Author Interviews, Infections / 12.03.2026
Vanderbilt Physician Discusses Newly Recognized and Contagious Human Metapneumovirus
MedicalResearch.com Interview with:
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Dr. Schaffner[/caption]
Dr. William Schaffner M.D.
Professor of Medicine
Preventive Medicine, Health Policy
Division of Infectious Diseases
Vanderbilt University School of Medicine
Interview arranged with the assistance of the Infectious Disease Society of America.
MedicalResearch.com: What are the symptoms of HMPV? How is it transmitted? Are some individuals more susceptible to infection or more serious disease?
Response: Human metapneumovirus (HMPV) is a seasonal respiratory virus that has a worldwide distribution, causing late winter/early spring outbreaks in temperate zones. It cocirculates with other seasonal respiratory viruses including influenza, COVID, and RSV. Virtually all children have experienced infection by age 5; persons experience HMPV reinfections throughout life. The virus is transmitted through close personal contact, most efficiently indoors. Infection with HMPV can produce a spectrum of clinical symptoms ranging from a common cold to acute respiratory distress. Persons at increased risk of severe disease include older persons and those with chronic medical conditions.
Dr. Schaffner[/caption]
Dr. William Schaffner M.D.
Professor of Medicine
Preventive Medicine, Health Policy
Division of Infectious Diseases
Vanderbilt University School of Medicine
Interview arranged with the assistance of the Infectious Disease Society of America.
MedicalResearch.com: What are the symptoms of HMPV? How is it transmitted? Are some individuals more susceptible to infection or more serious disease?
Response: Human metapneumovirus (HMPV) is a seasonal respiratory virus that has a worldwide distribution, causing late winter/early spring outbreaks in temperate zones. It cocirculates with other seasonal respiratory viruses including influenza, COVID, and RSV. Virtually all children have experienced infection by age 5; persons experience HMPV reinfections throughout life. The virus is transmitted through close personal contact, most efficiently indoors. Infection with HMPV can produce a spectrum of clinical symptoms ranging from a common cold to acute respiratory distress. Persons at increased risk of severe disease include older persons and those with chronic medical conditions.
Candida auris CDC Image[/caption]
MedicalResearch.com Interview with:
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Dr. Schaffner[/caption]
William Schaffner, MD
MedicalResearch.com: What roles do a decrease in US immunization rates and/or increased immigration from under-vaccinated area play in this increase?
Response: The substantial majority of unimmunized children in the US were born and raised in this country. They usually are members of middle- or upper-income families. The most frequent importers of measles into the US are our own unimmunized children who travel abroad, encounter measles virus and bring it back to their homes where the virus then spreads among the child’s schoolmates and playmates, creating an outbreak.
Dr. Freedman M.D.[/caption]
David O. Freedman, M.D.
Professor Emeritus of Infectious Diseases
Editor of the Textbook of Travel Medicine
World Health Organization—Member, Emergency Committee on Zika Virus
University of Alabama, Birmingham USA
MedicalResearch.com: What is the background for this outbreak?
Response: India has reported 2 confirmed (PCR and ELISA) Nipah virus (NiV) cases in West Bengal State where the Kolkata megalopolis is located; the state borders Bangladesh. Symptom onset in both cases was late December 2025 in 2 health care workers. One patient has improved while the other remains in the ICU. All samples from 200 contact persons tested negative for NiV. No further confirmed cases have been detected in West Bengal
Bangladesh has reported 1 confirmed NiV case in Rajshahi Division which neighbors India. Symptom onset was January 21, 2026, and the patient expired on January 28. The patient reported no travel history but reported repeated consumption of raw date palm sap between 5 and 20 January. All 35 contact-persons are being monitored and have tested negative for NiV and no further cases have been detected to date.
Dr. Dehghani[/caption]
MedicalResearch.com Interview with:
Ali Dehghani, DO
Department of Medicine
University Hospitals Cleveland Medical Center / Case Western Reserve University
Presenting Author, IDWeek 2025
MedicalResearch.com: What is the background for this study?
Response: Shingles (herpes zoster) is caused by reactivation of the varicella-zoster virus, which can inflame blood vessels and the nervous system. Evidence over the past decade has linked shingles to higher risks of heart attack, stroke, and dementia—but it was unclear whether the shingles vaccine might lessen those long-term effects.
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Dr. Bradshaw[/caption]
Catriona Bradshaw MMBS(Hons), PhD, FAChSHM, FAHMS
Professor (Research), Head of Research Translation and Mentorship
and of The Genital Microbiota and Mycoplasma Group Melbourne
School of Translational Medicine, Monash University and Alfred Hospital
Principal Research Fellow at the Burnet Institute
MedicalResearch.com: What is the background for this study?
Response: One in three women globally have bacterial vaginosis (BV), a condition that causes a malodourous discharge, and associated with serious gynaecologic and obstetric sequelae (including miscarriage and preterm birth) and increases the risk sexually transmitted infections (STIs) and HIV. Women with symptoms are treated with broad-spectrum antibiotics, however, over 50% of women experience BV recurrence within 3-6 months. The recurrence rate is even higher at 60-80% among women with an ongoing regular partner. Current practice is to simply retreat women experiencing BV recurrence with the same antibiotics, which leaves them (and clinicians) frustrated and distressed.
We and others have accumulated a body of evidence to show that BV has the profile of an STI. BV-associated bacteria are detected in men in the distal urethra and on penile-skin, and couples share these organisms. However, to date, has not been recommended for BV as it is for other STIs. This is largely because men do not usually have any symptoms, and past partner-treatment trials in the 1980s and 1990s, which only used oral antibiotics for men, failed to prevent BV recurrence, which was taken as conclusive evidence against sexual transmission. Reviews of these trials have since identified their limitations.
Given the evidence of male carriage of BV-associated bacteria at two genital sites, we hypothesised that both sites needed to be targeted with antimicrobial therapy to prevent re-infection post-treatment. The aim of our study was to assess if male partner-treatment concurrently with female treatment using a combination of oral and topical antibiotics for the first time, would decrease BV recurrence over 12 weeks compared to the current standard practice of treating women only.
Prof. Chaturvedi[/caption]
Prof. Vishnu Chaturvedi, Ph.D., HCLD
Department of Pathology, Microbiology and Immunology
New York Medical College
Department of Pathology, Westchester Medical Center
Valhalla, New York,
MedicalResearch.com: What is the background for this study? How does Candida auris differ from Candida albicans, ie in clinical presentation or treatment?
