Microbiome in Early Adolescent Acne Changes Over Time

MedicalResearch.com Interview with:

Dr. Jusleen Ahluwalia MDSecond-year Dermatology residentUniversity of California, San Diego

Dr. Ahluwalia

Dr. Jusleen Ahluwalia MD
Second-year Dermatology resident
University of California, San Diego

MedicalResearch.com: What is the background for this study? What are the main findings? 

Response: Preadolescence is an interesting stage during which changes in microbial diversity can coincide with the development of acne. This study is the largest assessment of preadolescent acne microbiome in the literature to date.

In this study, we found that early acne in preadolescent females is characterized by an abundance of Streptococcus mitis, while later stages are characterized by a predominance of Cutibacterium acnes (formerly known as Propionibacterium acnes).  

MedicalResearch.com: What should readers take away from your report?

Response: This study is important as it reveals that microbes other than C. acnes can play a role in preadolescent acne. Although we noted around a 40% clinical reduction in the number of acne lesions, we did not notice a significant change in the preadolescent microbiome after treatment with benzoyl peroxide.

MedicalResearch.com: What recommendations do you have for future research as a result of this work? 

Response: Future research should assess the antibacterial role of benzoyl peroxide in preadolescent acne.

Dr. Jusleen Ahluwalia is a second-year dermatology resident at the University of California, San Diego. She is from Princeton, New Jersey. She graduated from the accelerated BA/MD program with UMDNJ-Robert Wood Johnson Medical School and then pursued her intern year in Internal Medicine at the Icahn School of Medicine at Mount Sinai. Before starting residency, she participated in a research fellowship under the mentorship of Dr. Lawrence Eichenfield.

Dr. Ahluwalia was honored as a member of the Alpha Omega Alpha Medical Honor Society during medical school, has presented at a variety of conferences including the AAD, ASLMS, Fall Clinical, Coastal Derm Symposium, and Harvard Laser Course, and is a recipient of the ASLMS Student Research, AAD Sulzberger, and the Everett C. Fox, MD Memorial Awards. 

Citation:

Pediatr Dermatol. 2019 Mar;36(2):200-206. doi: 10.1111/pde.13741. Epub 2019 Jan 18.

The microbiome in preadolescent acne: Assessment and prospective analysis of the influence of benzoyl peroxide.

Ahluwalia J1,2, Borok J1,2, Haddock ES1,2, Ahluwalia RS1,2, Schwartz EW3, Hosseini D3, Amini S3, Eichenfield LF1,2.

 

Apr 30, 2019 @ 12:11 pm

 

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