MedicalResearch.com - Latest news, interviews, and insights into medical research, health and wellness, fitness and addiction.
Author Interviews, Pain Research, Pharmacology / 09.06.2025

MedicalResearch.com Interview with: Prof. Alexander Binshtok PhD Cecile and Seymour Alpert Professor in Pain Research Hebrew University’s Faculty of Medicine and Center for Brain Sciences (ELSC) MedicalResearch.com: What is the background for this study? Response: Paracetamol (also known as acetaminophen) is one of the world’s most commonly used pain relievers and fever reducers, yet for decades, its precise biological mechanism has remained something of a mystery. Traditionally, scientists believed its analgesic effect stemmed from central nervous system activity—specifically through the action of its metabolite, AM404, on cannabinoid and TRPV1 receptors in the brain. (more…)
Pharmacology / 03.05.2025

Biostatistics serves as the backbone of clinical research, converting raw data into meaningful insights that inform medical decision-making. Its methods guide every phase of a study—from how it's designed to how the results are evaluated—ensuring that findings are not only accurate but also relevant to real-world healthcare. As noted by Busuyi Agbetunsin, this scientific field contributes to the credibility of clinical trials, supports regulatory approvals, and strengthens the foundation of evidence-based medicine. Its influence stretches across drug development, disease prevention, and health policy, making it a crucial tool in the advancement of modern medicine. (more…)
Pharmaceutical Companies, Pharmacology / 02.05.2025

Effective Medicine Distribution Center   Running a medicine distribution center isn’t just about moving boxes from point A to point B. You’re dealing with products that save lives, so there’s no room for guesswork.  Every pill, vial, and package needs to be handled with care, tracked precisely, and delivered fast. You’ve got to think like a health worker, a warehouse manager, and a logistics expert—all at once.  If you mess up, people don’t get the meds they need. But when you do it right, you become a silent hero in the healthcare chain.  In this article, you’ll find smart, practical ways to run a distribution center that actually works—keeping meds safe, fresh, and on time, every time. 
  1. Optimize Your Inventory Management
You can’t run a smooth medicine center if you don’t know what’s on your shelves. Imagine getting an urgent order for insulin—only to realize you ran out last week. That’s a nightmare.  To avoid chaos, you need a smart inventory system that tracks every item in real time. Barcode scanners, digital dashboards, and simple forecasting tools can save your day—and your reputation. Set alerts for low stock, expiration dates, and fast-moving items.  Don’t let medicine collect dust or go to waste. Rotate stock regularly (first in, first out), and make room for incoming deliveries by keeping your shelves organized. If it feels like a game of Tetris, you’re doing it right.  The more you stay ahead of the numbers, the fewer emergencies you’ll face. And that means faster service, fewer headaches, and a smoother operation all around. Keep things tight, and your center will run like clockwork. (more…)
Compliance, Pharmacology / 04.04.2025

Keeping patients on track with their medication during clinical trials is extremely important. If they don’t follow the plan, it can throw off results, slow down new treatments, and even put their health at risk. Healthcare providers must be proactive with medication adherence solutions to make sure patients take their meds as prescribed, keeping trials on schedule and producing reliable data.

Understanding the Importance of Medication Adherence in Patient Care

Medication adherence is all about whether patients take their meds as they should. If they stick to the schedule, treatments work better, healthcare costs decrease, and trial data stays accurate. Keeping patients on track is essential for providers to protect trial results and patient well-being. Using medication adherence solutions for healthcare providers helps improve accuracy, build patient trust, and keep trials running smoothly. When patients feel supported, they’re more likely to follow their treatment plan. Clinical trials need precise data to figure out if a treatment actually works. Researchers can't get clear answers if patients skip doses or take the wrong amount. That’s why improving adherence isn’t just a good idea—it’s essential for medical progress. (more…)
Pharmacology / 04.04.2025

In the pharmaceutical industry, precision isn’t just a preference—it’s a necessity. The margin for error in storing temperature-sensitive products such as vaccines, biologics, and critical medications is razor-thin. Even a slight temperature deviation can compromise product integrity, leading to significant financial losses and jeopardizing patient safety. As the global demand for reliable cold storage grows, advanced solutions are becoming more than just beneficial—they’re essential. This is where cutting-edge ultra-low temperature storage systems come into play, offering unmatched control, safety, and efficiency. Today’s pharmaceutical companies need storage that not only meets but exceeds regulatory expectations, all while supporting operational scalability and sustainability goals. (more…)
Mental Health Research, Pharmacology / 29.03.2025

Psychological research plays a fundamental role in shaping advancements in mental health care and pharmaceutical developments. By studying cognitive and behavioral patterns, researchers uncover crucial insights that drive the creation of effective treatments. Theodore Rex Walrond notes how these findings inform the development of medications that target neurotransmitter imbalances, improving outcomes for individuals with conditions like depression and anxiety.

(more…)
Pharmaceutical Companies, Pharmacology / 14.02.2025

Although each rare disease is uncommon on its own, together, they represent a major global health challenge. With over 7,000 known rare diseases, the global impact is substantial. Currently, around 300 million people worldwide are living with a rare disease.  Unlike more prevalent conditions, rare diseases often receive less research funding, making drug development a lengthy and challenging process. However, recent advancements in antibody drug discovery are transforming this landscape, offering new hope to millions of patients. Antibody drug discovery is an advanced biotechnology field that utilizes the immune system to develop precise treatments. Scientists identify and isolate specific antibodies capable of binding to disease-causing targets. This approach enables the creation of drugs that directly address the root cause of rare diseases, ensuring more effective and personalized therapies. In this article, we will explore the transformative impact of antibody drug discovery on rare disease research. 

Precision Targeting for Effective Treatment

A key advantage of antibody-based therapies is their ability to achieve precision targeting, which is essential for treating rare diseases. Since many rare diseases stem from genetic mutations or protein dysregulation, they are well-suited for highly specific and targeted interventions.  Antibodies can be designed to target disease-causing molecules like misfolded proteins, overactive receptors, or harmful cells while preserving healthy tissues. This precision improves treatment effectiveness and minimizes side effects, which is essential for patients with complex or fragile health conditions. To harness this potential, researchers are increasingly relying on advanced antibody discovery services. These services employ advanced technologies like phage display, single B-cell screening, and AI modeling to identify and refine high-affinity, specific antibodies for rare diseases. Partnering with specialized antibody discovery services helps researchers fast-track tailored therapies, offering hope to patients with untreatable conditions. This collaborative approach is revolutionizing rare disease research, leading to innovative treatments that target the root causes of complex disorders. Alloy Therapeutics recommends collaborating with an expert team to develop ranked bispecific candidates tailored to specific targets. Their comprehensive approach combines advanced technologies with proprietary workflows. This ensures the delivery of precise, high-quality bispecific leads for effective therapeutic development. (more…)
Pharmacology / 11.02.2025

In today's healthcare landscape, personalized treatment is becoming increasingly essential. Patients have unique medical needs that off-the-shelf medications often fail to address. This is where compounding services offer customized pharmaceutical solutions tailored to an individual’s specific requirements. Unlike mass-produced medications, compounded drugs are formulated by specialized pharmacists who create precise dosages, unique formulations, and alternative delivery methods to enhance treatment effectiveness. As the demand for patient-centric care grows, compounded medications are emerging as the future of modern healthcare.   Understanding Compounding Services Compounding is a pharmaceutical practice allowing licensed pharmacists to modify, mix, or create medications to suit a patient's needs. Unlike traditional pharmacy prescriptions, which rely on standard formulations, compounded medications offer flexibility in dosage, ingredients, and delivery methods. This approach ensures that individuals receive treatments specifically designed for their medical conditions, allergies, and preferences. (more…)
Pharmacology / 02.02.2025

SkyCell has emerged as a transformative force in pharmaceutical logistics, offering innovative solutions that ensure the safe, secure, and sustainable transportation of temperature-sensitive medicines. It’s not surprising that the company is an industry leader having introduced hybrid containers to the world. Should you work with them?  Find it out in this article

SkyCell's Innovative Hybrid Containers

At the core of SkyCell's offerings are its temperature-controlled hybrid containers, designed to provide superior protection for sensitive pharmaceuticals during transit. These containers feature a patented insulation system that reflects heat radiation, maintaining a consistent internal temperature without the need for external power sources. The 1500X model, for instance, offers enhanced performance with a longer independent run-timeof up to 270 hours, ensuring stability even in extreme ambient temperatures ranging from +70°C to -40°C. (more…)
Addiction, addiction-treatment, Pharmacology / 28.01.2025

Drug detoxification is a critical first step in the recovery journey for those struggling with substance use disorders. Whether it's alcohol, opioids, stimulants, or other drugs, the detox process involves the body's effort to remove toxic substances accumulated from drug use. But what exactly happens in the body during detox? What physiological and psychological changes take place? All of these questions are answered by experts at Oasis Detox. Understanding this process is key to realizing why detox is such a crucial phase in overcoming addiction. 

What is Drug Detoxification?

Drug detoxification, or detox, is the process by which the body eliminates the harmful substances accumulated through drug use. Detoxification isn't just about stopping drug intake; it's the natural, biochemical process that the body undergoes to clear these substances from the bloodstream and tissues, restoring balance. While detox can be done at home in some cases, medical supervision is often essential, especially when withdrawing from substances like alcohol, opioids, or benzodiazepines. Withdrawal symptoms can range from mild to life-threatening, depending on the drug, the duration of use, and the individual's health. (more…)
Drug Approval, Pharmacology / 04.12.2024

quality-by-design in biopharmaceutical development The biopharmaceutical industry has undergone significant transformations in recent years, particularly with the adoption of Quality by Design (QbD) principles. This innovative approach is reshaping the landscape of biopharmaceutical manufacturing by fostering a culture of quality that prioritises proactive measures over reactive solutions. This transformation not only enhances the efficiency of manufacturing processes but also ensures that patients receive safe and effective medications.

What is Quality by Design (QbD)?

Quality by Design is a strategic framework introduced to ensure that quality is built into pharmaceutical products from the outset, rather than being tested in at the end of the manufacturing process. This concept emerged from the need for a more scientific and risk-based approach to drug development, particularly in light of the complexities inherent in biopharmaceutical manufacturing. QbD is built upon several core elements, including:
  • Quality Target Product Profile (QTPP): This outlines the desired characteristics of the final product, including its intended use, dosage form, and delivery method.
  • Critical Quality Attributes (CQAs): These are the physical, chemical, and biological properties that must be controlled to ensure the product meets its QTPP.
  • Critical Process Parameters (CPPs): These are the variables that influence the CQAs during manufacturing and must be monitored to maintain product quality.
(more…)
Legal-Malpractice, Pharmacology / 21.11.2024

Running a pharmacy may be both gratifying and difficult. The healthcare sector depends heavily on chemists. Because they provide the prescription medications, advice, and support that patients need to improve their results. But these obligations also carry several serious concerns. The challenges of owning and operating a pharmacy are unique. From the possibility of drug mistakes to the physical risks of the job. This article will discuss several hazards that come with operating a pharmacy. Talk about how crucial pharmacy insurance is to effectively controlling these risks as well.

Most Significant Risks Associated with Running a Pharmacy

Let's review some of the biggest dangers that come with owning a pharmacy and how they might be lessened with pharmacy insurance.

Medication Errors and Liability

Medication errors are one of the most common risks in the pharmacy field. Mistakes in filling prescriptions and incorrect dosages can have serious consequences and provide the wrong medication which also leads to significant harm. Sometimes life-threatening consequences. Human mistakes are unavoidable, and pharmacies may be sued by impacted patients or their families despite having strict protection in place. Pharmacy liability insurance can protect in case of claims made by patients harmed by medication errors. This coverage typically includes legal defence costs and settlements. Also, other expenses are associated with the claim. It helps the pharmacy recover financially and continue operating. (more…)
Author Interviews, Pharmacology / 12.11.2024

medical medicine box You might have noticed the key details mentioned on medical medicine boxes whenever you pick them up from a pharmacy. Information, precautions, symbols, and brand details mentioned on these boxes are important for individuals who are going to consume these medicines. Custom medicine boxes thus serve as an effective means of conveying the desired insights to the exact audience who is going to benefit from the relevant medicines for curing their specific health issues. Brands make sure to keep the details mentioned on medical medicine boxes highly relevant and assure the safety of individuals at all times while keeping them informed of the right dose of the medicine they are going to consume. This post explores how important are these custom packaging solutions for your pharmaceutical brand and what are the key features of medical medicine boxes. (more…)
Author Interviews, Health Care Systems, JAMA, Pharmacology, University of Pittsburgh / 31.10.2024

MedicalResearch.com Interview with: Katie J. Suda, PharmD, M.S., FCCP Professor of medicine with tenure Associate Director, Center for Pharmaceutical Policy and Prescribing University of Pittsburgh School of Medicine MedicalResearch.com: What is the background for this study? Response: Our pharmaceutical supply chain is global where the manufacturing process for one drug may occur in multiple countries. Sometimes there are breakdowns in the pharmaceutical supply chain which may threaten access to medicines. Breakdowns in the supply chain occur for medicines manufactured in the U.S. and by international partners. While breakdowns in the supply chain occur for hundreds of drugs each year, not all result in a decrease in available supply (a “drug shortage”) because of action taken by manufacturers, pharmacies and drug regulators (e.g., the U.S. Food and Drug Administration [FDA]). Drug shortages are a critical concern to public health as pharmacies, clinicians, and patients struggle to identify safe and effective alternatives. In addition, drug shortages have been associated with adverse patient outcomes and medication safety events. Recently, drug shortages have gotten worse with shortages occurring with increasing frequency and lasting longer. There has also been a shift in the types of medicines in shortage from drugs primarily used in hospitals, such as injectables, to oral medicines frequently used to manage outpatient conditions. Countries have different regulatory authority and policy which may impact how drug supply chain breakdowns result in drug shortages. We wanted to know if there are differences between the U.S. and Canada in the frequency that national drug shortages occur after supply chain breakdowns are reported in both countries. Canada is a good comparator to the U.S. because Canada has similar drug regulatory standards and manufacturing inspections. Prescription drug coverage is also similar for the two countries where half of prescriptions are reimbursed through public insurance and half through private insurance and out-of-pocket. (more…)
Cost of Health Care, Diabetes, Pharmacology / 21.10.2024

Access to affordable insulin remains a challenge for millions of people living with diabetes around the world, particularly in middle-income countries. To bridge this gap, platforms are emerging that connect patients with high-quality insulin at reduced prices. For individuals struggling to afford their life-saving medication, these services offer a convenient and affordable solution, making a significant impact on global health.

The Global Insulin Crisis

Diabetes affects millions worldwide, and the demand for insulin continues to rise. Major insulin manufacturers, including Novo Nordisk, Eli Lilly, and Sanofi, dominate the global market, producing essential medications for managing blood sugar levels. However, in many parts of the world, including countries like India, Mexico, and the Philippines, insulin prices remain prohibitively high. This leaves a substantial portion of the population without access to the medication they need to live healthy lives. Data shows that insulin prices are often out of reach for people in middle-income countries. The situation is particularly dire in regions like Kenya, Malaysia, and Vietnam, where the cost of insulin may equal a month's salary. With nearly three major companies controlling the insulin market, competition is limited, and prices remain high. As a result, many patients with type 1 and type 2 diabetes face inconsistent access to insulin, which can put their health at significant risk. (more…)
Pharmacology / 02.10.2024

Editor's note:  Don't delay seeking advice from your health care provider with prolonger over-the-counter remedies. Some conditions, including but limited to persistent cough, gastrointestinal symptoms, headache etc may be a symptom of a more serious condition and should be evaluated by your doctor or provider. Have you ever thought about how convenient it would be if your local pharmacy was just a few clicks away? Well, with the rise of online pharmacies, that's exactly the reality for many people. These digital services have become a practical solution for managing a wide range of health conditions. Whether you need professional advice or simply want the convenience of ordering treatments from the comfort of your own home, an online pharmacy can be a reliable and efficient partner in maintaining your health.

Managing Minor Health Issues with Ease

We all deal with minor health complaints from time to time. Maybe its that cold you caught last week is still lingering. When these everyday issues arise, the last thing you want to do is wait in long queues at a pharmacy. Fortunately, online pharmacies are well-equipped to help with a wide range of over-the-counter products for common ailments. For instance, many offer treatments for sniffles, colds, and flu that can be delivered directly to your door. Pain relief options, decongestants, and throat lozenges can all be found online. Along with medications, you can also access advice about symptom management. Often, pharmacists are available for virtual consultations, offering practical advice on what you might need based on your symptoms. (more…)
Drug Approval, Pharmacology / 20.09.2024

FDA drug testing Ever thought what are the next steps after launching a product? Once a product is launched, there is much more to do about FDA approval, particularly with health and safety products. The FDA acts as a protector and safeguard of products, be they medications or medical devices, allowed to enter the U.S. market.  Here, understanding the FDA approval process will benefit you to help understand the complex world of product approval and set real expectations of your product for the market. Let’s look at the basic structure of FDA approval and its after-process.  (more…)
Pharmacology / 20.09.2024

drug safety Pharmacovigilance is the strict monitoring process in the drug industry to ensure that drugs are safe to administer. It simply ensures that public health is kept away from harmful drugs by keeping a tab on any safety concerns with the drug once it is on the market. This blog explains the fundamental characteristics of pharmacovigilance, its significance, and what process is applied. (more…)
Endocrinology, Pharmacology / 20.09.2024

Editor's note:  Consult with your medical provider beginner any form of potential hormonal regulation therapy.   The discussion below has not been FDA verified or approved and should not be construed as specific medical advice. The field of hormone regulation has evolved significantly, offering new treatments that aim to restore balance and improve overall well-being. MedicalNewsToday states that most people go through natural hormonal fluctuations at various stages of their lives. However, imbalances can emerge when the endocrine glands, which create and release hormones into the circulation, do not operate properly. These glands are distributed throughout the body, and each of them handles different organs and physical activities. As more individuals seek solutions for hormone-related issues like fatigue, weight gain, and mood swings, next-generation hormone regulation treatments are becoming increasingly popular. These innovative therapies, such as hormone pellet therapy, bioidentical hormone replacement therapy (BHRT), and peptide therapy, target specific imbalances to provide personalized solutions. These treatments offer hope for improved health, vitality, and quality of life by addressing the root causes of hormone disruptions. (more…)
Cost of Health Care, Pharmacology / 12.09.2024

When you’re at the pharmacy, it’s normal to feel a bit of confusion about whether you would like to receive generic or brand-name medication when the pharmacy technician asks you the usual question. While health professionals, from pharmacists to doctors, nurses, and students of RN to MSN programs, will understand the differences between the two, it's important that you, as a patient, know them, too. In this article, we will break down the differences between generic and brand-name medications so that you will be more aware when you visit the pharmacy.

(more…)

Pharmacology, Semaglutide / 11.08.2024

Oral Semaglutide has emerged as a significant advancement in the realm of weight loss treatments. As an alternative to traditional injectable options, oral Semaglutide offers convenience and effectiveness. This guide provides an in-depth look at oral Semaglutide, its benefits, how to access it through prescriptions, and explores compounded semaglutide online.

What is Oral Semaglutide?

Oral Semaglutide is an oral form of the medication Semaglutide, which was originally available only as an injection. It is used to manage weight loss and control blood sugar levels in individuals with obesity or type 2 diabetes.
  • Mechanism of Action: Semaglutide mimics a hormone called GLP-1, which helps regulate appetite and insulin secretion. By enhancing these processes, it can support significant weight loss and better blood sugar control.
  • Approval and Usage: The oral version is approved by the FDA for weight management and is typically prescribed as part of a comprehensive weight loss plan that includes diet and exercise.
(more…)
Pharmacology / 06.08.2024

 

In today's fast-paced world, healthcare is moving toward more personalized and patient-centric approaches. This trend is evident in the increasing popularity of compounding pharmacies. These specialized pharmacies offer customized solutions tailored to individual patient's needs, making them an essential part of modern healthcare. While healthcare services are diverse and growing, the need for personalized medication is becoming more recognized. This article will explore the top benefits of custom compounding and why it's becoming a cornerstone of personalized healthcare.

Understanding Custom Compounding

Custom compounding refers to the creation of personalized medications by pharmacists to meet the unique needs of individual patients. Unlike traditional pharmacies that dispense mass-produced medications, compounding pharmacies prepare medications from scratch. This allows for a high degree of customization, ensuring that each medication is tailored specifically to the patient's requirements. The practice of compounding dates back to the origins of pharmacy, but it has gained renewed importance in modern healthcare as patients and providers seek more targeted treatment options. (more…)
Pharmacology / 02.07.2024

A Step-by-Step Guide for Emergency Prescription Refill

Do you rely on prescription medication? Then it’s important to know how to get an emergency prescription refill, whether due to travel, misplacing, or forgetting to get one. Here is a comprehensive guide covering all the necessary actions to ensure you receive your prescription on time and without stress.

What Is an Emergency Prescription?

Emergency prescription refills are used when a patient suddenly loses access to the needed medication. Common situations requiring emergency refills include:
  • While traveling, you forget to bring your prescription medication.
  • During your trip, your medication was misplaced or broken.
  • Even with the best-laid plans, you run out of medication and forget to schedule a refill.
  • You lost your prescription, especially as you moved into a new house or you live in a busy home.
  • Your prescribing physician is unavailable because of emergencies, holidays, or vacations.
  • Unexpected changes in your health that necessitate taking your prescription more frequently or at higher dosages (if that was discussed with a healthcare provider).
  • Refills for medications may be required immediately in the event of new health difficulties or consequences.
(more…)
Author Interviews, Cost of Health Care, Pharmacology / 09.12.2023

MedicalResearch.com Interview with: Joseph T. DiPiro, Pharm.D Associate Vice President, Faculty Affairs Virginia Commonwealth University Dr. DiPiro is an editor for Pharmacotherapy: A Pathophysiologic Approach MedicalResearch.com: What is the background for this study? Response: The ASHP/ASHP Foundation Pharmacy Forecast Report is constructed from a survey of health-system pharmacy leaders who were asked to rate the likelihood of events, scenarios, and trends occurring in the next five years. The purpose is for health-system pharmacists and pharmacy leaders to inform their strategic planning efforts. The Pharmacy Forecast is not intended to predict future events. Rather, the report is intended to be a provocative stimulant for the thinking, discussion, and planning that must take place in every health system. Leaders must be informed of potential developments to help position their organizations to care for patients, enhance population health, and improve medication outcomes. (more…)
Author Interviews, Cancer Research, Cost of Health Care, JAMA, Pharmacology / 17.11.2023

MedicalResearch.com Interview with: Lisa-Marie Smale, PharmD PhD Candidate Clinical Pharmacy Radboud University Medical Center Department of Pharmacy Nijmegen, the Netherlands Lisa-Marie Smale, PharmDPhD Candidate Clinical PharmacyRadboud University Medical CenterDepartment of PharmacyNijmegen, the Netherlands   MedicalResearch.com: What is the background for this study? Response: Cancer drugs are not always fully used by patients, while these drugs are mostly expensive and environmentally damaging, both in production and (waste) disposal. Therefore we investigated whether unused drugs of patients can be collected, verified of quality by a pharmacy, to be redispensed to other patients instead of being disposed of. We were interested whether such an approach ultimately leads to lower environmental impacts and costs. (more…)
Author Interviews, Cannabis, Pharmacology, Tobacco Research / 08.03.2023

MedicalResearch.com Interview with: Philip Lazarus, PhD Boeing Distinguished Professor, Pharmaceutical Sciences Professor, Dept of Pharmaceutical Sciences College of Pharmacy and Pharmaceutical Sciences Washington State University Spokane, WA 99210   MedicalResearch.com: What is the background for this study? Response: Smoking and tobacco use remains a major health issue. Smokers use cigarette over the course of the day because the levels of nicotine, the addictive agent in cigarettes and other forms of tobacco, dimmish with time in the bloodstream due to the breakdown of nicotine by enzymes in the body. By inhibiting the breakdown of nicotine in smokers, one would expect that the levels of nicotine would remain higher after smoking a single cigarette, and that these individuals may not require lighting up another cigarette so quickly, reducing the number of cigarettes smoked over the course of a day. This could have a profound effect on reducing the overall harm incurred from smoking or from using other forms of tobacco. In a single previous study, smokers who used a CBD inhaler exhibited a 40% reduction in cigarette use. In addition, while cannabis users are often smokers, previous studies have indicated that they smoke less cigarettes than non-cannabis-using cigarette smokers. In previous studies published in 2021, we found that major cannabinoids present in cannabis like THC and CBD inhibit major metabolizing enzymes in our body, including several that are important in drug metabolism. We hypothesized that CBD and its major active metabolite, 7-hydroxy (OH)-CBD, may also be inhibiting one or more of the enzymes important in the metabolism (or breakdown) of nicotine. (more…)