In this interview, Dr. Brandon Claflin discusses modern interventional pain management and how personalized care helps patients manage chronic...
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Improving outcomes for patients living with chronic pain starts with an understanding of the latest research. Historically, chronic pain was treated with procedures and medication that dealt with the symptoms of pain, believed to stem from tissue or nerve damage.
Recent studies show that chronic pain is complex and requires a much deeper knowledge and empathy for your patients, even when there is no clear evidence of damage. This is due to understanding discomfort as centralized pain, where the brain and spinal cord become overly sensitive to pain signals.
Chronic pain requires whole-person care that uses shared therapies for coping skills, emotional regulation, lifestyle adjustments, and minimally invasive treatments. This article reviews the latest evidence on chronic pain to support a more informed outlook toward your patients.
Discover the safety benefits of state-regulated integrative medicine. Learn why obtaining a Medical Marijuana Card ensures legal protection and doctor-supervised...
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The elbow is arguably one of the most used joints in the body. It allows us to bend our arm, which means it is used for most daily activities. From scratching your noise to playing sports, your elbow is a necessity. This means that when something is wrong with your elbow, it can be extremely frustrating and seriously impact your quality of life. Unfortunately, it can be quite difficult to know which elbow condition you’re experiencing, as there are so many of them. Let’s take a look at some of the most common elbow ailments, to give you a better idea of what you might be dealing with.
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In today’s fast-moving world, people rely on innovative solutions that allow them to live, work, and move with confidence. Whether it’s supporting the body during recovery or protecting a building from unexpected emergencies, the right systems make all the difference.
That’s why companies like BioSkin and RAEL Fire Protection have become essential in their industries. One focuses on human mobility and comfort, and the other safeguards the places where we live and work. Together, they highlight the importance of proactive protection at every level.
Key Takeaways
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Joint pain is one of the most common health complaints worldwide, affecting millions of people every year. Whether caused by arthritis, tendon injuries, or degenerative conditions, persistent joint pain can significantly impact quality of life. For many patients, surgery is considered a last resort - and the good news is that advances in non-surgical treatments are providing more effective options than ever before.
In this article, we’ll explore some of the latest approaches to managing joint pain without surgery, and why patients are increasingly considering these treatments as part of a comprehensive care plan.
Dr. Baccarelli[/caption]
Statement from Andrea Baccarelli, MD, PhD
Dean of the Faculty
Professor of Environmental Health
Harvard T.H. Chan School of Public Health
Colleagues and I recently conducted a rigorous review, funded by a grant from the National Institutes of Health (NIH), of the potential risks of acetaminophen use during pregnancy. We reviewed 46 previously published human studies worldwide.
We found evidence of an association between exposure to acetaminophen during pregnancy and increased incidence of neurodevelopmental disorders in children. This association is strongest when acetaminophen is taken for four weeks or longer.
Dr. Jain[/caption]
MedicalResearch.com Interview with:
Rakesh Jain, MD, MPH
Clinical Professor at the Department of Psychiatry
Texas Tech University School of Medicine- Permian Basin
Midland, Texas
MedicalResearch.com: Would you briefly explain the condition of fibromyalgia? Whom does it primarily affect and what are the symptoms?
Response: Fibromyalgia is the prototypical example of a type of pain called nociplastic pain, or pain that comes from altered pain processing in the central nervous system. It is mainly characterized by widespread pain, non-restorative sleep, fatigue and cognitive impairment (brain fog). Over 10 million adults in the United States are affected by this disease, most of whom are women.
Dr. Gwarzo[/caption]
Ibrahim Gwarzo, DrPH, MPH, MBBS
Research Scientist at Nemours Children’s Health
Delaware Valley, Delaware USA
MedicalResearch.com: What is the background for this study? Would you briefly explain the condition of sickle cell disease and why young people frequently present to the ER with severe pain?
Response: Sickle cell disease is an inherited blood disorder that affects red blood cells. It is passed down as an autosomal recessive disorder, meaning a person must inherit the defective gene from both parents to have the disease. The condition primarily impacts hemoglobin, the protein responsible for carrying oxygen in red blood cells, which leads to changes in the shape and stability of these cells. The complications associated with the disease, including recurrent and severe pain episodes, are a direct result of these changes. These pain episodes are debilitating and unpredictable, resulting in frequent emergency department visits where they are typically treated with pain medications, including opioids. It is estimated that around 100,000 people in the United States have sickle cell disease, with about 40,000 being children. The disease has a significant prevalence in the Afro-Latino population.
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For decades, treating neuropathy has been an uphill battle. Patients have long relied on medications, pain management, and lifestyle changes to cope with the debilitating symptoms, numbness, tingling, burning pain, and muscle weakness, that come with nerve damage. While these approaches can provide relief, they rarely offer a path to true recovery.
But the future of neuropathy treatment is shifting, thanks to breakthroughs in regenerative medicine. This innovative field is transforming what was once a lifelong condition into something far more hopeful: a condition that may be treatable at its root.
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The FDA has now officially approved Journavx (generic name suzetrigine). This is a breakthrough non-narcotic pain medication that was developed to control pain, whether chronic pain, acute pain, or even cancer pain, without the addictive properties of traditional opioid medication. Touted as a safe option for patients with moderate to severe acute pain, this new pain drug is gaining attention for offering a non-opioid treatment option with minimal side effects and clinically proven results.
In this article, we will break down what Journavx is, what makes it different from non-opioid pain meditation, and what its FDA approval means for the future of pain management. We will also explore its application for nerve blocks, how it compares with other medications, and the key clinical data that led to this decision.
Knowing the difference between acute and chronic pain is key when it comes to choosing an appropriate treatment. Acute pain...
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Sciatica and lumbar pain continue to be among the most frequent causes of disability across the adult population. In 2020, approximately 619 million people worldwide suffered from low back pain. The World Health Organization (WHO) projects this figure to climb to 843 million by 2050.
These conditions frequently stem from lifestyle choices, aging, injuries, or spinal degeneration. Symptoms vary from slight discomfort to intense pain that can extend down the leg, often accompanied by numbness or muscle weakness.
Despite the variety of causes, the initial clinical response has often been the same. It starts with medication for pain, followed by imaging, and then consideration of invasive interventions for persistent cases.
However, a growing body of evidence suggests that many patients may find long-lasting relief through non-invasive methods when care is applied appropriately. As a result, healthcare providers are taking a second look at these therapies, reevaluating their role in both early and ongoing management.
Back pain is more than just discomfort—it can completely change how you live, move, and even sleep. Among the many spinal injuries people suffer, a herniated disc is one of the most common and misunderstood. And in many cases, it's not caused by age or genetics—it's the result of sudden, forceful trauma.
Nestled between Denver and Colorado Springs, Castle Rock blends small-town charm with rapid suburban growth. With its scenic trails, active lifestyle, and expanding roadways, accidents—especially those involving the spine—are unfortunately not uncommon. Understanding your legal rights here is just as important as seeking medical care.
If you believe your herniated disc was caused by someone else's negligence, don't ignore it. Getting help from an experienced professional like Casares Injury Law's Castle Rock herniated disc attorney could make all the difference in how your case is handled and how you recover.
Let's break down the types of accidents that commonly lead to herniated disc injuries and why they can be so serious.
Dr. Binshtok[/caption]
MedicalResearch.com Interview with:
Prof. Alexander Binshtok PhD
Cecile and Seymour Alpert Professor in Pain Research
Hebrew University’s Faculty of Medicine and Center for Brain Sciences (ELSC)
MedicalResearch.com: What is the background for this study?
Response: Paracetamol (also known as acetaminophen) is one of the world’s most commonly used pain relievers and fever reducers, yet for decades, its precise biological mechanism has remained something of a mystery. Traditionally, scientists believed its analgesic effect stemmed from central nervous system activity—specifically through the action of its metabolite, AM404, on cannabinoid and TRPV1 receptors in the brain.
Especially when it interferes with your ability to walk, run, or even comfortably stand, joint and tendon pain can be annoying. While slight discomfort usually goes away with rest or home care, prolonged pain could point to a more serious problem. See a Minneapolis foot and ankle doctor to get a professional assessment and treatment plan catered to your needs if you have been consistently uncomfortable in your lower limbs.
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Ohio’s medical marijuana program offers qualifying patients safe, state-regulated access to cannabis products for symptom relief and improved quality of life. Established by House Bill 523 in 2016, the Ohio Medical Marijuana Control Program (OMMCP) began licensed sales at dispensaries on January 16, 2019, under strict rules designed to protect patients and ensure product safety. Patients receive physician-certified cards from the Ohio Board of Pharmacy, allowing them to purchase low-THC or high-CBD products in non-smoking forms—only edibles, oils, vapors, patches, tinctures, or plant matter.
Qualifying Conditions
To be eligible, patients must have at least one of the 21 state-approved conditions. The original qualifying conditions include:
Struggling with lower back pain is common, as most of you who are working office jobs and for more than 8 hours per day can probably relate, I’ve come to understand just how important it is to take proactive steps to protect your spine.
Sitting for prolonged periods without proper support or movement can slowly wreak havoc on your posture, muscle balance, and overall comfort.
This guide walks you through five practical and effective steps you can implement right now to help prevent back pain while sitting at your desk, whether you’re working from home or in a traditional office setting.
Dr. Piper[/caption]
Brian J. Piper, PhD
Department of Medical Education
Center for Pharmacy Innovation & Outcomes
Geisinger College of Health Sciences
Scranton, PA 18509
MedicalResearch.com: What is the background for this study?
Dr. Piper: Tapentadol has an unusual mechanism of action. This opioid is similar to morphine in that it activates mu, the main opiate receptor which is important for pain. This drug also acts similar to an antidepressant like duloxetine (Cymbalta) with equal ability to block both the norepinephrine and the serotonin transporters (Figure 1). The combination of opioid and monoaminergic activity may influence both therapeutic and side effect profiles.
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Figure 1. Biological mechanism of action of the atypical opioid tapentadol involves binding to the mu opiate receptor, blocking the norepinephrine transporter (NET), and blocking the serotonin transporter (SERT) [1].[/caption]Tapentadol is approved in the US for moderate to severe acute pain, moderate to severe chronic pain, and neuropathic pain associated with diabetic peripheral neuropathy. However, tapentadol is not generally considered first-line for any of these indications. Although this agent has a high potential for abuse and is classified as a Schedule II substance, a manufacturer of extended release tapentadol (Grunenthal) has conducted a misinformation campaign claiming tapentadol has a “minimum potential of abuse”, does not cause respiratory depression (a well-known opioid effect), does not cause any euphoric feelings, has no street value, and is not an opioid [2]. Prior pharmacoepidemiological studies have examined the use patterns of other prescription opioids that can be misused like oxycodone [3], fentanyl [4], meperidine [5] and methadone [6] but there is limited national information about the use of tapentadol.
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You fight through the appointments, the scans, the treatments, and then—when it’s supposed to be over—your body still feels off. For many cancer survivors, especially those who went through chemotherapy, neuropathy doesn’t just fade away. Sometimes it lingers, sometimes it gets worse, and sometimes it shows up in ways that completely change how you move. If you’re dealing with drop foot or numbness, burning, or pain in your feet, you’re not imagining it. You’re not alone. And while it’s incredibly frustrating, there are real things that can help.
Understanding What’s Happening To Your Feet
Post-cancer neuropathy isn’t just annoying—it can be debilitating. It usually starts because certain chemo drugs damage the nerves, especially in your hands and feet. This damage can mess with how your muscles and nerves talk to each other. So when your brain says “lift your foot,” your body doesn’t always get the message right.
Drop foot is one of the more obvious results of that disconnect. It feels like your foot is dragging or slapping the ground when you walk. You might start tripping more, feel unsteady, or start avoiding certain shoes altogether. For others, the issue isn’t how the foot moves but how it feels—like walking on pins and needles, or not feeling it at all. Both are forms of neuropathy, and both can stick around long after treatment ends.
The tricky part is that this isn’t something you can just walk off. It’s not about needing to stretch more or push harder. These symptoms come from actual nerve damage, which doesn’t always heal quickly—or fully.
Dr. Streicher[/caption]
John M. Streicher, PhD
Professor, Neuroscience - GIDP
Professor, Pharmacology
College of Medicine Tucson
Pharmacology
University of Arizona
MedicalResearch.com: What is the background for this study?
Response: We first started studying terpenes around 2019, when my student Justin LaVigne became interested in these molecules and their potential interaction with cannabinoids and other chemicals in cannabis, the so-called “entourage effect.”
The literature at the time showed that terpenes could be beneficial in pain relief and other indications, in both animal and human studies; however, there were limits to the literature, such as a lack of investigation into therapeutic features like side effects and a relative lack of detailed molecular mechanisms. We started by testing 5 purified terpenes in mice, geraniol, linalool, beta-caryophyllene, alpha-humulene, and beta-pinene. We found they had a “cannabimimetic” effect in that they produced behaviors much like cannabinoids, but not through the cannabinoid receptors. This was published in 2021.
Neuropathy is a debilitating condition that affects millions of people worldwide, causing discomfort, pain, and a significant reduction in quality of life. Fortunately, modern advancements in medical research have opened doors to innovative treatments that offer hope and healing to neuropathy sufferers. With a focus on the latest breakthroughs and expert recommendations, we will learn about neuropathy, its symptoms, and cutting-edge treatment options that are helping patients regain comfort and mobility.
Understanding Neuropathy and Its Symptoms
Neuropathy, often termed peripheral neuropathy, refers to a series of disorders resulting from damage to the peripheral nerves. These nerves are responsible for transmitting signals between your brain, spinal cord, and the rest of your body. Symptoms of neuropathy can vary widely and may include numbness, tingling, burning sensations, muscle weakness, and even sharp pains. Left untreated, these symptoms can lead to more severe complications, such as infections and balance issues. Identifying neuropathy early and seeking professional guidance is crucial for managing and mitigating its effects.
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A sudden jolt, a screech of tires, and everything changes instantly.
Head and neck injuries often follow car accidents, leaving victims in pain and uncertainty. These injuries range from mild whiplash to severe trauma, impacting daily life, work, and overall well-being.
Legal guidance becomes essential in major urban centers where traffic congestion increases the risk of accidents. A car accident lawyer can help victims win compensation for medical expenses, lost wages, and long-term care.
In this post, we break down the critical actions to take after sustaining a head or neck injury in a car crash.
Chiropractic care offers a minimally invasive solution to musculoskeletal issues. Back, neck, and joint pain are some reasons people turn to chiropractic care. Through the alignment of the spinal column, the care promotes overall health. Repeating the treatments increase the function in the body and reduce the use of medication.
Beyond pain reduction, chiropractic care also ensures overall health by aiding nervous function. A well-aligned spinal column provides good communication between the body and the brain. A misaligned spinal column, in contrast, squishes the nervous tissues, resulting in discomfort and less function. Through the maintenance in spinal health, most people feel improved rest, improved digestive function, and improved energy.
One of the most powerful chiropractic treatments lies in the body's ability to heal from illness if only given the support necessary. Rather than simply masking the symptom through medication, this integrated approach targets the root cause of the discomfort. Patients typically suffer from less frequent and less painful episodes if proper care is administered. This makes the operation appealing to individuals who desire long-term remedy and who want to eliminate surgical intervention.
While most people think of it as a form of torture, for others it symbolizes the pain of sleep unfulfilled. Whether due to work stress, bad posture, or recent trauma, the anguish is almost unbearable. But the good thing is that there are many easy-to-follow home remedies in the pharmacy of nature. Here are some home remedies that will help ease the pain in your neck and back so that you feel better fast.
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Medicinal cannabis is a revolutionary approach to pain management, particularly in patients where conventional medications fail to offer them adequate relief or create intolerable side effects. With ongoing research on cannabis and its medicinal properties, its effectiveness for pain relief has become more convincing. Here are some reasons why medicinal cannabis has risen in popularity in pain management.
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An important aspect of medicine a variety of physiotherapy treatments put to use in today’s world. It has historically been proven to help restore movement and function while reducing pain in targeted areas.
When it comes to the realm of rehabilitation for the body, physiotherapy is essentially always a part of the process. Another reason why it’s so popular is that it’s non-invasive, and can take a diverse approach to treatment options. This article discusses the different types of physiotherapy treatments and what makes them so useful.
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A car accident is a traumatizing experience. The aftermath often leaves victims shaken and stressed. Although a few injuries, such as broken bones, cuts, or bruises, can be immediately felt. Many do not feel any pain immediately after an accident, thus giving them an illusion of safety.
Delayed pain and other symptoms can appear hours, days, or even weeks after an accident, making it easy to underestimate the severity of the injury. Car accident victims must understand what delayed pain is and why it occurs. That knowledge is critical to ensure that they receive proper treatment. What is Delayed Pain? Delayed pain is discomfort that develops after an accident, typically showing up after a few hours or days. It can range from soreness and stiffness to more severe neck, back, shoulder, or internal pain. Some common delayed pain conditions include whiplash, muscle strains, ligament injuries, herniated discs, and concussions.
Combining mind-body techniques with other osteoarthritis treatments is generally safe, but it’s important to consult with healthcare providers. Some techniques,...