21 Sep Too Much or Too Little Sleep Linked to Cognitive Decline
MedicalResearch.com Interview with:
Wuxiang Xie, PhD
Peking University Clinical Research Institute
Peking University First Hospital
MedicalResearch.com: What is the background for this study?
Response: Dementia is one of the most common and serious disorders in later life. A strong relationship between sleep and cognitive function had been previously reported, while the relationship between sleep duration and the trajectory of cognitive decline remains unclear.
MedicalResearch.com: What are the main findings?
Response: Global cognitive function in individuals with extreme sleep durations (≤ 4 or ≥ 10 hours per night) declined significantly faster than that in the reference group (7 hours per night) after adjusting for covariates.
MedicalResearch.com: What should readers take away from your report?
Response: There is an inverted U-shaped association between sleep duration and global cognitive decline.
MedicalResearch.com: What recommendations do you have for future research as a result of this work?
Response: Future mechanism studies as well as intervention studies examining the association between sleep duration and cognitive decline are required.
MedicalResearch.com: Is there anything else you would like to add?
Response: This study is an observational study and cannot demonstrate a causal relationship.
Ma Y, Liang L, Zheng F, Shi L, Zhong B, Xie W. Association Between Sleep Duration and Cognitive Decline. JAMA Netw Open. 2020;3(9):e2013573. doi:10.1001/jamanetworkopen.2020.13573
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