18 Feb Fast Stroke Treatment Key To Better Outcomes
MedicalResearch.com Interview with:
Michael D Hill, MD MSc FRCPC
Calgary Stroke Program
Professor, Dept Clinical Neurosciences
Hotchkiss Brain Institute
Cumming School of Medicine, University of Calgary
Medical Research: What is the background for this study? What are the main findings?
Dr. Hill: The HERMES collaboration is a pooled analysis of 5 randomized controlled trials of endovascular stroke therapy. The purpose is of this analysis is to assess the relationship between time from stroke onset and effect size.
The main finding is that there is a declining effect size as time elapses from stroke onset. Shorter onset to reperfusion times are associated with better outcomes. However, the slope of the decline is shallow compared to past estimates. We believe this is because imaging selection identifies a group a patients in whom there is slow growth of the core infarct.
Medical Research: What should clinicians and patients take away from your report?
Dr. Hill: Fast treatment remains critical to achieve good outcomes.
Medical Research: What recommendations do you have for future research as a result of this study?
Dr. Hill: Rapid workflow must be achieved at all centres and further work is needed to establish the best methods to achieve this kind of fast workflow metrics. Target metrics should be established and these should be aggressively short.
Medical Research: Is there anything else you would like to add?
Dr. Hill: The results are relevant to multiple jurisdictions, countries and health care systems.
The first paper from the HERMES analysis will be published on-line in the Lancet
(18 Feb 2016)
Safety and Efficacy of Solitaire Stent Thrombectomy Individual Patient Data Meta-Analysis of Randomized Trials Bruce C.V. Campbell, MBBS, PhD*; Michael D. Hill, MD, MSc*; Marta Rubiera, MD*; Bijoy K. Menon, MD, MSc*; Andrew Demchuk, MD; Geoffrey A. Donnan, MD; Daniel Roy, MD; John Thornton, MD; Laura Dorado, MD, PhD; Alain Bonafe, MD; Elad I. Levy, MD; Hans-Christoph Diener, MD, PhD; María Hernández-Pérez, MD; Vitor Mendes Pereira, MD; Jordi Blasco, MD; Helena Quesada, MD; Jeremy Rempel, MD; Reza Jahan, MD; Stephen M. Davis, MD; Bruce C. Stouch, PhD; Peter J. Mitchel
February 18, 2016
Dr. Michael D. Hill (2016). Fast Stroke Treatment Key To Better Outcomes