Oral Anticoagulants Still Underused in AFib Patients

MedicalResearch.com Interview with:
Anna Gundlund, MD, PhD

Herlev-Gentofte Hospital, Department of Cardiology
Denmark 

MedicalResearch.com: What is the background for this study? What are the main findings?

Response: Atrial fibrillation increases a person’s risk of ischemic strokes up to 5-fold. Oral anticoagulation therapy lowers this risk effectively (>60%) and is therefore recommended for patients with atrial fibrillation and at least 1-2 other risk factors for stroke.

Our study show, that oral anticoagulation therapy is still underused in patients with atrial fibrillation – even after a stroke event. In stroke survivors with atrial fibrillation, oral anticoagulation therapy were associated with better outcomes than no oral anticoagulation therapy. 

MedicalResearch.com: What should readers take away from your report?

Response: Oral anticoagulation therapy is effective (and safe) as secondary stroke prophylaxis in patients with atrial fibrillation.

MedicalResearch.com: What recommendations do you have for future research as a result of this work? 

Response: Treatment rates with oral anticoagulation therapy have increased over time and we should keep on being aware that this tendency continues.

No disclosures

Citation:

Gundlund A, Xian Y, Peterson ED, et al. Prestroke and Poststroke Antithrombotic Therapy in Patients With Atrial FibrillationResults From a Nationwide CohortJAMA Network Open. 2018;1(1):e180171. doi:10.1001/jamanetworkopen.2018.0171

 

 

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