28 Oct Is It Mum Burnout or Perimenopause? The Signs Busy Mums Often Miss
Health Notice: Hormone replacement therapy, including bioidentical and pellet therapy, should only be prescribed and monitored by your healthcare provider. The Menopause Society and ACOG don’t recommend compounded pellets for routine use. The doses aren’t FDA-approved, can’t be adjusted or removed once placed, and can raise hormone levels too high. See a doctor promptly for very heavy or prolonged bleeding, bleeding between periods, or any bleeding after menopause as well as your regular checkups. If you are experiencing persistent low mood or thoughts of harming yourself, call or text 988 (Suicide & Crisis Lifeline) or text HOME to 741741 in the U.S.; in the UK, call Samaritans free on 116 123.
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It's 3 pm, and you've hit the wall. You've done the school run, answered a pile of work emails, tracked down a missing PE kit, and forgotten why you walked upstairs. By teatime, you're snapping at the kids over nothing, and at 3 a.m., you're wide awake with your mind racing. Most of us shrug and call it mum life. Yet hormone specialists, including the team at Bio Hormone Center, a physician-led hormone replacement clinic headed by board-certified gynecologist Dr. Michael Augustino, according to the clinic, list fatigue, brain fog, moodiness, and poor sleep among the most common signs of shifting hormones.
So if you're knackered in a way a lie-in never fixes, it's worth asking a different question. Is this burnout, or could it be perimenopause? The honest answer is that it can be both, and knowing the difference changes what actually helps.
Shani Vaknine[/caption]
Shani Vaknine, Ph.D. candidate
Brain and Behavioral Sciences
The Hebrew University
MedicalResearch.com: What is the background for this study?
Response: We’ve long known that maternal stress during pregnancy can affect her baby’s development, but the molecular mechanisms behind this remained unclear. In our study, we explored how psychosocial stress experienced by the mother in late pregnancy influences tiny molecular fragments in the newborn’s blood. These fragments, called transfer RNA fragments or tRFs, were considered for many years to be disposable, but have recently been shown to have important biological functions.
Dr. Ådén[/caption]
Ulrika Ådén PhD
Professor of Neonatology
Department of Women's and
Children's Health Karolinska
MedicalResearch.com: What is the background for this study?
Response: Children born preterm are at higher risk of cognitive impairment during childhood and later in life. However, an important unresolved question is whether these impairments primarily reflect genetic susceptibility or are driven by the biological consequences of being born too early. Cognitive development is known to have a strong heritable component (~70 %), and previous studies have attempted to disentangle genetic and environmental contributions, for example through sibling comparison designs. Although informative, such approaches have inherent limitations.
In this study, we aimed to investigate long-term cognitive outcomes across a range of gestational age groups including very preterm, moderately preterm, late preterm, and early term, compared to children born full term. Importantly, we accounted for genetic influences as well as a range of potential confounding factors, including prenatal risks and child-specific factors. This approach provides a more nuanced understanding of the extent to which cognitive outcomes associated with preterm birth reflect biological versus inherited risk.