Paper and Digital SAGE Brain Tests Equally Identify Cognitive Impairment and Dementia

MedicalResearch.com Interview with:

Douglas W. Scharre MD Professor of Clinical Neurology and Psychiatry Director Division of Cognitive Neurology, Department of Neurology  Director, Center for Cognitive and Memory Disorders Director, Memory Disorders Research Center Co-Director, Neuroscience Research Institute Ohio State University Wexner Medical Center  Columbus, OH

Dr. Douglas Scharre

Douglas W. Scharre MD
Professor of Clinical Neurology and Psychiatry Director, Division of Cognitive Neurology
Department of Neurology
Director, Center for Cognitive and Memory Disorders
Director, Memory Disorders Research Center
Co-Director, Neuroscience Research Institute
Ohio State University Wexner Medical Center
Columbus, OH

 

MedicalResearch.com: What is the background for this study? What are the main findings?

Response: Self-Administered Gerocognitive Examination (SAGE) is a pen-and paper, valid and reliable cognitive assessment tool for identifying individuals with mild cognitive impairment (MCI) or early dementia. We published age and education normative data on SAGE and determined that one point be added to the scores when age over 79 and one point be added when education level is 12 years or less. We evaluated the identical test questions in digital format (eSAGE) made for tablet use, adjusted with previously published age and education norms, and determined eSAGE’s association with gold standard clinical assessments. eSAGE is commercially known as BrainTest.

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Mixed and Augmented Reality Can Facilitate Seamless Medical Communication

MedicalResearch.com Interview with:

Dr Ian Williams PhD Associate Professor, DMT Lab Birmingham City University Faculty of Computing, Engineering and the Built Environment Centre for Digital Media Technology Millennium Point Birmingham UK

Dr. Williams

Dr Ian Williams PhD
Associate Professor, DMT Lab
Birmingham City University
Faculty of Computing, Engineering and the Built Environment
Centre for Digital Media Technology
Millennium Point
Birmingham UK

MedicalResearch.com: What is the background for your work?

Response: Our work at the DMT Lab (dmtlab.bcu.ac.uk) focuses on developing a novel Mixed Reality (MR) medical presentation platform which allows practitioners to interact with patient data and virtual anatomical models in real time. The system enables the presentation of medical data, models and procedures to patients with the aim of educating them on pending procedures or the effects of lifestyle choices (for example the effects of smoking or excessive alcohol consumption).

The system employs an exocentric mixed reality environment which can be deployed in any room. It integrates a medical practitioner in real time with multimodal patient data and the corresponding result is a real time co-located visualisation of both the practitioner and the data, which they can interact with in real time.  We implement a natural interaction method into the system which improves a user’s level of direct interaction with the virtual models and provides a more realistic control of the data.

The system can also be used in a fun educational setting where patients, students, children or any naive user, can learn about medical anatomical information via a real-time interactive mixed reality “body scanner”. This fun system overlays the MR information onto their own body in real-time and shows them scaled and interactive virtual organs, anatomy and corresponding medical information. We are aiming for this system to be used not only in patient education but also in engaging and informing people on lifestyle choices.

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Novo Nordisk and Glooko Launch Cornerstones4Care® App To Help Manage Diabetes

MedicalResearch.com Interview with:

David Moore MBA Senior Vice President of Marketing Novo Nordisk 

David Moore

David Moore MBA
Senior Vice President of Marketing
Novo Nordisk 

MedicalResearch.com: What is the Cornerstones4Care Powered by Glooko (C4C) App?

Response: The Cornerstones4Care® Powered by Glooko® App marries Novo Nordisk’s extensive knowledge of diabetes and personalized patient support with Glooko’s digital platform and data analytics expertise. The App is comprehensive tool that helps patients track meals, activity, medicine and blood sugar – in one convenient place – and is intended to help people learn how to better manage diabetes through their mobile devices.

MedicalResearch.com: What functions will people with diabetes have access to? How can the app help people living with diabetes control their disease?   

Response: The Cornerstones4Care® Powered by Glooko® App marries Novo Nordisk’s extensive knowledge of diabetes and personalized patient support with Glooko’s digital platform and data analytics expertise. The App is comprehensive tool that helps patients track meals, activity, medicine and blood sugar – in one convenient place – and is intended to help people learn how to better manage diabetes through their mobile devices.

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Pokémon Go! Promotes Walking and Decreases Sitting Time

MedicalResearch.com Interview with:

Jacob Barkley, Ph.D., College of Education, Health and Human Services Kent State

Dr. Barkley

Jacob Barkley, Ph.D.,
College of Education, Health and Human Services
Kent State 

MedicalResearch.com: What is the background for this study?

Response: Our group has demonstrated that cellular telephone (cell phone) use is positively associated with sedentary behavior (i.e., sitting). To that end, high cell phone users sit for 80 to 100 minutes longer than their lower-use peers. We have also shown that cell phone use during exercise decreases exercise intensity and slows free-living walking speed. In other words, cell use may be comparable to traditional sedentary screen use in that it promotes sitting and may interfere with physical activity. However, some cell phone functions may actually promote positive health behaviors.

Fitness apps, connecting with active peers and administering health recommendations via the cell phone all may have utility in promoting physical activity and reducing sedentary behavior. While not well studied, novel physically-interactive cell phone games may also promote physical activity. One such game, Pokémon Go! requires users to walk through real environments and locate avatars in the game using GPS. The purpose of the game is to find these avatars. In order to find more avatars, the player will need to walk to more areas. Therefore, playing Pokémon Go! may promote walking.

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Self Driving Cars Can Be Programmed To Make Moral Decisions

MedicalResearch.com Interview with:
Leon Sütfeld
The Institute of Cognitive Science
University of Osnabrück 

MedicalResearch.com: What is the background for this study? What are the main findings?

Response: Self-driving cars, and especially future fully autonomous cars, pose a number of ethical challenges. One of these challenges is making the “right” decision when it comes to a so-called dilemma situation, in which a collision is unavoidable (or highly probable), but a decision can be made as to which of multiple different collisions to choose. Our study assesses the behavior of human participants in such dilemma situations and evaluates algorithmic models that are trained on this data to make predictions.

Our main findings are that in a controlled virtual reality environment, the decisions of humans are fairly consistent and can be well described by simple value-of-life models.

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Refined Deep Brain Stimulation Turns On ‘As Needed’ To Treat Tremors

MedicalResearch.com Interview with:

Howard Jay Chizeck ScD Professor, Electrical Engineering Adjunct Professor, Bioengineering Co-Director UW Biorobotics Laboratory Graduate Program in Neuroscience UW CoMotion Presidential Innovation Fellow Research Thrust Testbed Co-Leader

Prof. Chizeck

Howard Jay Chizeck ScD
Professor, Electrical Engineering
Adjunct Professor, Bioengineering
Co-Director UW Biorobotics Laboratory
Graduate Program in Neuroscience
UW CoMotion Presidential Innovation Fellow
Research Thrust Testbed Co-Leader

MedicalResearch.com: What is the background for this study? What are the main findings?

Response: Essential Tremor is treated using Deep Brain Stimulation (DBS) in some patients. Current clinical practice involves Deep Brain Stimulation with an “always on” stimulation. This causes extra battery drain, because stimulation is applied when not needed. Also excessive stimulation is not necessarily a good thing,

Our work is aimed at adjusting the stimulation, so that it comes on and turns off only when needed to suppress tremor symptoms.

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Dissolvable Microneedle Patches Can Be Vaccination Game Changer

MedicalResearch.com Interview with:
Dr Nadine G Rouphael MD
Associate Professor of Medicine, Emory University
Director of the VTEU and HIPC networks at the
Hope Clinic of the Emory Vaccine Center
Decatur GA 30030, USA

MedicalResearch.com: What is the background for this new technology and study? What are the main findings?

Response: Different groups including a group of researchers at Georgia Tech have been working on the microneedle technology for more than 20 years. The dissolvable microneedle patches are already used in several cosmetic products and drugs. However, vaccination with microneedle patches has been studied mostly in animals.

Our phase 1 trial published this week in The Lancet showed that vaccination with the microneedle patches was safe, with no related serious adverse events reported. Local skin reactions to the patches were mostly mild itching and faint redness that lasted two to three days. No new chronic medical illnesses or influenza-like illnesses were reported with either the patch or the injection groups. Antibody responses generated by the vaccine, as measured through analysis of blood samples, were similar in the groups vaccinated using patches and those receiving intramuscular injection, and these immune responses were still present after six months. When asked after immunization, more than 70 percent of patch recipients reported they would prefer patch vaccination over injection or intranasal vaccination for future vaccinations.

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Lost Your Connection? Internet Withdrawal Can Mirror Addiction Symptoms

MedicalResearch.com Interview with:

Dr. Phil Reed,  D.Phil. Professor Psychology Swansea University

Dr. Reed

Dr. Phil Reed,  D.Phil.
Professor Psychology
Swansea University

MedicalResearch.com: What is the background for this study? What are the main findings?

Response: Problematic internet use has been a growing concern for many people and bodies over the last decade, and more study has been requested into various aspects of this possible disorder.  One of the key questions is whether people overuse the internet, due to an addiction.  If it is an addiction, then there should be signs of withdrawal when people, who report having this problem, stop using the internet.  In this study, 144 participants, aged 18 to 33, had their heart rate and blood pressure measured before and after a brief internet session.  Their anxiety and self-reported internet addiction were also assessed.

The results showed increases in heart rate and systolic blood pressure on terminating the internet session for those with problematically-high internet usage.  These increases in physiological arousal were mirrored by increased feelings of anxiety.  However, there were no such changes for those participants who reported no internet-usage problems.

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Engineering New Vasculature Could Revolutionize Root Canal Surgery

MedicalResearch.com Interview with:
Avathamsa Athirasala, MSE and
Luiz E. Bertassoni, DDS PhD

Biomaterials and Biomechanics, School of Dentistry
Center for Regenerative Medicine, School of Medicine
Biomedical Engineering, School of Medicine
Portland OR 97201 USA

MedicalResearch.com: What is the background for this study? What are the main findings?

Response: Current clinical practices for root canal treatment involve replacing the damaged tissue with inert, synthetic materials. While these procedures are able to arrest infection and decay in the tooth, they do not restore its biological function causing it to become weaker and more prone to fractures.

We are focused on the regeneration of pulp tissue instead and in this study, we have developed a strategy to apply tissue-engineering concepts to engineer dental pulp-like tissue constructs, complete with blood vessels, which can, in principle, integrate with existing vasculature when introduced at the site of injury and form healthy pulp tissue. Continue reading

AEDs Delivered By Drones May Improve Cardiac Arrest Survival

MedicalResearch.com Interview with:
“drones” by Andrew Turner is licensed under CC BY 2.0Andreas Claesson, RN, Paramedic

PhD Centre for resuscitation science
Karolinska institute
Stockholm, Sweden.

MedicalResearch.com: What is the background for this study? What are the main findings?

Response: Survival from out-of-hospital cardiac arrest is low, the technology is existing. When implementing this kind of system with a drone equipped with an AED, defibrillation may occur at an early stage and before EMS arrival mainly in rural areas.

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