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16 Aug Mitral Valve Regurgitation from Flail Leaflets: Early Surgical Intervention May be Warranted

Posted at 18:49h in Author Interviews, General Medicine, Heart Disease, Mayo Clinic, Surgical Research

MedicalResearch.com Interview with: Rakesh M. Suri MD, D.Phil. Mayo Clinic College of Medicine, Rochester, Minnesota MedicalResearch.com: What might clinicians “take home” from this study? Answers: a. The contemporary outcomes of surgical correction of mitral regurgitation are excellent based upon results observed in this large multinational, multi-institutional study, Mitral valve surgery...

16 Aug HIV plus Hepatitis C : Marjuana Did Not Worsen Liver Disease

Posted at 16:31h in Author Interviews, Hepatitis - Liver Disease, HIV, McGill

MedicalResearch.com Interview with: Marina Klein, MD, MSc, FRCP(C) Associate Professor of Medicine McGill University Health Centre Division of Infectious Diseases and Chronic Viral Illness Service 3650 Saint Urbain Montreal, Quebec H2X 2P4 Disease in HIV–Hepatitis C Coinfection: A Longitudinal Cohort Analysis MedicalResearch.com: What...

01 Aug Vulvar Cancer: Racial and Age Disparities

Posted at 04:27h in Author Interviews, Cancer Research, OBGYNE

Hemodialysis.com Interview with:: Marcela G. del Carmen, M.D., M.P.H Division of Gynecologic Oncology, Vincent Obstetrics and Gynecology Massachusetts General Hospital, 55 Fruit Street, Yawkey 9 E Boston, Massachusetts MedicalResearch.com: What are the main findings of the study? Answer: The study sample included 7,973 women, including 7,363 (92.3%) whites and 610...

25 Jul TAp73, a molecular relative of p53 Tumor Suppressor Protein, gives tumor cells a growth advantage

Posted at 17:57h in Author Interviews, Cancer Research, Nature, University of Pennsylvania

MedicalResearch.com Interview with: Xiaolu Yang, Ph.D. Professor of Cancer Biology at the Perelman School of Medicine University of Pennsylvania and the Abramson Family Cancer Research Institute, MedicalResearch.com: What are the main findings of the study? Dr. Yang: TAp73 is a structural homologue of the preeminent tumor suppressor p53, but its role in...

24 Jul MS Progression: Cannabis Active Ingredient Ineffective

Posted at 12:58h in Author Interviews, Cannabis, Lancet, Multiple Sclerosis, Neurological Disorders

MedicalResearch.com Interview with: Professor John Zajicek Professor of Clinical Neuroscience, Centre for Clinical Trials & Health Research – Translational & Stratified Medicine (Peninsula Schools of Medicine and Dentistry) MedicalResearch.com: What are the main findings of the study? Prof. Zajicek: Our study investigated whether dronabinol (one of the major active ingredients...

19 Jul Pre-Diabetes: Early Weight Loss Reduces Longer-Term Diabetes Risk

Posted at 01:23h in Author Interviews, Diabetes, Johns Hopkins, Weight Research

MedicalResearch.com Interview with: Nisa M. Maruthur, MD, MHS Assistant Professor of Medicine & Epidemiology The Johns Hopkins University Early Response to Preventive Strategies in the Diabetes Prevention Program MedicalResearch.com: What are the main findings of the study? Dr. Maruther: For patients engaged in a lifestyle intervention to prevent diabetes, weight...

15 Jul Blindness: Israel Dramatically Reduces New Cases

Posted at 21:30h in Author Interviews, Ophthalmology

MedicalResearch.com Interview with: Michael Belkin, MA, MD Professor of Ophthalmology Director, Ophthalmic Technologies Laboratory Goldschleger Eye Research Institute Tel Aviv University Sheba Medical Center Tel Hashomer 52621 Israel MedicalResearch.com: What are the main findings of the study? Dr. Belkin: Modern ophthalmic treatment, when freely available is able to reduce the...

15 Jul Type 1 Diabetes and Respiratory Infections in Childhood

Posted at 20:34h in Author Interviews, Diabetes, Infections, JAMA, Respiratory

MedicalResearch.com Interview with: Andreas Beyerlein, PhD Institute of Diabetes Research, Helmholtz Zentrum München and Forschergruppe Diabetes der Technischen Universität München, Munich, Germany MedicalResearch.com What are the main findings of the study? Dr. Beyerlein: We identified respiratory infections in early childhood, especially in the first year of life, as a risk...

09 Jul Diabetes in the Elderly: Indivualized Treatment with Vildagliptin (Glavus)

Posted at 15:35h in Author Interviews, Diabetes, Frailty, Lancet

MedicalResearch.com Interview with: Dr David Strain, MRCP MD Clinical senior lecturer and honorary consultant University of Exeter Medical School Institute of Biomedical and Clinical Science Department of Diabetes and Vascular Research Royal Devon & Exeter Hospital Exeter EX2 5AX MedicalResearch.com: What is the Background of the study? In early 2010...

04 Jul Type 2 Diabetes: Validating a Renal Risk Score

Posted at 11:40h in Diabetes, Kidney Disease

MedicalResearch.com Interview with: C Raina Elley Associate Professor and General Practitioner, Acting Head, Dept General Practice & Primary Health Care, Faculty Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand MedicalResearch.com: What are the main findings of the study? Answer: Type 2 Diabetes is the leading...

04 Jul Early Rheumatoid Arthritis: Biological vs Conventional Treatment and Work Loss

Posted at 00:16h in JAMA, Rheumatology

MedicalResearch.com Interview with: Jonas Eriksson, PhD-student Clinical Epidemiology Unit Karolinska Institutet, T2 171 76 STOCKHOLM Sweden Biological vs Conventional Combination Treatment and Work Loss in Early Rheumatoid Arthritis A Randomized Trial MedicalResearch.com: What are the main findings of the study? Answer: The main finding from this study is that in...

20 Jun Multiple Islet Autoantibodies in Childhood Indicates Diabetic Destiny

Posted at 17:20h in Diabetes, JAMA, Pediatrics

MedicalResearch.com Interview with: Dr. Ezio Bonifacio, Ph.D. Professor, Preclinical Stem Cells/Diabetes Center for Regenerative Therapies Dresden Technische Universität Dresden MedicalResearch.com: What are the main findings of the study? Dr. Bonifacio: Children who develop multiple islet autoantibodies are destined to develop diabetes. Only a minority will be diabetes-free 15 years after...

23 May Donated Kidneys May Serve as Scaffolding to Grow New Kidneys for Kidney Failure Patients

Posted at 18:56h in Wake Forest

MedicalResearch.com eInterview with Dr. Giuseppe Orlando, M.D., Ph.D. Instructor, General Surgery Specialty Areas: Transplant Urology, Kidney Transplantation, Pancreas Transplantation, Transplant Immunology, Transplant Immunosuppression, Transplant Surgery Wake Forest Baptist Medical Center Medical Center Boulevard, Winston-Salem, NC 27157. MedicalResearch.com: What are the main findings of the study? Dr. Orlando: Our study shows...

23 May Oxandrolone and Healing of Chronic Pressure Ulcers in Spinal Cord Injury

Posted at 18:43h in Author Interviews

MedicalResearch.com eInterview with Dr. William A. Bauman, MD Veterans Affairs Rehabilitation Research and Development National Center of Excellence for the Medical Consequences of Spinal Cord Injury Suite 7A-13, James J. Peters Veterans Affairs Medical Center 130 West Kingsbridge Road, Bronx, NY 10468; MedicalResearch.com: What are the main findings of the...

02 Apr Pathway-based personalized analysis of cancer

Posted at 14:50h in Author Interviews, Cancer Research, PNAS

MedicalResearch.com Author Interview: Prof. Eytan Domany Department of Physics of Complex Systems and Department of Biological Regulation, Weizmann Institute of Science, Rehovot, 76100, Israel MedicalResearch.com: What are the main findings of the study? Prof. Domany: The findings are two-fold: methodological and clinical. A novel method was introduced for personalized analysis...

30 Mar The subjective–objective mismatch in sleep perception among those with insomnia and sleep apnea

Posted at 21:40h in Author Interviews, Sleep Disorders

MedicalResearch.com Interview with Matt T. Bianchi MD PhD MMSc Assistant Professor Department of Neurology Director, Sleep Division Massachusetts General Hospital MedicalResearch.com: What are the main findings of the study? Dr. Bianchi: We showed that patients reporting symptoms of insomnia tend to under-estimate the amount of time they slept during overnight...

20 Mar Short Telomere Length, Cancer Survival, and Cancer Risk in 47102 Individuals

Posted at 12:05h in Author Interviews, Biomarkers, Cancer Research

MedicalResearch.com Interview with Stig E. Bojesen Staff specialist, MD, PhD, DMSci Dept. of Clinical Biochemistry, Copenhagen University Hospital Herlev Hospital DK-2730 Herlev Denmark MedicalResearch.com: What are the main findings of the study? Dr. Bojesen: The most interesting findings were the increased risk of early death after cancer by decreasing telomere...

11 Jul Identifying risky behaviors: The key to HIV prevention

Posted at 23:55h in HIV

HIV prevention must be better targeted, according to David Holtgrave from Johns Hopkins Bloomberg School of Public Health in the US, and colleagues. Health care professionals need a more detailed analysis and understanding of the interplay between HIV risk behavior, access to treatment and treatment success among those living with...

15 Mar Study Suggests Link Between H. pylori Bacteria and Blood Sugar Control in Adult Type II Diabetes

Posted at 02:24h in Diabetes, Infections, NYU/NYMC

Newswise — NEW YORK, March 14, 2012 – A new study by researchers at NYU Langone Medical Center reveals that the presence of Helicobacter pylori (H. pylori) bacteria is associated with elevated levels of glycosylated hemoglobin (HbA1c), an important biomarker for blood glucose levels and diabetes. The association was even stronger in...

09 Mar Researchers reveal ways to make personalized cancer therapies more cost effective

Posted at 22:21h in Cancer Research, Cost of Health Care

AURORA, Colo. — As scientists continue making breakthroughs in personalized cancer treatment, delivering those therapies in the most cost effective manner has become increasingly important. Now researchers at the University of Colorado School of Medicine have identified new ways of doing just that, allowing more patients to benefit from this...

09 Mar Study: Cancer of the Appendix is Different than Colon Cancer

Posted at 20:50h in Cancer Research, Colon Cancer, Duke, Nature, Wake Forest

WINSTON-SALEM, N.C. – March 7, 2012 – Researchers at Wake Forest Baptist Medical Center have demonstrated that cancer of the appendix is different than colon cancer, a distinction that could lead to more effective treatments for both diseases. The study by Edward A. Levine, M.D., professor of surgery and chief...

08 Dec Low Risk Prostate Cancer: Panel endorses active monitoring

Posted at 19:59h in Prostate Cancer

An independent panel convened this week by the National Institutes of Health has concluded that many men with localized, low-risk prostate cancer should be closely monitored, permitting treatment to be delayed until warranted by disease progression. However, monitoring strategies—such as active surveillance—have not been uniformly studied and available data do...

08 Dec Obese patients with HER2-positive breast cancer may have worse outcomes

Posted at 19:52h in Breast Cancer, Mayo Clinic

SAN ANTONIO — Obese patients with early-stage HER2-positive breast cancer may have worse outcomes than patients who are normal weight or overweight, Mayo Clinic researchers found in a study presented today at the 2011 CTRC-AACR San Antonio Breast Cancer Symposium. HER2-positive breast cancer gets its name from a protein called...

11 Oct Ovarian cancer patients survive longer with BRCA2 mutated in tumors

Posted at 23:42h in Cancer Research, MD Anderson, Ovarian Cancer

HOUSTON – Women with high-grade ovarian cancer live longer and respond better to platinum-based chemotherapy when their tumors have BRCA2 genetic mutations, researchers at The University of Texas MD Anderson Cancer Center and the Institute for Systems Biology report in the Oct. 12 issue of the Journal of the American...

06 Oct Survival increased in early stage breast cancer after treatment with herceptin and chemo

Posted at 02:12h in Breast Cancer

Treating women with early stage breast cancer with a combination of chemotherapy and the molecularly targeted drug Herceptin significantly increases survival in patients with a specific genetic mutation that results in very aggressive disease, a researcher with UCLA’s Jonsson Comprehensive Cancer Center reported Wednesday. The study also found that a...

05 Oct Blood Tests May Hold Clues to Pace of Alzheimer’s Disease Progression

Posted at 14:00h in Alzheimer's - Dementia, Baylor College of Medicine Houston, Mayo Clinic, Mental Health Research

Release Date: 10/03/2011 Johns Hopkins-led research suggests levels of certain fats in blood might predict rate of cognitive decline. A team of scientists, led by Johns Hopkins researchers, say they may have found a way to predict how quickly patients with Alzheimer’s disease (AD) will lose cognitive function by looking...

09 Sep Genomic analysis of superbug provides clues to antibiotic resistance

Posted at 22:46h in Antibiotic Resistance, Baylor College of Medicine Houston

HOUSTON – (Sept. 7, 2011) – An analysis of the genome of a superbug has yielded crucial, novel information that could aid efforts to counteract the bacterium’s resistance to an antibiotic of last resort. The results of the research led by scientists from The University of Texas Health Science Center...

08 Sep Aerobic exercise may reduce the risk of dementia

Posted at 10:56h in Alzheimer's - Dementia, Exercise - Fitness, Mayo Clinic

ROCHESTER, Minn. – Any exercise that gets the heart pumping may reduce the risk of dementia and slow the condition’s progression once it starts, reported a Mayo Clinic study published this month in Mayo Clinic Proceedings. Researchers examined the role of aerobic exercise in preserving cognitive abilities and concluded that...

16 Aug Pegloticase aids gout patients not helped by standard treatments

Posted at 23:09h in Gout, JAMA

Injections of pegloticase, a modified porcine enzyme, can produce significant and sustained clinical improvements in 2 out of 5 patients with chronic gout that is resistant to conventional therapies, researchers report in the August 17, 2011, issue of JAMA. In two controlled clinical trials, pegloticase rapidly lowered high levels of...

07 Aug Sporadic Mutations cause more than half the cases of Schizophrenia

Posted at 20:21h in Mental Health Research, Nature, Schizophrenia

Columbia University Medical Center researchers have shown that new, or “de novo,” protein-altering mutations—genetic errors that are present in patients but not in their parents—play a role in more than 50 percent of “sporadic” —i.e., not hereditary—cases of schizophrenia. The findings will be published online on August 7, 2011, in...