omega three fatty acids- salmon

Omega-3 Fatty Acids Linked to Improved Outcomes after Heart Attack

MedicalResearch.com Interview with:

Antoni Bayes-Genis, MD, PhD, FESC, FHFA Head, Heart Institute. Hospital Universitari Germans Trias i Pujol Full Professor, Autonomous University Barcelona

Dr. Bayes-Genis

Antoni Bayes-Genis, MD, PhD, FESC, FHFA
Head, Heart Institute. Hospital Universitari Germans Trias i Pujol
Full Professor, Autonomous University Barcelona

MedicalResearch.com: What is the background for this study? What are the main findings?

Response: Omega-3 fatty acids are incorporated into the phospholipids of cellular membranes, including cardiac contractile cells, and have a wide range of demonstrated physiological effects. Several potential mechanisms have been investigated, including antiarrhythmic, anti-inflammatory, and endothelial.

Omega-3 fatty acids lower heart rate and improve heart rate variability, both associated with lower sudden cardiac death risk, one of the complications that may occur after a myocardial infarction.

Increased omega-3 fatty acids also enhance arterial elasticity by increasing endothelium-derived vasodilators, which is associated with blood pressure–lowering effects.
They also have a cardioprotective effect on platelet-monocyte aggregation, and lower triglyceride levels.

MedicalResearch.com: What should readers take away from your report?

Response: In the setting of STEMI the cardiac contractile cells (or cardiomyocytes) die and release their content (including the content of their lipidic membranes) to the circulation. Measurement of omega-3 in serum, as performed in our study, indicates enrichment of theses fatty acids in the lipid bilayer of the membranes of dying cardiomyocytes, and this is a proxy of the dietary intake of omega-3 fatty acids in the last 3-4 weeks.

Whether patients with a STEMI and high omega-3 do have other healthier lifestyle habits is beyond the scope of our study, but it certainly indicates healthy eating -in terms of a diet rich in cold-water oily fish (such as salmon, anchovies, herring, mackerel, tuna, sardines), seeds, and nuts- the weeks preceding the infarct, and this has impact on prognosis.

These data provide novel scientific evidence to strongly support the recommendation that omega-3 fatty acids be an integral component of a heart-healthy dietary pattern.

Clinicians should recommend eating food rich in omega-3 fatty acids in patients with STEMI to reduce the risk of adverse events during follow-up.

MedicalResearch.com: Is there anything else you would like to add?

Response: In the COVID-19 pandemic, more than ever, we need to do our best to stay healthy. A good way to stay healthy is to enrich our cell membranes with omega-3 fatty acids to keep ourselves home and to avoid having to see a doctor or visit an emergency room or a hospital 

Disclosures:

AstraZeneca, Vifor, Novartis, Boehringer Ingelheim, Abbott, Roche Diagnostics, and Critical Diagnostics.

No relationship relative to the contents of the manuscript to disclose.

Citation:

Circulating Omega-3 Fatty Acids and Incident Adverse Events in Patients With Acute Myocardial Infarction
Iolanda Lázaro, Ferran Rueda, Germán Cediel, Emilio Ortega, Cosme García-García, Aleix Sala-Vila, Antoni Bayés-Genís


2020 Nov, 76 (18) 2089-2097.

JOIN OUR EMAIL LIST

We respect your privacy and will never share your details.

Last Modified: Oct 27, 2020 @ 7:28 pm

The information on MedicalResearch.com is provided for educational purposes only, and is in no way intended to diagnose, cure, or treat any medical or other condition. Always seek the advice of your physician or other qualified health and ask your doctor any questions you may have regarding a medical condition. In addition to all other limitations and disclaimers in this agreement, service provider and its third party providers disclaim any liability or loss in connection with the content provided on this website.