MedicalResearch.com Interview with:
Dr. Sarah Dermody, PhD
School of Psychological Science
Oregon State University
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Drinking alcohol is a risk factor for sustained smoking. In a sample of daily cigarette smokers receiving treatment for alcohol use disorder, we examined if reductions in drinking corresponded with reductions in nicotine metabolism as indexed by the nicotine metabolite ratio. The nicotine metabolite ratio is important because it is associated with smoking level and lapses. We found that for men, alcohol use and the nicotine metabolite ratio reduced significantly; however, for women, neither drinking nor nicotine metabolite ratio changed.
MedicalResearch.com: What should readers take away from your report?
Response: Heavy drinking may increase the nicotine metabolite ratio, which we found is reversed with reduced drinking.
MedicalResearch.com: What recommendations do you have for future research as a result of this work?
Response: It is important to establish if reductions in the nicotine metabolite ratio could make it easier for individuals to reduce their smoking or ultimately quit smoking cigarettes.
Sarah S Dermody, Christian S Hendershot, Allyson K Andrade, Maria Novalen, Rachel F Tyndale. Changes in Nicotine Metabolite Ratio among Daily Smokers receiving Treatment for Alcohol Use Disorder. Nicotine & Tobacco Research, 2018; DOI: 10.1093/ntr/nty265
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