Cannabis / 26.11.2025

Editor’ note:  Cannabis and THCA/HEMP CBD products should have an active ingredient list on the container and have a Certificate of Analysis (COA)/Discuss your use of THC, Cannabis or CBD products with your health care provider.  Dosing of CBD is variable, especially since it is not FDA regulated. Cannabis/CBD may interfere with other medications and should not be used in individuals with certain health conditions, including liver issues. CBD skin care products can be absorbed through the skin and have similar effects. Do not use Cannabis products including edibles and CBD if you are pregnant, nursing or may become pregnant. Do not use cannabis products if driving or operating difficult or dangerous machinery. Children should not be exposed to cannabis or CBD products. Boom of Modern-Day Wellness Helpers.png Wellness today looks very different from what it was even five years ago. People now want relief that is quiet, simple, and easy to integrate into a busy lifestyle. This shift has led to the rise of subtle, modern-day wellness tools and products designed to support balance without demanding time or major daily changes. Innovations such as CBD patches wholesale, clean CBD liquid wholesale solutions, and fast-acting CBD shots in the UK demonstrate just how far the wellness landscape has evolved. For many consumers, the new goal isn’t dramatic transformation; it’s small, consistent improvements that feel effortless. The modern consumer is more informed, more selective, and more focused on practicality than ever before. Instead of relying on complicated wellness rituals or lengthy sessions of self-care, people now seek micro-relief solutions that deliver genuine benefits in minutes, not hours. This is where subtle aids like patches, liquids, shots, and micro-dose formats have changed the game.

Why Subtle Wellness Is So Popular Today

People don’t want to overhaul their routines they want products that slip into daily life without friction. Subtle wellness solutions work because they remove barriers: no prep time, no steep learning curve, no noticeable interruption. Whether someone is at work, travelling, or winding down at home, these aids offer an easy way to regain balance. Today’s wellness movement is built on three traits:
  1. Convenience
Consumers want tools that don’t demand major adjustments. Subtle wellness allows support anytime, anywhere.
  1. Discretion
Not everyone wants their wellness routines on display. Patches, liquids, and shots offer quiet ways to feel better without drawing attention.
  1. Speed
Stress, tension, and burnout don’t wait for scheduled rituals. People need fast-acting relief they can count on instantly. This is exactly why CBD-focused products have grown so quickly; they fit all three criteria.
Author Interviews, Cannabis, JAMA / 25.11.2025

Editor’ note:  Cannabis and THCA/HEMP CBD products should have an active ingredient list on the container and have a Certificate of Analysis (COA). Discuss your use of THC, Cannabis or CBD products with your health care provider.  Dosing of CBD is variable, especially since it is not FDA regulated. Cannabis/CBD may interfere with other medications and should not be used in individuals with certain health conditions, including liver issues. CBD skin care products can be absorbed through the skin and have similar effects. Do not use Cannabis products including edibles and CBD if you are pregnant, nursing or may become pregnant. Do not use cannabis products if driving or operating difficult or dangerous machinery. Children should not be exposed to cannabis or CBD products. [caption id="attachment_71501" align="alignleft" width="157"]Dr. Swartz Dr. Swartz[/caption] MedicalResearch.com Interview with: James A. Swartz, PhD Professor, Jane Addams College of Social Work University of Illinois Chicago MedicalResearch.com: What is the background for this study? Response: For the past 5 1/2 years, my project team has been charged with monitoring the public health effects of adult cannabis use legalization in Illinois. To fulfill that obligation, we have monitored state data and have tried to keep informed about ongoing research on cannabis legalization and public health. Cannabinoid hyperemesis syndrome (CHS) rose to the surface of this continual monitoring through a growing number of publications indicating the prevalence of this condition was on the rise and clinical case reports. As context, for any readers unfamiliar with the clinical syndrome, CHS is a paradoxical reaction to long-term, heavy cannabis use. Instead of relieving nausea, cannabis in some people appears to trigger cycles of severe nausea, vomiting, and abdominal pain. Patients often present repeatedly to emergency departments, undergo extensive workups, and only much later does someone connect the dots and consider CHS. Resource use is substantial. CHS visits often involve repeat ED presentations, imaging, laboratory testing, and sometimes hospital admission. Even though CHS is rarely life-threatening, it is not a trivial condition from either the patient’s or the system’s perspective.

Most of the existing literature has been case reports, small series, or single-center studies. Those reports clearly show that CHS can be debilitating and is frequently misdiagnosed, but they don’t tell us much about the bigger picture:

  • How often Cannabinoid hyperemesis syndrome is showing up in emergency departments nationally
  • How those rates have changed over time, especially as cannabis policies and patterns of use have shifted
  • What the typical patient profile looks like at a population level

Our goal was to step back and use a large national emergency department database to describe CHS at scale in the United States from 2016 through 2022.

Author Interviews, Cannabis, JAMA, Opiods / 13.11.2025

[caption id="attachment_71419" align="alignleft" width="150"]MedicalResearch.com Interview with:Victoria Bethel, MSN Department of Public Administration and Policy University of Georgia, Athens Victoria Bethel[/caption] MedicalResearch.com Interview with: Victoria Bethel, MSN Department of Public Administration and Policy University of Georgia, Athens   MedicalResearch.com: What is the background for this study? Response: From the same pool of commercially insured patients, we found that cannabis dispensary openings were associated with reduced opioid prescribing among patients with non-cancer pain. For this study, we examined whether cannabis dispensary openings were also associated with reduced opioid prescribing among commercially insured patients who do have a cancer diagnosis. Similar to patients without cancer, we estimated reductions in opioid prescribing after medical and recreational cannabis dispensaries open. These findings may suggest that patients who experience cancer pain are able to manage their pain with cannabis instead of requiring opioids, although we cannot directly observe substitution.
Cannabis / 01.10.2025

Editor’ note:  Cannabis and THCA/HEMP CBD products should have an active ingredient list on the container and have a Certificate of Analysis (COA). Discuss your use of THC, Cannabis or CBD products with your health care provider.  Dosing of CBD is variable, especially since it is not FDA regulated. Cannabis/CBD may interfere with other medications and should not be used in individuals with certain health conditions, including liver issues. CBD skin care products can be absorbed through the skin and have similar effects. Do not use Cannabis products including edibles and CBD if you are pregnant, nursing or may become pregnant. Do not use cannabis products if driving or operating difficult or dangerous machinery. Children should not be exposed to cannabis or CBD products. [caption id="attachment_70829" align="aligncenter" width="500"]shopping cannabis products Photo by Kindel Media[/caption] With so many options available online and through local delivery services, it’s important to shop smart. Not every provider follows the same safety and quality standards — which means consumers must know what to look for before placing an order. Licensed and transparent providers make this easy, while unverified sources often cut corners that can put buyers at risk. Here’s a simple checklist to keep in mind before making your next purchase.

✅ Verify Licensing and Compliance

The first step in safe shopping is making sure the business is licensed and compliant with state regulations. Licensed shops are required to meet strict testing, labeling, and storage standards, ensuring safer products for customers.
  • Confirm that the business is legally operating in your area.
  • Check for customer reviews that mention professionalism and trustworthiness.
  • Avoid sellers that don’t clearly disclose compliance details.
Licensed services like Kravings Delivery in Lynwood are trusted by local customers because they prioritize compliance and accountability with every order.
Author Interviews, Cannabis, Diabetes / 16.09.2025

[caption id="attachment_70686" align="alignleft" width="150"]Ibrahim Kamel, MD, MHABoston Medical Center – Brighton Clinical Instructor Boston Medical Center Boston University Dr. Kamel[/caption] MedicalResearch.com Interview with: Ibrahim Kamel, MD, MHA Boston Medical Center – Brighton Clinical Instructor Boston Medical Center Boston University   MedicalResearch.com: What is the background for this study? Response: Cannabis use carries risk for developing Type 2 diabetes.  It is important for physicians to screen for the use of cannabis to better understand each patients risk. MedicalResearch.com: What are the main findings? Response:  Clinically physicians should screen for and council on the risk of cannabis use. People should know what is the risk in the substances they use and make the choice that they feel is right. 
AI and HealthCare, Author Interviews, Cannabis, Pharmacology, Technology / 28.08.2025

[caption id="attachment_70470" align="alignleft" width="150"]Duncan Dobbins, PharmD, MHIGeisinger College of Health Sciences Scranton, Pennsylvania Dr. Dobbins, PharmD[/caption] MedicalResearch.com Interview with: Duncan Dobbins, PharmD, MHI Geisinger College of Health Sciences Scranton, Pennsylvania MedicalResearch.com: What prompted this commentary, and what did you find? Response: In theory, there could be a drug interaction between immunotherapy and medical cannabis. A small (N=102) observational report from Israel appeared to find that immunotherapies worked much less well in cancer patients who also used medical cannabis.1 However, a follow up report2 took about two weeks and involved manually rechecking the math and data-analysis. Several discrepancies emerged between the methods and results. Two-tailed tests were listed in the methods yet one-tailed p values appeared in the results. Arithmetic errors, some traceable to unconventional “floor” rounding, affected key percentages. Multiple p values in Table 1 (21 out of 22) could not be reproduced with the stated tests. Finally, smoking status, a key confound, was not reported. Taken together, these issues complicate interpretation and highlight how small computational slips can cascade into larger inferential uncertainty. For this follow-up report, I was asked, “Do you think AI could have double checked this math?”
Cannabis / 21.08.2025

Editor’ note:  Discuss your use of THC, Cannabis or CBD products with your health care provider.  Cannabis/CBD may interfere with other medications and should not be used in individuals with certain health conditions, including liver issues. CBD skin care products can be absorbed through the skin and have similar effects. Do not use Cannabis products including edibles and CBD if you are pregnant, nursing or may become pregnant. Do not use cannabis products if driving or operating difficult or dangerous machinery. Children should not be exposed to cannabis or CBD products. [caption id="attachment_70363" align="aligncenter" width="500"]bridge-between-medicine-cannabis Photo by MART PRODUCTION[/caption] The landscape of medical cannabis research is evolving rapidly, with new clinical studies emerging monthly that challenge long-held assumptions about cannabinoid therapy. As healthcare professionals navigate this complex field, the need for evidence-based information has never been more critical. Recent research developments are beginning to provide the scientific foundation that both patients and practitioners have been seeking. Current State of Clinical Research Medical cannabis research has accelerated significantly in recent years, with over 300 peer-reviewed studies published in 2024 alone. Key areas of investigation include chronic pain management, epilepsy treatment, cancer-related symptoms, and neurological disorders. The National Institutes of Health has increased funding for cannabinoid research by 40% since 2022, reflecting growing institutional recognition of therapeutic potential. Clinical trials are now examining specific cannabinoid ratios and their effects on various conditions. Research teams at major medical centers are particularly focused on understanding how different compounds interact with the endocannabinoid system and influence therapeutic outcomes.
Addiction, Cannabis, Pediatrics / 02.08.2025

[caption id="attachment_70143" align="alignleft" width="200"]Dr-Michael-S-Dunbar Dr. Dunbar[/caption] MedicalResearch.com Interview with: Michael S. Dunbar, PhD Senior Behavioral Scientist RAND MedicalResearch.com: What is the background for this study? Response: Cannabis products are way stronger, or more potent, today than they were 20 years ago. In the past few decades, average levels of THC (i.e., the main substance in cannabis that leads to feeling high) in cannabis products have risen dramatically. With cannabis becoming increasingly accessible in places like the U.S., health officials have raised questions about how higher-potency products might be associated with problematic cannabis use and related harms, including cannabis use disorder. This is especially important for at-risk groups like young adults, who tend to use cannabis at higher rates than other age groups. One perspective is that people may use high-potency products less frequently and/or in lower amounts (i.e., “titrate”), which could mitigate some potential risks. Alternatively, if people use higher-potency products more frequently or heavily, it may increase potential for harm. In this study, we looked at how use of higher-potency cannabis flower correlated with use behavior and symptoms of problematic cannabis use in a sample of young adults.
Author Interviews, Cannabis / 30.07.2025

As cannabis use becomes increasingly mainstream, many individuals are seeking healthier ways to consume it. While smoking remains the most traditional method, concerns about respiratory health and long-term effects have prompted users to explore alternatives. This article delves into the health implications of smoking, vaping, and other delivery methods, providing an evidence-based comparison to help consumers make informed decisions.

Understanding the Risks of Smoking Cannabis

Smoking cannabis involves combusting the plant material, which produces smoke containing not only cannabinoids like THC and CBD but also a variety of harmful byproducts. These include tar, carbon monoxide, and carcinogenic compounds similar to those found in tobacco smoke. Research indicates that regular cannabis smoking can lead to respiratory issues such as chronic bronchitis, coughing, and phlegm production. While cannabis smoke contains fewer carcinogens than tobacco smoke, it still poses risks to lung health. However, unlike tobacco, cannabis smoking has not been definitively linked to lung cancer, though the data remains inconclusive due to limited long-term studies. One major concern is the temperature at which cannabis is combusted, typically around 600–900°C, which generates numerous toxic compounds. Additionally, smoking delivers cannabinoids rapidly but can irritate the respiratory tract, making it less suitable for those with pre-existing lung conditions.
Cannabis / 28.07.2025

Editor's note: Discuss your use of THC, Cannabis or CBD products with your health care provider.  Dosing of CBD is variable, especially since it is not FDA regulated. Cannabis/CBD may interfere with other medications and should not be used in individuals with certain health conditions, including liver issues. CBD skin care products can be absorbed through the skin and have similar effects. Do not use Cannabis products including edibles and CBD if you are pregnant, nursing or may become pregnant. Do not use cannabis products if driving or operating difficult or dangerous machinery. Children should not be exposed to cannabis or CBD products. [caption id="attachment_70032" align="aligncenter" width="500"]Cannabinoids and Endocannabinoids Freepik image[/caption] The human body is a complex network of systems working harmoniously to maintain balance and health. One of the lesser-known but critically important systems is the endocannabinoid system (ECS). This intricate system plays a vital role in regulating a variety of physiological processes, including mood, pain sensation, appetite, and immune response. Central to the ECS are cannabinoids: both those produced naturally within the body and those introduced from external sources like cannabis. Understanding how cannabinoids interact with the endocannabinoid system is key to unlocking their therapeutic potential and appreciating their impact on human health.

What is the Endocannabinoid System?

The endocannabinoid system is a biological network found in all vertebrates, including humans. It consists primarily of three components:
  • Endocannabinoids
  • Cannabinoid receptors
  • Enzymes that synthesize and degrade endocannabinoids
Discovered in the early 1990s, the ECS has since been recognized as a crucial regulator of homeostasis—the body’s internal balance. Endocannabinoids are naturally occurring lipid-based neurotransmitters, the most well-known being anandamide and 2-arachidonoylglycerol (2-AG). These molecules bind to cannabinoid receptors, which are located throughout the body, including the brain, immune cells, organs, and connective tissues. The two primary receptors are CB1 and CB2, each with distinct functions and locations. CB1 receptors are predominantly found in the central nervous system, influencing memory, pain, and motor control, while CB2 receptors are mostly present in the peripheral nervous system and immune cells, modulating inflammation and immune responses.
Cannabis / 03.06.2025

Discuss your use of Cannabis, THC or CBD products with your health care provider.  Do not use Cannabis products including edibles, THC  and CBD if you are pregnant, nursing or may become pregnant. Do not use cannabis products if driving or operating difficult or dangerous machinery. Children should not be exposed to cannabis products

5 Things You Must Know Before Buying THC Drinks

 

THC drinks, the new vibe taking the beverage industry by storm. More partygoers and drinkers are embracing this new sip with zeal. It seems nothing beats the relaxing, social buzz that THC drinks offer. Of course, without having to worry about a punishing headache or  nasty hangovers the day after.

However, not all THC drinks are created equal. That means one thing. Diving in without the right knowledge can lead to a less-than-pleasant experience. What exactly should you know about THC drinks before taking a sip? That’s what this post is all about.

Here are five essential things you must know before buying THC drinks:.

Author Interviews, Cannabis, Heart Disease / 29.05.2025

MedicalResearch.com Interview with: [caption id="attachment_68847" align="alignleft" width="150"]Dr. Springer Dr. Springer[/caption] Matthew L. Springer, Ph.D. Associate Professor of Medicine Division of Cardiology Cardiovascular Research Institute Broad Center of Regeneration Medicine and Stem Cell Research Center for Tobacco Control Research & Education Helen Diller Family Comprehensive Cancer Center University of California, San Francisco MedicalResearch.com: What is the background for this study? Response: It's been known for many years that chronic tobacco smokers have poor endothelial function, even if they have not smoked recently, and so do non-smokers who are frequently exposed to secondhand smoke.  Endothelial dysfunction, even in otherwise outwardly healthy people, is an indication of unhealthy arteries and increased risk of cardiovascular disease later in life.  I realized that many people who would presumably avoid secondhand smoke did not mind it if it came from cannabis, and I wondered if that could be true since both kinds of smoke included the thousands of chemicals that resulted from burning plant material. A number of years ago, we developed a way to study changes in endothelial function in rats, using a technique very similar to how we measure it in humans, and we saw that, as in humans, even brief exposures to secondhand smoke from tobacco impaired vascular function in the rats.  We subsequently showed that brief exposures to secondhand smoke from marijuana, and active smoking of marijuana, similarly impaired vascular function in the rats, even if the smoke was from marijuana lacking THC and the other cannabinoids.  That again raised the question of whether the endothelial dysfunction observed in human tobacco smokers would also occur in human marijuana smokers, and whether secondhand smoke from marijuana should be avoided like secondhand smoke from tobacco. These questions form the basis of our current study..  In our study, it is quite clear that chronic cannabis smokers had endothelial dysfunction similar to that of chronic tobacco smokers.  Whether frequent exposure to secondhand marijuana smoke similarly impairs endothelial function like secondhand tobacco smoke is still unknown, and that's one of the major questions we want to answer next.
Cannabis / 26.05.2025

Discuss your use of Cannabis or CBD products with your health care provider.  Dosing of CBD is variable, especially since it is not FDA regulated. Cannabis/CBD may interfere with other medications and should not be used in individuals with certain health conditions, including liver issues. CBD skin care products can be absorbed through the skin and have similar effects. Do not use Cannabis products including edibles and CBD if you are pregnant, nursing or may become pregnant. Do not use cannabis products if driving or operating difficult or dangerous machinery. Children should not be exposed to cannabis or CBD products. [caption id="attachment_68779" align="aligncenter" width="320"]cbd-purchase-cannabis Photo by Binoid CBD[/caption] For consumers looking for natural substitutes, the growing industry for CBD (cannabidiol) products has presented a world of wellness options. Accessing a large range of CBD oils and topicals has been easier due to the simplicity of online buying. However, consumers have to act to guarantee that the CBD products they purchase online are safe, premium, and powerful. Negotiating the huge digital market requires both a discriminating eye and a proactive strategy. This ultimate guide will offer basic advice and a methodical approach to enable customers to make wise choices when shopping for CBD products online. Prioritize transparency Transparency, more especially, by confirming the presence of thorough third-party lab testing, should be the most important advice for safe and wise CBD purchases online. Reputable CBD brands will provide access to thorough lab results by verifying the strength, purity, and safety of their goods. When considering CBD Products For Sale Online, confirm the right dosage of CBD and other cannabinoids.
Cannabis / 20.05.2025

Editor's note:Discuss your use of Cannabis or CBD products with your health care provider.  Dosing of CBD is variable, especially since it is not FDA regulated. Cannabis/CBD may interfere with other medications and should not be used in individuals with certain health conditions, including liver issues. CBD skin care products can be absorbed through the skin and have similar effects. Do not use Cannabis products including edibles and CBD if you are pregnant, nursing or may become pregnant. Do not use cannabis products if driving or operating difficult or dangerous machinery. Children should not be exposed to cannabis or CBD products. [caption id="attachment_68629" align="aligncenter" width="500"]technologies-growing-medical-marijuana Photo by Washarapol D BinYo Jundang[/caption] The medical marijuana industry is growing quickly, thanks to new technology. These advancements are improving how cannabis is grown, how patients access it, and how products are made. As more states expand their medical marijuana programs, technology is making it easier for patients to get high-quality medical cannabis in a safe and reliable way. See how new tech impacts medical marijuana at TeleLeaf.
Cannabis, Epilepsy, Pain Research / 18.05.2025

Discuss your use of Cannabis or CBD products with your health care provider.  Dosing of CBD is variable, especially since it is not FDA regulated. Cannabis/CBD may interfere with other medications and should not be used in individuals with certain health conditions, including liver issues. CBD skin care products can be absorbed through the skin and have similar effects. Do not use Cannabis products including edibles and CBD if you are pregnant, nursing or may become pregnant. Do not use cannabis products if driving or operating difficult or dangerous machinery. Children should not be exposed to cannabis or CBD products. [caption id="attachment_68597" align="aligncenter" width="500"]medical-marijuana-ohio-dispensaries Photo by RDNE Stock project[/caption] Ohio’s medical marijuana program offers qualifying patients safe, state-regulated access to cannabis products for symptom relief and improved quality of life. Established by House Bill 523 in 2016, the Ohio Medical Marijuana Control Program (OMMCP) began licensed sales at dispensaries on January 16, 2019, under strict rules designed to protect patients and ensure product safety. Patients receive physician-certified cards from the Ohio Board of Pharmacy, allowing them to purchase low-THC or high-CBD products in non-smoking forms—only edibles, oils, vapors, patches, tinctures, or plant matter. Qualifying Conditions To be eligible, patients must have at least one of the 21 state-approved conditions. The original qualifying conditions include:
  • Acquired immune deficiency syndrome (AIDS/HIV)
  • Alzheimer’s disease
  • Amyotrophic lateral sclerosis (ALS)
  • Cancer
  • Chronic traumatic encephalopathy (CTE)
  • Crohn’s disease
  • Epilepsy or other seizure disorders
  • Fibromyalgia
  • Glaucoma
  • Hepatitis C
  • Inflammatory bowel disease (including Crohn’s or ulcerative colitis)
  • Multiple sclerosis
  • “Chronic and severe or intractable” pain
  • Parkinson’s disease
  • Post-traumatic stress disorder (PTSD)
  • Sickle cell anemia
  • Spinal cord disease or injury
  • Tourette’s syndrome
  • Traumatic brain injury (TBI)
  • Ulcerative colitis
  • Any other condition added by the State Medical Board of Ohio
Author Interviews, Cannabis, Colon Cancer, UCSD / 30.04.2025

MedicalResearch.com Interview with: [caption id="attachment_68230" align="alignleft" width="150"]Raphael E. Cuomo, PhD, MPH, CPH, FRSPHProfessor, School of Medicine University of California, San Diego Dr. Cuomo[/caption] Raphael E. Cuomo, PhD, MPH, CPH, FRSPH Professor, School of Medicine University of California, San Diego MedicalResearch.com: What is the background for this study? Response: Colon cancer remains a leading cause of cancer-related death worldwide. Recent years have seen a substantial increase in cannabis use, but limited research has explored its potential influence on cancer outcomes. We conducted a large-scale retrospective cohort study using real-world clinical data to investigate whether a diagnosis of cannabis use disorder prior to colon cancer diagnosis was associated with survival outcomes.
Cancer Research, Cannabis, Neurological Disorders, Pain Research / 16.04.2025

Editor’ note:  Cannabis and THCA/HEMP CBD products should have an active ingredient list on the container and have a Certificate of Analysis (COA).  Discuss your use of CBD products with your health care provider.  Dosing of CBD is variable, especially since it is not FDA regulated. CBD may interfere with other medications and should not be used in individuals with certain health conditions, including liver issues. CBD skin care products can be absorbed through the skin and have similar effects. Do not use Cannabis products including edibles and CBD if you are pregnant, nursing or may become pregnant. Do not use cannabis products if driving or operating difficult or dangerous machinery. [caption id="attachment_67969" align="aligncenter" width="500"]painful-feet-neuropathy-cbd Photo by Towfiqu barbhuiya[/caption]  You fight through the appointments, the scans, the treatments, and then—when it’s supposed to be over—your body still feels off. For many cancer survivors, especially those who went through chemotherapy, neuropathy doesn’t just fade away. Sometimes it lingers, sometimes it gets worse, and sometimes it shows up in ways that completely change how you move. If you’re dealing with drop foot or numbness, burning, or pain in your feet, you’re not imagining it. You’re not alone. And while it’s incredibly frustrating, there are real things that can help. Understanding What’s Happening To Your Feet Post-cancer neuropathy isn’t just annoying—it can be debilitating. It usually starts because certain chemo drugs damage the nerves, especially in your hands and feet. This damage can mess with how your muscles and nerves talk to each other. So when your brain says “lift your foot,” your body doesn’t always get the message right. Drop foot is one of the more obvious results of that disconnect. It feels like your foot is dragging or slapping the ground when you walk. You might start tripping more, feel unsteady, or start avoiding certain shoes altogether. For others, the issue isn’t how the foot moves but how it feels—like walking on pins and needles, or not feeling it at all. Both are forms of neuropathy, and both can stick around long after treatment ends. The tricky part is that this isn’t something you can just walk off. It’s not about needing to stretch more or push harder. These symptoms come from actual nerve damage, which doesn’t always heal quickly—or fully.
Author Interviews, Cannabis, Medical Imaging, OBGYNE, Pediatrics / 10.04.2025

MedicalResearch.com Interview with: [caption id="attachment_67865" align="alignleft" width="200"]Sam (Seyedmehdi) Payabvash, MD Associate Professor of Radiology  Columbia University Medical Center Dr. Payabvash[/caption] Sam (Seyedmehdi) Payabvash, MD Associate Professor of Radiology Columbia University Medical Center MedicalResearch.com: What is the background for this study? Response: Prenatal marijuana use is on the rise, largely due to increasing legalization and shifting public perception of its safety during pregnancy. Although prior studies have linked prenatal marijuana exposure to adverse neonatal and behavioral outcomes, the long-term neurodevelopmental effects, especially as assessed through advanced neuroimaging techniques, remain underexplored.
Author Interviews, Cannabis, Pediatrics / 26.03.2025

[caption id="attachment_67574" align="aligncenter" width="500"]woman-smoking-marijuana-cannabis Image source[/caption] MedicalResearch.com Interview with: Mr. Abay Tadesse,  PhD candidate School of Population Health Curtin University Australia MedicalResearch.com: What is the background for this study? Response: Few studies have investigated the association between maternal gestational cannabis use and the risk of disruptive behavioural disorders (DBDs) in offspring. Small sample sizes, reliance on self-reported data and focus on solely in-utero exposure often limit existing research, leading to inconsistent findings. Given the increasing prevalence of cannabis use during pregnancy, there is an urgent need for robust, population-based evidence to better understand its potential impact on child neurobehavioral outcomes. This study aimed to examine the relationship between maternal cannabis use disorder (CUD) during pregnancy and postpartum periods and the risk of DBDs in offspring. Using linked health data from New South Wales, Australia, we conducted a population-based retrospective cohort study of live births between 2003 and 2005.
Cannabis, Pain Research / 24.03.2025

MedicalResearch.com Interview with: [caption id="attachment_67515" align="alignleft" width="200"]John M. Streicher, PhD Professor, Neuroscience - GIDP Professor, Pharmacology College of Medicine Tucson Pharmacology University of Arizona Dr. Streicher[/caption] John M. Streicher, PhD Professor, Neuroscience - GIDP Professor, Pharmacology College of Medicine Tucson Pharmacology University of Arizona   MedicalResearch.com: What is the background for this study? Response: We first started studying terpenes around 2019, when my student Justin LaVigne became interested in these molecules and their potential interaction with cannabinoids and other chemicals in cannabis, the so-called “entourage effect.” The literature at the time showed that terpenes could be beneficial in pain relief and other indications, in both animal and human studies; however, there were limits to the literature, such as a lack of investigation into therapeutic features like side effects and a relative lack of detailed molecular mechanisms. We started by testing 5 purified terpenes in mice, geraniol, linalool, beta-caryophyllene, alpha-humulene, and beta-pinene. We found they had a “cannabimimetic” effect in that they produced behaviors much like cannabinoids, but not through the cannabinoid receptors. This was published in 2021.
Cannabis / 06.03.2025

Editor’ note:  Cannabis and THCA/HEMP CBD products should have an active ingredient list on the container and have a Certificate of Analysis (COA) Discuss your use of CBD products with your health care provider.  Dosing of CBD is variable, especially since it is not FDA regulated. CBD may interfere with other medications and should not be used in individuals with certain health conditions, including liver issues. CBD skin care products can be absorbed through the skin and have similar effects. Do not use marijuana or cannabis products including edibles and CBD if you are pregnant, nursing or may become pregnant. Do not use cannabis products if driving or operating difficult or dangerous machinery. Children should not be exposed to marijuana, cannabis or CBD products. [caption id="attachment_67028" align="aligncenter" width="500"]rise of natural compounds.jpg Pexels.com [/caption] With more people's attention turning to natural solutions for health and leisure, the wellness sector has experienced a wonderful metamorphosis lately. Many people would rather avoid the negative effects of conventional medications, even if they are effective. Thus, natural chemicals from plants and other organic sources have become somewhat well-known. These substances provide a holistic approach to wellness, enabling people to keep balance in their mental and physical condition.  Plant-based cannabinoids are one especially interesting class of natural wellness remedies. Nowadays, consumers seeking substitutes for traditional choices go to HHC flower products online for their daily wellness regimen. For individuals looking for a more natural route to well-being, these products offer relaxing advantages free from the strong effects linked with other substances. These natural substitutes are fast going mainstream as accessibility rises, and more evidence supports their efficacy. 
Author Interviews, Cannabis / 27.02.2025

MedicalResearch.com Interview with: [caption id="attachment_66863" align="alignleft" width="200"]Elena Stains Elena Stains[/caption] Elena Stains Medical Student Department of Medical Education Geisinger Commonwealth School of Medicine Scranton, PA MedicalResearch.com: What is the background for this study? Response: In 2019 to 2020, 2.5% of Americans reported using cannabis for medical needs, compared to 1.2% in 2013-2014, representing a 12.9% annual increase1. Forty states and the District of Columbia have legislation for some form of medical cannabis (MC) in 2024. Because MC is not federally legalized, each state creates its own legislation on the conditions that qualify a person for MC, without any standardized process to determine what qualifying conditions (QC) are proven to be aided by MC. Thus, the QCs chosen by states vary widely. Common QCs include cancer, dementia, and PTSD. The National Academies of Sciences, Engineering, and Medicine (NAS) published a report in 2017 on the evidence for the therapeutic effects of cannabis and cannabinoids for over twenty conditions2. This report reviews the evidence of effectiveness of medical cannabis for the most common QCs chosen by states. The researchers at Geisinger Commonwealth School of Medicine aimed to compare the evidence found by the NAS report with the QCs of 38 states (including the District of Columbia) in both 2017 and 2024. QCs were categorized based on NAS-established level of evidence: limited, moderate, or substantial/conclusive evidence of effectiveness, limited evidence of ineffectiveness, or no/insufficient evidence to support or refute effectiveness (Table 1).
Cannabis, Pain Research / 13.02.2025

Editor’ note:  Cannabis and THCA/HEMP CBD products should have an active ingredient list on the container and have a Certificate of Analysis (COA). Discuss your use of CBD products with your health care provider.  Dosing of CBD is variable, especially since it is not FDA regulated. CBD may interfere with other medications and should not be used in individuals with certain health conditions, including liver issues. CBD skin care products can be absorbed through the skin and have similar effects. Do not use Cannabis products including edibles and CBD if you are pregnant, nursing or may become pregnant. Do not use cannabis products if driving or operating difficult or dangerous machinery. Children should not be exposed to cannabis or CBD products. [caption id="attachment_66542" align="aligncenter" width="500"]medical-cannabis-for-pain Photo by Michael Fischer on Pexels[/caption] Medicinal cannabis is a revolutionary approach to pain management, particularly in patients where conventional medications fail to offer them adequate relief or create intolerable side effects. With ongoing research on cannabis and its medicinal properties, its effectiveness for pain relief has become more convincing. Here are some reasons why medicinal cannabis has risen in popularity in pain management.

Natural Pain Relief Without Risks from Opioids

Many countries have been grappling with an opioid crisis, which has motivated patients to seek cannabis as a much safer alternative. Medicinal cannabis minimizes the risks of addiction associated with opioids due to misuse and gives little risk of an overdose. To obtain medicinal cannabis legally, there are options like medical marijuana cards you can obtain from providers such as Leafy Doc Mississippi. Regarding how cannabis works in terms of pain relief, cannabinoids like THC bind to receptors in the brain and the immune system, modulating the experience of pain. The endocannabinoid system engages with trauma states mainly on account of pain, mood regulation, and inflammation. However, for long-term relief, medicinal cannabis is viewed as a considerably safer alternative compared to opioids.
Author Interviews, Cannabis, JAMA, Pediatrics, UCSD / 30.01.2025

MedicalResearch.com Interview with: [caption id="attachment_66243" align="alignleft" width="150"]John Bellettiere, PhDAssistant Adjunct Professor Herbert Wertheim School of Public Health & Human Longevity Science University of California, San Diego Dr. Bellettiere[/caption] John Bellettiere, PhD Assistant Adjunct Professor Herbert Wertheim School of Public Health & Human Longevity Science University of California, San Diego MedicalResearch.com: What is the background for this study? Response:  Smoking is the most common method of cannabis use and generates harmful emissions.  Cannabis is often smoked indoors, which exposes non-smokers, including children, to these emissions. Our research analyzed in-home cannabis smoking practices to determine if there is an association between this behavior and the detection of cannabis biomarkers in children.
Author Interviews, Cannabis, Cognitive Issues, JAMA, Memory, Mental Health Research / 28.01.2025

MedicalResearch.com Interview with: [caption id="attachment_66219" align="alignleft" width="200"]Joshua Gowin PhDAssistant Professor, Radiology Anschutz Medical Campus University of Colorado  Dr. Gowin[/caption] Joshua Gowin PhD Assistant Professor, Radiology Anschutz Medical Campus University of Colorado  MedicalResearch.com: What is the background for this study? Response: Many people want to know how cannabis affects their brain and cognitive abilities. Previous studies have shown that cannabis use can impair learning and verbal memory function. Some evidence has shown that cannabis use is associated with smaller volume of areas of the prefrontal cortex. Our study investigated how cannabis use is associated with brain function. We examined brain function across 7 tasks in 1,000 adults. 88 of them had used cannabis over 1,000 times in their lives.
Cannabis / 26.01.2025

Editor’ note:  Cannabis and THCA/HEMP CBD products should have an active ingredient list on the container and have a Certificate of Analysis (COA). Discuss your use of CBD products with your health care provider.  Dosing of CBD is variable, especially since it is not FDA regulated. CBD may interfere with other medications and should not be used in individuals with certain health conditions, including liver issues. CBD skin care products can be absorbed through the skin and have similar effects. Do not use Cannabis products including edibles and CBD if you are pregnant, nursing or may become pregnant. Do not use cannabis products if driving or operating difficult or dangerous machinery. Children should not be exposed to cannabis or CBD products. potential-benefits-cannabis.png CBD and cannabis have been at the center of much talk about their therapeutic potential in recent years. As the benefits of these natural compounds become unveiled through more research, more individuals embrace them as a natural remedy for various health conditions. Once shrouded with different misconceptions, the medical community is exploring CBD and cannabis because of their potential effects on the body and mind. This article discusses the science behind these compounds, highlighting potential advantages while considering the role they can play in promoting health and well-being.
Author Interviews, Cannabis, JAMA / 25.01.2025

MedicalResearch.com Interview with: [caption id="attachment_66106" align="alignleft" width="200"]Silvia S. Martins, MD, PhDAssociate Dean for Faculty Professor of Epidemiology Director, Substance Use Epidemiology Unit Co-Director, Substance Abuse Epidemiology T32 Program Department of Epidemiology Columbia University Mailman School of Public Health New York, NY Dr. Martins[/caption] Silvia S. Martins, MD, PhD Associate Dean for Faculty Professor of Epidemiology Director, Substance Use Epidemiology Unit Co-Director, Substance Abuse Epidemiology T32 Program Department of Epidemiology Columbia University Mailman School of Public Health New York, NY MedicalResearch.com: What is the background for this study? Response: Much has been speculated on whether the enactment of medical and recreational cannabis laws can have a role in decreasing prescriptions for opioid pain relievers, opioid use and misuse, opioid use disorder, and overdose in the U.S. However, findings on the associations of medical cannabis laws alone and recreational cannabis las + medical cannabis laws with opioid-related outcomes are mixed. By the end of 2019, 32 U.S. states had adopted medical marijuana laws (MCL) alone. All states that went on to adopt recreational marijuana laws (RCL) had previously adopted an MCL.
Author Interviews, Cannabis / 15.01.2025

MedicalResearch.com Interview with: Vishal A Shetty, MS, PhD Candidate Center for Pharmacy and Innovation Outcomes, Geisinger University of Massachusetts AmherstVishal A Shetty, MS, PhD Candidate Center for Pharmacy and Innovation Outcomes, Geisinger University of Massachusetts Amherst MedicalResearch.com: What is the background for this study? Response: With more U.S. states moving toward the legalization of medical and recreational cannabis, recent studies have explored electronic health record (EHR) documentation to understand the nature of cannabis use among patient populations. However, these efforts have not been extended to patient portal messaging, which allows patients to describe health-related behaviors in ways that may not be sufficiently captured in standard EHR documentation. The primary objective of this study was to identify patient and provider secure messages that discussed cannabis and contextualize these discussions over periods prior to and after its legalization for medical purposes in Pennsylvania.