Malignant hematology trials are becoming a competitive landscape for sponsors, who have to balance a relatively small cohort of patients,...
Many adults seek clear help with weight loss since plans often use powerful drugs and regular checks. Clinics with these...
Dr. Zorrilla[/caption]
MedicalResearch.com Interview with:
Julian Zorrilla, DO
Pediatric Hematologist/Oncologist
Nemours Children’s Health
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Non-factor therapies are a novel treatment approach for people with hemophilia A and B with and without inhibitors.
Fitusiran is a first-of-its-kind “rebalancing” agent that provides effective hemostatic control from bleeds in people with hemophilia. This study describes the experience of people with hemophilia who are on fitusiran in regard to minor surgeries. This data shows minor surgeries can be effectively and safely performed for those patients who are on fitusiran for their prophylaxis. A subset of individuals on fitusiran did not require any other medications to help prevent surgical bleeding.
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Alexa T. Diianni[/caption]
MedicalResearch.com Interview with:
Alexa T. Diianni, MBS
Department of Medical Education
Geisinger College of Health Sciences
Scranton, PA 19409
MedicalResearch.com: What is the background for this study?
Response: During a previous study, my research team and I examined the financial conflicts of interest (COIs) between industry and academia- namely those that exist between authors of The American Psychiatric Association’s Diagnostic and Statistical Manual of Mental Disorders (DSM), and industry (1). The DSM is a diagnostic tool widely used for the diagnosis of psychiatric disorders, and is thus of interest in assessing COIs (1,2). We previously found that authors of the DSM-5-TR had received over $14.2m in undisclosed payments from industry (1). Our current study examines the gender and geographic disparities of the DSM-5-TR authors, in relation to these payments.
While previous investigations have evaluated financial COIs in recent editions of the DSM (3,4), the demographic information of its authors has not yet been examined. Equitable representation of DSM authors is paramount as this manual serves a diverse population across the United States and beyond. It is important that the authorship of this manual be reflective of the population in which it serves, as there have been reported differences in both the type and prevalence of psychiatric care sought out by gender, as well as varying clinical treatment by geographic location (5-8). 
Dr. Gogate[/caption]
MedicalResearch.com Interview with:
Dr. Shaila Gogate, MD
Colorado Allergy & Asthma Centers
Allergist
REMIX-1/-2 Investigator
MedicalResearch.com: What is the background for this study? What are the main findings?
A: The Phase III REMIX-1/-2 studies were randomized, double-blind, placebo-controlled studies assessing the efficacy and safety of oral remibrutinib 25 mg twice daily or placebo over a 24-week double-blind period, followed by a 28-week open-label remibrutinib treatment period.
The purpose of this pooled analysis was to examine the early and long-term efficacy data of remibrutinib vs. placebo over time, looking at the mean percentage change from baseline (CFB) in weekly scores of disease activity (UAS7), itch severity (ISS7) and hives severity (HSS7) over 52 weeks. This analysis demonstrated that remibrutinib showed reductions in urticaria symptoms vs. placebo as early as week 1:
Dr. Mosnaim[/caption]
Dr. Giselle Mosnaim MD MS FACAAI
Allergist
Division of Allergy and Immunology
Department of Medicine
Northshore University Health System
REMIX-1/-2 Investigator
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Chronic spontaneous urticaria is a debilitating condition significantly affecting patient quality of life and is characterized by the presence of itch, hives, and/or angioedema (swelling) lasting for greater than 6 weeks, without identifiable trigger. Second-generation H1-antihistamines at standard doses are recommended as first-line treatment for patients with chronic spontaneous urticaria, and can be up-dosed to 4 times the standard dose. However, over 50% of patients continue to have symptoms despite this therapy. Both Remibrutinib and Dupilumab are FDA-approved for the treatment of chronic spontaneous urticaria in adult patients (Remibrutinib ≥ 18 years old and Dupilumab ≥ 12 years old) who remain symptomatic despite second-generation H1-antihistamine treatment.
The RECLAIM study is an ongoing head-to-head randomized controlled trial comparing the efficacy of Remibrutinib, an oral Bruton’s tyrosine kinase inhibitor, and Dupilumab, an injectable anti-interleukin-4 and anti-interleukin-13 inhibitor, at early timepoints (4 weeks and earlier) when administered as an add-on therapy in adults with moderate to severe chronic spontaneous urticaria inadequately controlled by second-generation H1-antihistamines.
Dr. Kruger[/caption]
MedicalResearch.com Interview with:
Daniel J. Kruger, PhD
Population Studies Center, Institute for Social Research
University of Michigan
MedicalResearch.com: What is the background for this survey?
Response: Multiple studies indicate that psychedelic use is at an all-time high. There are hundreds of clinical trials on the use of psychedelics and psychedelic-derived compounds for potential mental health benefits. Popular books like Michael Pollan’s “How to Change Your Mind” have raised public awareness of these substances and their potential benefits. Legislative changes in some areas have liberalized psychedelic access for therapy and personal use. Still, the vast majority of those who use psychedelics will use them outside of regulated, supervised settings. People are reporting both amazing therapeutic benefits as well as adverse experiences, and sometimes detrimental effects that last well beyond the trip. This study aimed to develop a risk-reduction resource to facilitate safe and successful psychedelic experiences outside of regulated settings. We employed a community-based approach to crowdsource practical recommendations for first-time psychedelic experiences from the psychedelic community.
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MAT combines FDA-approved medications with counseling, behavioral therapy, and support services to treat substance use disorders (especially opioid and alcohol use disorders). The goal is to reduce cravings, ease withdrawal, prevent relapse, and help people build stability in recovery.
In Rhode Island, MAT is offered at specialized clinics, community treatment centers, and designated opioid-treatment programs (OTPs), including those connected to statewide initiatives for opioid use support.
Freepix[/caption]
Intensive Outpatient Programs provide a higher level of structure and support while still allowing clients to live at home. An...
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Complex post-traumatic stress disorder, often shortened to CPTSD or cPTSD, has moved from a niche clinical idea to a term many people now use for their own lived experience. At the same time, it is still not listed as a standalone diagnosis in the Diagnostic and Statistical Manual of Mental Disorders (DSM). That leaves many people asking a very specific question: Will CPTSD be added to the Diagnostic and Statistical Manual of Mental Disorders in 2026?
The most accurate answer is that there is currently no official commitment to adding complex PTSD to the DSM in 2026. As of late 2025, CPTSD is recognized in the World Health Organization’s International Classification of Diseases, 11th edition (ICD-11), but not in the DSM-5 Text Revision (DSM-5 TR). Clinicians and researchers are actively debating whether a new CPTSD diagnosis should be included in a future DSM edition, yet no formal decision or fixed timeline has been announced.
The question itself opens the door to important issues and questions, which MedicalResearch.com will review and address in this article. How do major diagnostic manuals change over time? Why is CPTSD in the ICD but not in the DSM? And what does any of this mean if you or someone you love is living with the effects of long-term trauma?
Dr. Swartz[/caption]
MedicalResearch.com Interview with:
James A. Swartz, PhD
Professor, Jane Addams College of Social Work
University of Illinois Chicago
MedicalResearch.com: What is the background for this study?
Response: For the past 5 1/2 years, my project team has been charged with monitoring the public health effects of adult cannabis use legalization in Illinois. To fulfill that obligation, we have monitored state data and have tried to keep informed about ongoing research on cannabis legalization and public health. Cannabinoid hyperemesis syndrome (CHS) rose to the surface of this continual monitoring through a growing number of publications indicating the prevalence of this condition was on the rise and clinical case reports. As context, for any readers unfamiliar with the clinical syndrome, CHS is a paradoxical reaction to long-term, heavy cannabis use. Instead of relieving nausea, cannabis in some people appears to trigger cycles of severe nausea, vomiting, and abdominal pain. Patients often present repeatedly to emergency departments, undergo extensive workups, and only much later does someone connect the dots and consider CHS. Resource use is substantial. CHS visits often involve repeat ED presentations, imaging, laboratory testing, and sometimes hospital admission. Even though CHS is rarely life-threatening, it is not a trivial condition from either the patient’s or the system’s perspective.
Most of the existing literature has been case reports, small series, or single-center studies. Those reports clearly show that CHS can be debilitating and is frequently misdiagnosed, but they don’t tell us much about the bigger picture:
Our goal was to step back and use a large national emergency department database to describe CHS at scale in the United States from 2016 through 2022.
Eye doctors use comprehensive screenings to detect undiagnosed conditions in the early stages enabling them to establish proper treatment plans...
Braces create additional surfaces where food particles can become trapped, requiring careful brushing and specialized flossing tools. In contrast, clear...
Dr. Krause[/caption]
Kristen D. Krause, PhD, MPH (she/her/hers)
Assistant Professor, Department of Urban-Global Public Health
Deputy Director, Center for Health, Identity, Behavior and Prevention Studies (CHIBPS)
Rutgers School of Public Health
Deputy Editor, Annals of LGBTQ Public and Population Health
Deputy Editor, Behavioral Medicine
MedicalResearch.com: What is the background for this study?
Response: Young sexual minority men often face myriad challenges including stigma, heightened risk for mental health issues, and an increased likelihood of substance use. This study set out to shine a light on how ADHD symptoms might factor into these risks—a topic rarely examined directly in this population.
MedicalResearch.com: What are the main findings?
Response: We found that ADHD symptoms are not only common, but they are associated with increased odds of both early and frequent substance use, spanning everything from cigarettes to alcohol and more illicit substances. These results don’t just fill a gap, they invite attention to a complex interplay of identity, mental health, and behavior.
Photo by Karola G[/caption]
The relationship between oral health and brain health is closer than most people realize. In recent years, researchers have uncovered mounting evidence that poor oral hygiene can do more than damage your teeth and gums—it may also affect how your brain functions. This connection, known as the “mouth-brain link,” is gaining increasing attention in medical and dental communities.
The importance of robust pharmaceutical storage is only set to increase as personalized medicine, cell therapies, and complex biologics become...
Source Photo by Pixabay[/caption]
If you’ve recently undergone surgery, whether orthopedic, abdominal, or postpartum, post-surgery physiotherapy can mean the difference between lingering pain and a full, confident return to daily life or sport. At Form Recovery & Wellness, we’ve worked with hundreds of patients post-ACL reconstruction, shoulder repairs, spinal surgery, and C-sections—building patient-centric based rehab plans that accelerate healing and reduce complications.
This article outlines the four primary phases of physiotherapy post-surgery, how each stage contributes to optimal recovery, and what patients should expect.
For those recovering in Thailand, Form Recovery & Wellness provides internationally trained physiotherapists with extensive experience in post-operative rehabilitation. Their patient-centered approach ensures that treatment is tailored, data-driven, and aligned with global best practices.
Phase 1: Immediate Recovery (Days 1–14)
Goal: Reduce swelling, protect the surgical site, and initiate gentle movement.
In the first two weeks, physiotherapy interventions are focused on minimizing inflammation, activating surrounding muscles, and preventing stiffness or compensation patterns.
Photo by RDNE Stock project: https://www.pexels.com/photo/doctor-looking-at-the-time-6129111/[/caption]
Clinical rotations represent one of the most meaningful stages in a nurse practitioner program. These experiences allow students to move beyond classroom learning and begin participating directly in patient care, where clinical reasoning and communication skills take shape.
For many NP students, this is the first opportunity to observe how advanced practice providers work within real healthcare environments and to understand the daily responsibilities of the role they are preparing to enter.
With thoughtful preparation and consistent engagement, clinical rotations become a valuable part of an NP student’s educational journey.
Whereas Western physiology and psychology have used the somatotype system of ectomorph, mesomorph, and endomorph to describe broad patterns in human body composition, metabolism, and temperament for almost a century, Ayurveda, the classical health science of India, has utilized a remarkably similar framework for over 2,000 years: Vata, Pitta, and Kapha body types, or prakriti.
Although these two systems evolved independently, initial data indicate that they could be describing similar constitutional patterns. Recent studies from India and the West aimed to correlate the two classification models, and the results are interesting enough to warrant clinical interest.
The article reviews the scientific attempts at correlating Western somatotypes with Ayurvedic constitutions, their limitations, and explores what this convergence might mean for personalized lifestyle medicine.
Freepix image[/caption]
Receiving a diagnosis of multiple sclerosis (MS) can be a life-altering event, bringing with it many questions about the future. MS is a condition of the central nervous system that disrupts communication between the brain and the body. Its effects vary widely from person to person, but recent progress in medical science offers more hope and better outcomes than ever before. The focus of care has expanded from simply managing symptoms to actively slowing the condition's progression and improving overall quality of life.
Modern approaches to managing MS have transformed what it means to live with the condition. With a growing range of therapies, people with MS now have more opportunities to maintain their independence and continue participating in the activities they enjoy. These developments reflect a deeper recognition of how the disease works, leading to more targeted and convenient treatment plans.
Victoria Bethel[/caption]
MedicalResearch.com Interview with:
Victoria Bethel, MSN
Department of Public Administration and Policy
University of Georgia, Athens
MedicalResearch.com: What is the background for this study?
Response: From the same pool of commercially insured patients, we found that cannabis dispensary openings were associated with reduced opioid prescribing among patients with non-cancer pain.
For this study, we examined whether cannabis dispensary openings were also associated with reduced opioid prescribing among commercially insured patients who do have a cancer diagnosis.
Similar to patients without cancer, we estimated reductions in opioid prescribing after medical and recreational cannabis dispensaries open. These findings may suggest that patients who experience cancer pain are able to manage their pain with cannabis instead of requiring opioids, although we cannot directly observe substitution.
Source[/caption]
If you live in a growing community like Pickerington, you’ve probably noticed how much emphasis families place on children’s health, from balanced diets and sports to routine medical checkups. Yet one area that often goes unnoticed is dental development. Good oral health is about more than just bright smiles. It influences how children eat, speak, and even grow.
Many parents assume orthodontic treatment is something reserved for the teenage years, but experts often recommend earlier evaluations. By identifying potential bite or alignment issues early, orthodontists can guide proper jaw and tooth growth before problems become more complicated. In communities like Pickerington, where families value proactive care, early orthodontic attention is helping children achieve lasting oral health and confidence.
Understanding the Value of Early Orthodontic Care
When it comes to healthy smiles, timing makes all the difference. Early orthodontic intervention involves assessing how a child’s teeth and jaws are developing, often as young as age seven. At this stage, orthodontists can spot subtle issues such as crowding, bite misalignment, or early signs of jaw imbalance.
For families exploring orthodontics services in Pickerington, early consultations give children the advantage of preventive care. Orthodontists in the area focus on evaluating growth patterns, monitoring developing teeth, and using gentle techniques to guide them into better alignment. They can help ensure that permanent teeth emerge correctly and that the bite functions properly, reducing the risk of more complex treatments in the future.
By acting early, parents can help their children avoid the discomfort, expense, and extended treatment times that often come with delayed orthodontic correction. Early intervention isn’t just about creating straight teeth. It’s about promoting proper development and overall wellness.
In today's rapidly evolving digital landscape, the necessity for robust patient engagement strategies has never been more apparent. Marketers are constantly on the lookout for innovative ways to capture and retain patient attention, amidst a sea of competitive voices. Enter multi-channel marketing automation, a game-changing approach allowing businesses to consistently reach their audience through an orchestrated symphony of communication channels. This strategy ensures that every patient touchpoint is not only reached but optimized for maximum impact and conversion. Below, we delve into how embracing this technology can revolutionize the art of connecting with your audience.
Multi-channel marketing automation helps practices connect with patients across platforms like email, social media, and SMS, ensuring a consistent brand message while boosting engagement. By automating repetitive tasks, marketers can focus more on strategy and creativity, resulting in campaigns that are cohesive and efficiently delivered.
Understanding what is multi-channel marketing automation, especially through tools like Adestra, is key to thriving in today’s digital space. It not only simplifies marketing efforts but also allows for personalized, data-driven messaging that strengthens patient relationships, increases loyalty, and drives sales.