Author Interviews, Psychological Science, Technology / 23.11.2017

MedicalResearch.com Interview with: “FACEBOOK(LET) Front” by FACEBOOK(LET) is licensed under CC BY 2.0Phillip Ozimek M.Sc. Department of Social Psychology Faculty of Psychology Ruhr-University Bochum UniversitätsstrBochum, Germany MedicalResearch.com: What is the background for this study? Response: We started reading the classic book by Erich Fromm „To have or to be“ out of personal interest. I was very much interested in studying social media, so we wondered how materialists would use facebook. After all Facebook seemed to be a perfect tool for people who love social comparisons. Furthermore, Facebook is for free – materialists love tools that do not cost money! (more…)
Author Interviews, Heart Disease, Technology / 14.11.2017

MedicalResearch.com Interview with: Abdul Wase MD FACC FACP FHRS Clinical Professor of Medicine & Director, Cardiology Fellowship Program, Wright State University Boonshoft School of Medicine, Director, Electrophysiology Laboratories Good Samaritan Hospital, Dayton, OH MedicalResearch.com: What is the background for this study? What are the main findings? Response: Implantable cardiac defibrillators (ICD) patients are subject to electromagnetic interferences (EMI) from outside electrical sources. TESLA electric vehicle has a large battery underneath the surface of vehicles, which may potentially interfere with the functioning of these devices. In the owner’s manual, TESLA warns that using mobile connector may impair the functioning of implantable pacemaker or a defibrillator. (more…)
Author Interviews, Breast Cancer, Brigham & Women's - Harvard, Cancer Research, Mammograms, Technology / 20.10.2017

MedicalResearch.com Interview with: Manisha Bahl, MD, MPH Director, Breast Imaging Fellowship Program, Massachusetts General Hospital Assistant Professor of Radiology, Harvard Medical School MedicalResearch.com: What is the background for this study? What are the main findings? Response: Image-guided biopsies that we perform based on suspicious findings on mammography can yield one of three pathology results: cancer, high-risk, or benign. Most high-risk breast lesions are noncancerous, but surgical excision is typically recommended because some high-risk lesions can be upgraded to cancer at surgery. Currently, there are no imaging or other features that reliably allow us to distinguish between high-risk lesions that warrant surgery from those that can be safely followed, which has led to unnecessary surgery of high-risk lesions that are not associated with cancer. We decided to apply machine learning algorithms to help us with this challenging clinical scenario: to distinguish between high-risk lesions that warrant surgery from those that can be safely followed. Machine learning allows us to incorporate the full spectrum of diverse and complex data that we have available, such as patient risk factors and imaging features, in order to predict which high-risk lesions are likely to be upgraded to cancer and, ultimately, to help our patients make more informed decisions about surgery versus surveillance. We developed the machine learning model with almost 700 high-risk lesions, then tested it with more than 300 high-risk lesions. Instead of surgical excision of all high-risk lesions, if those categorized with the model to be at low risk for upgrade were surveilled and the remainder were excised, then 97.4% malignancies would have been diagnosed at surgery, and 30.6% of surgeries of benign lesions could have been avoided. (more…)
Author Interviews, Technology / 19.10.2017

MedicalResearch.com Interview with: Dr. Wenyao Xu, PhD Assistant Professor Department of Computer Science & Engineering University at Buffalo, the State University of New York (SUNY)  MedicalResearch.com: What is the background for this study? What are the main findings? Response: We try to resolve the challenge of Logging-in and logging-out tedious routine. We find it is possible to remotely "listen" to the heartbeat and recognize the user's identity by using a novel doppler radar sensor. (more…)
Anesthesiology, Author Interviews, Pediatrics, Surgical Research, Technology / 18.10.2017

MedicalResearch.com Interview with: Dr. Sunghee Han Professor Seoul National Unversity College of Medicine Seoul National University Hospital Department of Anesthesia and Pain Medicin What is the background for this new technology and study? What are the main findings? Response: The time from patient arrival in the operating theatre to induction of general anesthesia is one of the most stressful moments for children undergoing surgery. Various strategies such as 'pre-operative guided operating room tour' or 'therapeutic play intervention' have been developed in order to reduce children's pre-operative anxiety. Although these existing simulation-based approaches may be effective, they have not been widely used in real clinical settings with limited budget and resources such as manpower and space. Virtual Reality(VR), a relatively new technology in the field of healthcare, can allow the user to experience an immersive environment. In this study, using VR technology, we provided the children with a realistic trip to the operating theatre accompanied by ‘My best friend’ Pororo. “Pororo, The Little Penguin” is a very famous cartoon character in Korea and Asia. Most children in Korea watch Pororo in TV, play with Pororo toys since early yeas and perceive Pororo as a ‘close friend’. In the VR content used in this study, Pororo acts as a patient and is subjected to anesthesia and surgery himself. Pororo kindly brings his friend(the viewer; paediatric patient) to the theatre and shows all that is going on in there. Intervention with the VR content was able to reduce the level of anxiety in paediatric patients and promote collaborative behavior and acceptance of the invasive procedures, especially general anesthesia. Parental satisfaction level was also relatively higher in the VR group. (more…)
Author Interviews, PTSD, Technology / 17.10.2017

MedicalResearch.com Interview with: Dr. Gale Lucas, PhD Director of Research USC Institute for Creative Technologies Playa Vista, CA   MedicalResearch.com: What is the background for this study? What are the main findings? Response: A common barrier to healthcare for psychiatric conditions is the stigma associated with these disorders. Perceived stigma prevents many from reporting their symptoms. Stigma is a particularly pervasive problem among military service members, preventing them from reporting symptoms of combat-related conditions like posttraumatic stress disorder (PTSD). This put them at risk for having their symptoms go untreated, with possible disastrous outcomes including suicide attempts. We envisioned a technology system – a virtual human interviewer – whereby military service members can get feedback about their risk for PTSD in a safe place without stigma. Indeed, our prior research has shown that, because its “just a computer” (therefore safe and anonymous), this virtual human interviewer helps people to feel safe discussing sensitive issues like mental health symptoms. In this follow-up research project (published in Frontiers), we sought to demonstrate the value of this kind of virtual human interviewer specifically for encouraging reporting of PTSD symptoms among service members. Specifically, we were interested in comparing the willingness of service members to report symptoms of PTSD to our virtual human interviewer, compared to the gold standard of the Post Deployment Health Assessment (PDHA). We wanted to isolate the effect of anonymity, separating it from “relational factors” that the virtual human interviewer uses to encourage service members to open up. Indeed, before asking these same questions as on the PDHA to capture PTSD symptoms, the system engages in social dialogue, which build rapport with users. The system asks “get to know you questions,” and throughout the interview, engage in active listening with responses such as nods, smiles, saying “uh huh,” and other encouraging phrases like “that’s great.” (more…)
Asthma, Author Interviews, Technology / 16.10.2017

MedicalResearch.com Interview with: Frank Trudo, MD, MBA Brand Medical Lead US Respiratory AstraZeneca MedicalResearch.com: Would you tell us about Lungprint?  How will Lungprint help asthma patients take better control of their disease? Response: Lungprint is an interactive digital tool that creates a dynamic visual representation of a person’s lungs based on their unique experiences with asthma. It is meant to provide people with asthma a better understanding of the role of asthma in their life and motivate them to have a more personalized conversation with their healthcare provider about the severity of their symptoms, a more individualized treatment plan and a blood test that measures eosinophil levels. Each person’s Lungprint, which is generated as they respond to a digital questionnaire about their experience with asthma, will help reveal information about their individual experience with asthma. You can visit www.lungprint.com to learn more about the tool and create your own Lungprint.  (more…)
Author Interviews, Brigham & Women's - Harvard, Heart Disease, Technology / 20.09.2017

MedicalResearch.com Interview with: Muthiah Vaduganathan, MD, MPH Brigham and Women’s Hospital Heart & Vascular Center and Harvard Medical School Boston, Massachusetts MedicalResearch.com: What is the background for this study? What are the main findings? Response: The CardioMEMS™ HF System (Abbott, Sylmar, CA) is a commercially-available, wireless hemodynamic monitor that can be permanently implanted in the pulmonary artery (PA) to permit real-time, remote monitoring of PA pressures to enhance clinical decision-making in patients with heart failure (HF). Based on a favorable safety profile and the results of the CHAMPION trial, the US Food and Drug Administration (FDA) approved the device in May 2014. Since FDA approval, the device is being implanted in older patients with greater comorbidities compared with those enrolled in CHAMPION. Limited safety data are available after market introduction in this higher-risk pool. (more…)
Author Interviews, Emergency Care, Infections, Pediatrics, Technology / 19.09.2017

MedicalResearch.com Interview with: Prof. Alain Gervaix Head of the Emergency Division Department of Children and Adolescents University Hospitals of Geneva Switzerland MedicalResearch.com: What is the background for this study? Response: Many are familiar with the following ‘seemingly’ simple clinical dilemma that occurs on a daily basis across the world. A patient visits the doctor with a fever. Commonly, assigning a diagnosis comes down to deciding whether the infection is bacterial or viral. Accordingly, the doctor decides if to treat or not to treat with antibiotics. The problem is that bacterial and viral infections often present with very similar symptoms, causing uncertainty that leads to antibiotics being used, in many instances, when they are not needed. This antibiotic misuse contributes to the rise of antimicrobial resistance, one of the biggest health threats of the 21st century. Host biomarkers hold great promise as routine diagnostic tools that can assist doctors in making correct antibiotic treatment decisions, as they overcome key limitations of currently applied pathogen-based tests. Recently, a novel host-assay (ImmunoXpert™) for differentiating bacterial from viral infections was developed and validated to yield high sensitivity and specificity. The three-protein host-assay comprises tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), Interferon gamma-induced protein-10 (IP-10) and C-reactive protein (CRP). (more…)
Annals Internal Medicine, Author Interviews, Flu - Influenza, Merck, Technology / 11.09.2017

MedicalResearch.com Interview with: Jesse Papenburg, MD MSc FRCPC FRQS Clinical Research Scholar Assistant Professor of Pediatrics, McGill University Div. of Pediatric Infectious Diseases, Dept. of Microbiology Montreal Children’s Hospital Montreal, QC  MedicalResearch.com: What is the background for this study? What are the main findings? Response: Influenza viruses cause yearly epidemics of acute respiratory illness affecting 5 to 30 percent of the population. Diagnosing influenza on the basis of only clinical symptoms is difficult because its manifestations vary and are nonspecific. Reverse transcriptase polymerase chain reaction (RT-PCR) is the gold standard for flu diagnosis, but these tests must be sent to a laboratory and have turnaround times that extend beyond the clinical encounter. Rapid and accurate diagnosis of influenza has the potential to improve patient outcomes and decrease health care costs. Since 2011, two novel classes of rapid influenza diagnostic assays i.e., with results available in <30 minutes, have been commercialized with claims of improved sensitivities based on technological improvements: 1) automated immunochromatographic antigen detection tests (digital immunoassays, DIAs) and 2) rapid nucleic acid amplification tests (NAATs). Our systematic review and meta-analysis synthesized the available evidence and compared the diagnostic accuracy of commercially available rapid tests for the detection of influenza A and B infection:
  • Overall, the rapid tests displayed very high specificities (≥98%). Physicians can therefore diagnose influenza with confidence on the basis of a positive RIDT, DIA, or rapid NAAT result.
  • The pooled sensitivities for DIAs (80.0% for influenza A and 76.8% for influenza B) and rapid NAATs (91.6% for influenza A and 95.4% for influenza B) are markedly higher than those for RIDTs (54.4% for influenza A and 53.2% for influenza B).
(more…)
Allergies, Author Interviews, Brigham & Women's - Harvard, Pediatrics, Technology / 07.09.2017

MedicalResearch.com Interview with: Lee, Hakho, PhD Department of Systems Biology Harvard Medical School Boston, Massachusetts MedicalResearch.com: What is the background for this study? What are the main findings? Response: The incidence of food allergy is increasing worldwide, particularly among children, and yet no handy test is available for general public. There are plenty of allergens testing methods for the factories producing the products, we wanted to solve this issue. Our pilot test showed wide variation in allergen contents in packaged food products and restaurant meals. Hidden allergens (like gluten in salad dressing, likely from additives) were also found. (more…)
Author Interviews, Stem Cells, Technology / 25.08.2017

MedicalResearch.com Interview with: John Arnone Chairman and CEO American CryoStem Corporation MedicalResearch.com: What is the background for this your company American CryoStem? Response: American CryoStem Corporation (CRYO) was founded in 2008, to allow individuals, researchers and physicians to collect-process-store stem cells derived from adipose tissue (fat) to prepare for their current or future use. Over the years the Company has become a biotechnology pioneer, standardizing adipose tissue derived technologies (Adult Stem Cells) for the fields of Regenerative and Personalized Medicine. The Company operates a state-of-art, FDA-registered, clinical laboratory in New Jersey and licensed laboratories in Hong Kong, China and Tokyo, Japan, which operate on our proprietary platform, dedicated to the collection, processing, bio-banking, culturing and differentiation of adipose tissue (fat) and adipose derived stem cells (ADSCs) CRYO maintains a strategic portfolio of intellectual property, 18 patents that surround the Companies proprietary technology which supports a growing pipeline of stem cell applications and biologic products. We are leveraging our proprietary platform and our developed product portfolio to create a domestic and global footprint of licensed laboratory affiliates, physicians networks and research organizations who purchase tissue collection, processing and storage services and consumables from the Company. CRYO’s laboratory stem cell bank/line products are characterized adult human Mesenchymal Stem Cell (MSC's) derived from adipose tissue that work in conjunction with our 13 patented (non-animal) medium lines. The Company's R&D efforts are focused on university and private collaborations to discover, develop and commercialize ADSC therapies by utilizing our standardized collection-processing-storage methodology and laboratory products combined with synergistic technologies to create jointly developed regenerative medicine applications and intellectual property. (more…)
Blood Pressure - Hypertension, Columbia, Technology / 21.08.2017

MedicalResearch.com Interview with: Gregg W. Stone MD Professor of Medicine Columbia University Director of Cardiovascular Research and Education Center for Interventional Vascular Therapy New York Presbyterian Hospital/ Columbia University Medical Center Co-Director of Medical Research and Education The Cardiovascular Research Foundation New York, NY MedicalResearch.com: How does the MobiusHD system work? Response: The MobiusHD System is a thin stent-like device which is implanted during a minimally invasive procedure into the carotid artery. The MobiusHD modifies the activity of baroreceptors located in the carotid artery, increasing arterial vasodilation to reduce blood pressure. (more…)
Author Interviews, Technology / 18.08.2017

MedicalResearch.com Interview with: Ken Long, MD/PhD student Department of Bioengineering Micro and Nano Technology Laboratory University of Illinois at Urbana-Champaign Urbana, Illinois MedicalResearch.com: What is the background for this study? What are the main findings? Response: Traditional laboratory-based spectrometers are a mainstay of clinical diagnostics.  In our recent Lab on a Chip article we sought to produce a handheld device that would be able to perform three broad classes of spectrometric tests that one might normally do in a laboratory (Transmission-based, Reflection-based, and Intensity-based) on a smartphone-based handheld device that could be used at the point-of-care. Using high-resolution 3D printing, a custom optical fiber, and some off-the-shelf lenses, we were able to design, assemble, and demonstrate a device capable of reproducing results of traditional benchtop equipment when measuring results from commercially-available tests.  The device is small enough to hold in the palm of your hand, cost less than $550 to build the prototype, and has the ability to read multiple tests using the video-capture capabilities of the smartphone and a swiping motion with liquid test cartridges, much like swiping a credit card through a reader.  The two tests demonstrated in the paper were for a biomarker associated with pre-term birth in pregnant women, and a PKU test for newborns that can defect a critical nutritional enzyme deficiency. (more…)
Author Interviews, Psychological Science, Technology / 07.08.2017

MedicalResearch.com Interview with: Mag. Nicole Mirnig  Research Fellow Center for Human-Computer Interaction University of Salzburg Salzburg, Austria  MedicalResearch.com: What is the background for this study? What are the main findings? Response: From our previous research on social robots, we know that humans show observable reactions when a robot makes an error. These findings result from a video analysis we performed over a large data corpus from different human-robot interaction studies. With the study at hand, we wanted to replicate this effect in the lab in order to explore into more detail how humans react and what they think about a robot that makes a mistake. Our main findings made us quite excited. First of all, we could show that humans respond to faulty robot behavior with social signals. Second, we found that the error-prone robot was perceived as significantly more likeable than the flawless robot. One possible explanation for this finding would be the following. Research has shown that people form their opinions and expectations about robots to a substantial proportion on what they learn from the media. Those media entail movies in which robots are often portrayed as perfectly functioning entities (good or evil). Upon interacting with a social robot themselves, people adjust their opinions and expectations based on their interaction experience. We assume that interacting with a robot that makes mistakes, makes us feel closer and less inferior to technology. (more…)
Author Interviews, Stroke, Technology / 01.08.2017

MedicalResearch.com Interview with: Bertrand LAPERGUE, MD, PhD Hôpital Foch, University Versailles Saint Quentin en Yvelynes Department of Stroke Center, Diagnostic and Interventional Neuroradiology Suresnes, France. Michel PIOTIN, MD Department of Diagnostic and Interventional Neuroradiology Fondation Rothschild, Paris, France. on behalf of the ASTER Trial Investigators. MedicalResearch.com: What is the background for this study? What are the main findings? Response: Mechanical thrombectomy (MT) with a stent retriever (SR), in association with intravenous (IV) rtPA, is now the standard of care in anterior circulation ischemic stroke caused by large vessel occlusion (LVO). Favorable outcome is strongly associated with the successful reperfusion status (TICI 2b/3= 71% with SR, Hermes Study group). New techniques for MT such as ADAPT (A Direct first pass Aspiration Technique) seem promising to increase reperfusion status and clinical outcome in retrospective studies. (more…)
Author Interviews, Hearing Loss, Technology / 20.07.2017

MedicalResearch.com Interview Provided on behalf of: Jan Janssen, Senior Vice President Research and Development Cochlear LimitedJan Janssen, Senior Vice President Research and Development Cochlear Limited MedicalResearch.com: What is the background for this device? Response: Cochlear implants treat hearing loss by electrical stimulation of the hearing nerve, bypassing the damaged parts of the hearing pathway. Cochlear implants system consist out of an external sound processor that detects and processes the sounds and then sends them to the implant. The implant receives this information and turns it into electrical signals that are delivered to the hearing nerve and from there to the brain. The Nucleus® 7 Sound Processor is the world’s first and only Made for iPhone cochlear implant sound processor, allowing users to stream sound from their iPhone®, iPad® and iPod touch® directly to their cochlear implant sound processor. It not only enhances the experience of talking on the phone, it also makes features like enjoying music or watching videos, as well as audio apps such as Maps or FaceTime, more easily accessible. The Nucleus 7 Sound Processor is also the smallest and lightest behind-the-ear sound processor on the market. (more…)
Alzheimer's - Dementia, Author Interviews, Cognitive Issues, Technology / 18.07.2017

MedicalResearch.com Interview with: Douglas W. Scharre MD Professor of Clinical Neurology and Psychiatry Director, Division of Cognitive Neurology Department of Neurology Director, Center for Cognitive and Memory Disorders Director, Memory Disorders Research Center Co-Director, Neuroscience Research Institute Ohio State University Wexner Medical Center Columbus, OH   MedicalResearch.com: What is the background for this study? What are the main findings? Response: Self-Administered Gerocognitive Examination (SAGE) is a pen-and paper, valid and reliable cognitive assessment tool for identifying individuals with mild cognitive impairment (MCI) or early dementia. We published age and education normative data on SAGE and determined that one point be added to the scores when age over 79 and one point be added when education level is 12 years or less. We evaluated the identical test questions in digital format (eSAGE) made for tablet use, adjusted with previously published age and education norms, and determined eSAGE’s association with gold standard clinical assessments. eSAGE is commercially known as BrainTest. (more…)
Author Interviews, Technology / 14.07.2017

MedicalResearch.com Interview with: Dr Ian Williams PhD Associate Professor, DMT Lab Birmingham City University Faculty of Computing, Engineering and the Built Environment Centre for Digital Media Technology Millennium Point Birmingham UK MedicalResearch.com: What is the background for your work? Response: Our work at the DMT Lab (dmtlab.bcu.ac.uk) focuses on developing a novel Mixed Reality (MR) medical presentation platform which allows practitioners to interact with patient data and virtual anatomical models in real time. The system enables the presentation of medical data, models and procedures to patients with the aim of educating them on pending procedures or the effects of lifestyle choices (for example the effects of smoking or excessive alcohol consumption). The system employs an exocentric mixed reality environment which can be deployed in any room. It integrates a medical practitioner in real time with multimodal patient data and the corresponding result is a real time co-located visualisation of both the practitioner and the data, which they can interact with in real time.  We implement a natural interaction method into the system which improves a user’s level of direct interaction with the virtual models and provides a more realistic control of the data. The system can also be used in a fun educational setting where patients, students, children or any naive user, can learn about medical anatomical information via a real-time interactive mixed reality “body scanner”. This fun system overlays the MR information onto their own body in real-time and shows them scaled and interactive virtual organs, anatomy and corresponding medical information. We are aiming for this system to be used not only in patient education but also in engaging and informing people on lifestyle choices. (more…)
Author Interviews, Diabetes, Technology / 13.07.2017

MedicalResearch.com Interview with: David Moore MBA Senior Vice President of Marketing Novo Nordisk  MedicalResearch.com: What is the Cornerstones4Care Powered by Glooko (C4C) App? Response: The Cornerstones4Care® Powered by Glooko® App marries Novo Nordisk’s extensive knowledge of diabetes and personalized patient support with Glooko’s digital platform and data analytics expertise. The App is comprehensive tool that helps patients track meals, activity, medicine and blood sugar – in one convenient place – and is intended to help people learn how to better manage diabetes through their mobile devices. MedicalResearch.com: What functions will people with diabetes have access to? How can the app help people living with diabetes control their disease?    Response: The Cornerstones4Care® Powered by Glooko® App marries Novo Nordisk’s extensive knowledge of diabetes and personalized patient support with Glooko’s digital platform and data analytics expertise. The App is comprehensive tool that helps patients track meals, activity, medicine and blood sugar – in one convenient place – and is intended to help people learn how to better manage diabetes through their mobile devices. (more…)
Author Interviews, Exercise - Fitness, Technology / 10.07.2017

MedicalResearch.com Interview with: Jacob Barkley, Ph.D., College of Education, Health and Human Services Kent State  MedicalResearch.com: What is the background for this study? Response: Our group has demonstrated that cellular telephone (cell phone) use is positively associated with sedentary behavior (i.e., sitting). To that end, high cell phone users sit for 80 to 100 minutes longer than their lower-use peers. We have also shown that cell phone use during exercise decreases exercise intensity and slows free-living walking speed. In other words, cell use may be comparable to traditional sedentary screen use in that it promotes sitting and may interfere with physical activity. However, some cell phone functions may actually promote positive health behaviors. Fitness apps, connecting with active peers and administering health recommendations via the cell phone all may have utility in promoting physical activity and reducing sedentary behavior. While not well studied, novel physically-interactive cell phone games may also promote physical activity. One such game, Pokémon Go! requires users to walk through real environments and locate avatars in the game using GPS. The purpose of the game is to find these avatars. In order to find more avatars, the player will need to walk to more areas. Therefore, playing Pokémon Go! may promote walking. (more…)
Author Interviews, Social Issues, Technology / 07.07.2017

MedicalResearch.com Interview with: Leon Sütfeld The Institute of Cognitive Science University of Osnabrück  MedicalResearch.com: What is the background for this study? What are the main findings? Response: Self-driving cars, and especially future fully autonomous cars, pose a number of ethical challenges. One of these challenges is making the "right" decision when it comes to a so-called dilemma situation, in which a collision is unavoidable (or highly probable), but a decision can be made as to which of multiple different collisions to choose. Our study assesses the behavior of human participants in such dilemma situations and evaluates algorithmic models that are trained on this data to make predictions. Our main findings are that in a controlled virtual reality environment, the decisions of humans are fairly consistent and can be well described by simple value-of-life models. (more…)
Author Interviews, Neurological Disorders, Technology / 29.06.2017

MedicalResearch.com Interview with: Howard Jay Chizeck ScD Professor, Electrical Engineering Adjunct Professor, Bioengineering Co-Director UW Biorobotics Laboratory Graduate Program in Neuroscience UW CoMotion Presidential Innovation Fellow Research Thrust Testbed Co-Leader MedicalResearch.com: What is the background for this study? What are the main findings? Response: Essential Tremor is treated using Deep Brain Stimulation (DBS) in some patients. Current clinical practice involves Deep Brain Stimulation with an "always on" stimulation. This causes extra battery drain, because stimulation is applied when not needed. Also excessive stimulation is not necessarily a good thing, Our work is aimed at adjusting the stimulation, so that it comes on and turns off only when needed to suppress tremor symptoms. (more…)
Author Interviews, Emory, Flu - Influenza, Lancet, Technology, Vaccine Studies / 28.06.2017

MedicalResearch.com Interview with: Dr Nadine G Rouphael MD Associate Professor of Medicine, Emory University Director of the VTEU and HIPC networks at the Hope Clinic of the Emory Vaccine Center Decatur GA 30030, USA MedicalResearch.com: What is the background for this new technology and study? What are the main findings? Response: Different groups including a group of researchers at Georgia Tech have been working on the microneedle technology for more than 20 years. The dissolvable microneedle patches are already used in several cosmetic products and drugs. However, vaccination with microneedle patches has been studied mostly in animals. Our phase 1 trial published this week in The Lancet showed that vaccination with the microneedle patches was safe, with no related serious adverse events reported. Local skin reactions to the patches were mostly mild itching and faint redness that lasted two to three days. No new chronic medical illnesses or influenza-like illnesses were reported with either the patch or the injection groups. Antibody responses generated by the vaccine, as measured through analysis of blood samples, were similar in the groups vaccinated using patches and those receiving intramuscular injection, and these immune responses were still present after six months. When asked after immunization, more than 70 percent of patch recipients reported they would prefer patch vaccination over injection or intranasal vaccination for future vaccinations. (more…)
Addiction, Author Interviews, Technology / 24.06.2017

MedicalResearch.com Interview with: Dr. Phil Reed,  D.Phil. Professor Psychology Swansea University MedicalResearch.com: What is the background for this study? What are the main findings? Response: Problematic internet use has been a growing concern for many people and bodies over the last decade, and more study has been requested into various aspects of this possible disorder.  One of the key questions is whether people overuse the internet, due to an addiction.  If it is an addiction, then there should be signs of withdrawal when people, who report having this problem, stop using the internet.  In this study, 144 participants, aged 18 to 33, had their heart rate and blood pressure measured before and after a brief internet session.  Their anxiety and self-reported internet addiction were also assessed. The results showed increases in heart rate and systolic blood pressure on terminating the internet session for those with problematically-high internet usage.  These increases in physiological arousal were mirrored by increased feelings of anxiety.  However, there were no such changes for those participants who reported no internet-usage problems. (more…)
Author Interviews, Dental Research, Technology / 14.06.2017

MedicalResearch.com Interview with: Avathamsa Athirasala, MSE and Luiz E. Bertassoni, DDS PhD Biomaterials and Biomechanics, School of Dentistry Center for Regenerative Medicine, School of Medicine Biomedical Engineering, School of Medicine Portland OR 97201 USA MedicalResearch.com: What is the background for this study? What are the main findings? Response: Current clinical practices for root canal treatment involve replacing the damaged tissue with inert, synthetic materials. While these procedures are able to arrest infection and decay in the tooth, they do not restore its biological function causing it to become weaker and more prone to fractures. We are focused on the regeneration of pulp tissue instead and in this study, we have developed a strategy to apply tissue-engineering concepts to engineer dental pulp-like tissue constructs, complete with blood vessels, which can, in principle, integrate with existing vasculature when introduced at the site of injury and form healthy pulp tissue. (more…)
Author Interviews, Heart Disease, Karolinski Institute, Technology / 14.06.2017

MedicalResearch.com Interview with: “drones” by Andrew Turner is licensed under CC BY 2.0Andreas Claesson, RN, Paramedic PhD Centre for resuscitation science Karolinska institute Stockholm, Sweden. MedicalResearch.com: What is the background for this study? What are the main findings? Response: Survival from out-of-hospital cardiac arrest is low, the technology is existing. When implementing this kind of system with a drone equipped with an AED, defibrillation may occur at an early stage and before EMS arrival mainly in rural areas. (more…)
Author Interviews, Education, Psychological Science, Technology, University of Pennsylvania / 21.05.2017

MedicalResearch.com Interview with: Jason Han, MD Resident, Cardiothoracic Surgery Hospital at the University of Pennsylvania MedicalResearch.com: What is the background for this study? What are the main findings? Response: The inspiration for this study comes from my personal experience as a medical student on clinical rotations. Despite having been a victim of a medical error while growing up myself, I found it extraordinarily difficult to admit to even some of my smallest errors to my patients and team. Perplexed by the psychological barriers that impeded error disclosure, I began to discuss this subject with my advisory Dean and mentor, Dr. Neha Vapiwala. We wanted to analyze the topic more robustly through an academic lens and researched cognitive biases that must be overcome in order to facilitate effective disclosure of error, and began to think about potential ways to implement these strategies into the medical school curriculum with the help of the director of the Standardized Patient program at the Perelman School of Medicine, Denise LaMarra. We ultimately contend that any educational strategy that aims to truly address and improve error disclosure must target the cognitive roots of this paradigm. And at this point in time, simulation-based learning seems to be the most direct way to do so, but also remain hopeful that emerging technologies such as virtual and augmented reality may offer ways for students as well as staff to rehearse difficult patient encounters and improve. (more…)