MedicalResearch.com Interview with: [caption id="attachment_42676" align="alignleft" width="125"] Dr. Rothberg[/caption] Dr. Amy Rothberg MD PhD Associate Professor, Endocrinology and Medicine Michigan Medicine Metabolism, Endocrinology and Diabetes Clinic University of Michigan  MedicalResearch.com: What is the background for this study? Would you briefly outline the essentials of the Optifast plan? Response: OPTIWIN is a year-long, multi-center, open-label, randomized, head-to-head study. It was designed to evaluate the effectiveness of the medically-monitored, meal replacement OPTIFAST Program on weight loss and maintenance, in comparison with a standard-of-care, food-based diet among adults with a BMI higher than 30 kg/m2. Nestlé Health Science’s OPTIFAST Program combines proven essential features of weight loss success ‒ medical monitoring, nutrition education, exercise guidance, in-person support, full meal replacement and behavior modification. With OPTIFAST meal replacement products, the program gives patients the prescribed amount of calories and micronutrients each day. It is a non-surgical option designed for people with a Body Mass Index (BMI) greater than 30, and is available in more than 400 weight loss clinics nationwide. The Program is comprised of three core phases ‒ active weight loss (during which total diet replacement is used), transition to self-prepared ‘everyday’ meals and maintenance. Clinical supervision is a key component of the program as it helps assess progress towards better health and emotional well-being.