D., Sonia Azzopardi, R.N., Donna Vizi, R.N., Geoffrey Wong, M.B., B.S., Chrishan Nalliah, M.B., B.S., 

N Engl J Med 2020; 382:20-28
DOI: 10.1056/NEJMoa1817591

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Last Modified: Jan 2, 2020 @ 12:20 pm

 

 

 NEJM Alcohol Abstinence in Drinkers with Atrial Fibrillation

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