Bacterial Alterations Precede Necrotising Enterocolitis In Low Birthweight Infants

MedicalResearch.com Interview with:
Phillip I. Tarr, MD
Melvin E. Carnahan MD Professor of Pediatrics
Director, Pediatric Division of Gastroenterolgy and Nutrition
Washington University in St Louis School of Medicine
St Louis, MO 63110, USA

MedicalResearch.com: What is the background for this study? What are the main findings?

Dr. Tarr: There is a longstanding belief that gut bacteria are relevant to the developing necrotising enterocolitis (NEC). We have established dysbiosis in the gut before NEC occurs, suggesting this ecological perturbation might be causal.

MedicalResearch.com: What should clinicians and patients take away from your report?

Dr. Tarr: Nothing just yet. But, it does offer hope that by modulating these bacterial populations we can prevent this terrible disorder.

MedicalResearch.com: What recommendations do you have for future research as a result of this study?

Dr. Tarr: Correct this dysbiosis, and see if necrotising enterocolitis can be prevented.

MedicalResearch.com: Thank you for your contribution to the MedicalResearch.com community.

Citation:

Gut bacteria dysbiosis and necrotising enterocolitis in very low birthweight infants: a prospective case-control study
Warner, Barbara B et al.
The Lancet , Volume 0 , Issue 0
DOI: http://dx.doi.org/10.1016/S0140-6736(16)00081-7
Published Online:08 March 2016

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Phillip I. Tarr, MD (2016). Bacterial Alterations Precede Necrotising Enterocolitis In Low Birthweight Infants

Last Updated on March 9, 2016 by Marie Benz MD FAAD