TAVR vs Surgical Aortic Valve Replacement Among Low-Risk Patients With Aortic Stenosis

MedicalResearch.com Interview with:

Fausto Biancari, Professor of Surgery, University of Turku, Finland Professor of Cardiothoracic Surgery, University of Oulu, Finland Heart Center, T-Hospital, Hämeentie Turku, Finland

Prof. Biancari

Fausto Biancari, MD, PhD
University of Turku and University
Oulu, Finland

MedicalResearch.com: What is the background for this study?

Response: Current data is scarce regarding the short- and midterm benefit of transcatheter aortic valve replacement (TAVR) compared to surgical aortic valve replacement (SAVR) in low-risk patients with severe aortic valve stenosis.

MedicalResearch.com: What are the main findings?

Response: In this observational study on 2841 low-risk patients with aortic valve stenosis from the Finnish nationwide FinnValve registry, propensity score matching analysis showed similar 30-day and three-year survival after TAVR and SAVR.

MedicalResearch.com: What should readers take away from your report?

Response: Patients with severe aortic valve stenosis and low operative risk may be offered TAVR instead of SAVR. However, clinicians and patients should be aware that, contrary to surgical aortic valve prostheses, there is no data on the long-term durability of current transcatheter aortic valve prostheses.

MedicalResearch.com: What recommendations do you have for future research as a result of this study?

Response: Further studies are needed to assess the long-term durability of transcatheter aortic valve prostheses before extending the use of TAVR to low-risk patients with long expectancy of life.

Disclosure of potential conflicts of interest: Dr. Mikko Savontaus is proctor for Medtronic, the relationship is significant; Dr. Mika Laine is proctor for Boston Scientific, the relationship is significant. The other coauthors do not have any conflict of interest related to this study.


Virtanen MPO, Eskola M, Jalava MP, et al. Comparison of Outcomes After Transcatheter Aortic Valve Replacement vs Surgical Aortic Valve Replacement Among Patients With Aortic Stenosis at Low Operative Risk. JAMA Netw Open. Published online June 14, 20192(6):e195742. doi:10.1001/jamanetworkopen.2019.5742


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