08 Oct Lower Transfusion Threshold Safe For Most Sepsis Patients
Medical Research: What are the main findings of the study?
Dr. Perner: In the large international randomised trial, we showed similar outcomes in patients with septic shock with anemia transfused at a lower vs. a higher hemoglobin threshold. The lower threshold group received 50 % fewer transfusions and one-third of these patients were never transfused in ICU.
Medical Research: What was most surprising about the results?
Dr. Perner: The results were remarkably clear.
Medical Research: What should clinicians and patients take away from your report?
Dr. Perner: Clinicians treating patients with septic shock can safely wait and transfuse at a hemoglobin level at 7 g/dl
Medical Research: What recommendations do you have for future research as a result of this study?
Dr. Perner: For the vast majority of patients 7 g/dl should be the transfusion threshold, but we need more data in those with acute coronary syndrome or severe bleeding