Frequent PVCs: Catheter Ablation Improved Left Ventricular Function

Professor Ben He Department of Cardiology Renji Hospital, School of Medicine Shanghai Jiao Tong University, Shanghai China.MedicalResearch.com Interview with:
Professor Ben He
Department of Cardiology
Renji Hospital, School of Medicine
Shanghai Jiao Tong University, Shanghai China.


MedicalResearch.com: What are the main findings of the study?

Professor He: Elimination of PVCs by catheter ablation can improve LVEF and reverse LV dimensions. The pooled mean change in LVEF post-ablation meets the prespecified borderline (5%) and can be considered clinically effective. Beneficial effects of ablation of frequent PVCs in improving LV function are more significant in patients with reduced LVEF at baseline.

MedicalResearch.com: What should clinicians and patients take away from your report?

Professor He: PVC-associated with LV dysfunction represents a potentially reversible syndrome that deserved catheter ablation although the long-term successful rate needs further improved.

MedicalResearch.com: What recommendations do you have for future research as a result of this study?

Professor He: Further studies are needed to target which group of patients would benefit the most in cardiac function improvement from frequent PVC ablation.

Citation:

Beneficial effects of catheter ablation of frequent premature ventricular complexes on left ventricular function

Minhua Zang, Tuo Zhang, Jialiang Mao, Shengheng Zhou, Ben He

Heart heartjnl-2013-305175Published Online First: 26 March 2014 doi:10.1136/heartjnl-2013-305175