#epidemiology, Author Interviews, UCSD / 06.02.2026

MedicalResearch.com Interview with: [caption id="attachment_72295" align="alignleft" width="150"]Raphael Cuomo Dr. Cuomo[/caption] Raphael E. Cuomo, PhD Professor of Medicine Associate Adjunct Professor, Anesthesiology University of California, San Diego MedicalResearch.com: What is the background for this study? Response: Epidemiology has mostly been built to explain who gets sick, but many of the decisions that matter most happen after diagnosis. Across multiple diseases, relationships that look consistent in prevention studies often do not hold once people already have the disease, and sometimes they even flip. Diagnosis can change patient biology, treatment context, and biases in the data, so we need clearer methods and language for postdiagnosis questions.
Alzheimer's - Dementia, Author Interviews, Cannabis / 06.02.2026

Editor's note: Do Not Use these products alone or in combination without the specific guidance of your health are provider, due to risks of untoward side effects. THC/CBD and other cannabis products should not be used if you are pregnant, planning to become pregnant or nursing. Children should not be exposed to cannabis in any form. MedicalResearch.com Interview with: [caption id="attachment_72277" align="alignleft" width="200"]Chu Chen, PhDProfessor and Joe R. and Teresa Lozano Long Chair in Neural Physiology Department of Cellular and Integrative Physiology Center for Biomedical Neuroscience Joe R. and Teresa Lozano Long School of Medicine University of Texas at San Antonio Health Science Center San Antonio, TX 78229 Prof. Chu Chen[/caption] Chu Chen, PhD Professor and Joe R. and Teresa Lozano Long Chair in Neural Physiology Department of Cellular and Integrative Physiology Center for Biomedical Neuroscience Joe R. and Teresa Lozano Long School of Medicine University of Texas at San Antonio Health Science Center San Antonio, TX 78229 MedicalResearch.com: What is the background for this study? Response: Alzheimer’s disease (AD) is the most common cause of dementia in the elderly, yet no effective therapies currently exist to prevent, treat, or halt its progression. Cannabis has been used for thousands of years for both recreational and medicinal purposes; however, its therapeutic application has been limited by undesirable neurocognitive side effects, particularly impairments in learning and memory. Δ9-Tetrahydrocannabinol (Δ9-THC), the primary psychoactive component of cannabis, has been shown to reduce amyloid-β (Aβ) pathology in animal models of AD, but at high doses (>5.0 mg/kg) it also disrupts synaptic function and impairs cognition. Research from our laboratory and others has demonstrated that Δ9-THC-induced deficits in long-term synaptic plasticity, learning, and memory are associated with the induction of cyclooxygenase-2 (COX-2), an inducible enzyme that converts arachidonic acid into pro-inflammatory prostaglandins. Notably, pharmacological inhibition or genetic deletion of COX-2 attenuates Δ9-THC-induced synaptic and cognitive impairments. Based on these findings, we proposed a combination (“cocktail”) therapy consisting of low-dose Δ9-THC and the anti-inflammatory drug celecoxib, a selective COX-2 inhibitor, as a potential therapeutic strategy for AD. This approach is designed to preserve the beneficial effects of Δ9-THC while minimizing its adverse neurocognitive effects and COX-2-mediated inflammatory responses.
Author Interviews, Autism, BMJ, Parkinson's / 05.02.2026

MedicalResearch.com Interview with: [caption id="attachment_72249" align="alignleft" width="150"]Dr. Caroline Fyfe PhDPostdoctoral Research Associate Life Long Health and Wellbeing Theme University of Edinburgh Dr. Fyfe[/caption] Dr. Caroline Fyfe PhD Postdoctoral Research Associate Life Long Health and Wellbeing Theme University of Edinburgh MedicalResearch.com: What is the background for this study? Response: Autism (ASD) has traditionally been seen as a condition that disproportionately affects males. This study quantifies the sex bias across birth cohorts, ages, and calendar time,  using the Swedish national population registers to follow ~ 2.7 million individual born between 1985 and 2020 throughout their lives. Among children under ten years old the male-to-female diagnosis ratio remained relatively stable at about 3:1. In contrast, a rapid increase in diagnoses of ASD among females during adolescence, produced a “female catch-up effect” that resulted in near parity of ASD prevalence between males and females by adulthood.
Author Interviews, Leukemia / 04.02.2026

Chronic lymphocytic leukemia, or CLL, and small lymphocytic lymphoma, or SLL, are chronic B cell cancers that often need long term treatment. Many patients are older at diagnosis or have other medical conditions, so the choice of first line therapy is important. Over time the goal is not only to control disease but also to preserve quality of life while keeping side effects manageable. Targeted therapies have changed how CLL and SLL are treated. Bruton tyrosine kinase (BTK) inhibitors are now commonly used because they offer oral treatment and avoid traditional chemotherapy. Zanubrutinib is a covalent BTK inhibitor that has been studied a lot in the frontline setting. Long term results from the SEQUOIA zanubrutinib study phase 3 PFS data give useful insight into how this approach performs over time compared with chemoimmunotherapy.
Addiction, Author Interviews, Cannabis / 02.02.2026

MedicalResearch.com Interview with: [caption id="attachment_72231" align="alignleft" width="200"]Saji George PhDAssociate Professor & Chair, Department of Food Science and Agricultural Chemistry Canada Research Chair in Sustainable Nanotechnology for Food and Agriculture Faculty of Agricultural and Environmental Sciences, McGill University Quebec, Canada Dr. Saji George[/caption] Saji George PhD Associate Professor & Chair, Department of Food Science and Agricultural Chemistry Canada Research Chair in Sustainable Nanotechnology for Food and Agriculture Faculty of Agricultural and Environmental Sciences, McGill University Quebec, Canada MedicalResearch.com: What is the background for this study? Response: Cannabis plants are highly susceptible to microbial contamination, particularly by fungi producing harmful mycotoxins. Infection of plants by fungal pathogens could result in the contamination of cannabis products with mycotoxins that pose serious health risks, especially for immunocompromised patients who use cannabis for medical purposes. Currently industry employ decontamination methods such as gamma irradiation to clean up cannabis products likely to harbor fungi and their metabolites. However, their effectiveness in fully eliminating toxigenic fungi and associated mycotoxins remains unclear. Our studies aimed to evaluate the persistence of fungi and mycotoxins in dried cannabis buds following gamma irradiation, using a combination of culture-based, molecular, and immunological techniques. These studies revealed that complete sterilization of cannabis buds once contaminated with mycotoxin is extremely difficult and highlighted the importance of early interventions in preventing toxigenic fungi during cultivation.
Author Interviews, OBGYNE / 02.02.2026

Editor's note: Please let your health care provider know if you are experiencing night sweats, whether you or not you are pregnant. Experiencing night sweats early pregnancy sign symptoms can be surprising and uncomfortable, especially if you’re still waiting for that positive test or just beginning your first trimester. Many women wake up drenched, overheated, or restless during early pregnancy without realizing that this very common symptom is often linked to hormonal changes. While uncomfortable, night sweats at this stage are usually harmless and reflect your body’s rapid adjustments as pregnancy begins. As your hormones shift, the right sleep setup can make a huge difference. A supportive maternity pillow can help regulate airflow around your body, improve sleep posture, and reduce overheating caused by restless sleep. Understanding why night sweats happen and how to manage them can help you stay comfortable and confident through these early changes. Night Sweats as an Early Pregnancy Sign The Hormonal Rollercoaster: Why Progesterone and Estrogen Cause Temperature Swings Hormones are the most common reason for early pregnancy night sweats. Right after conception, your body rapidly increases its production of progesterone and estrogen, both of which directly influence your temperature regulation.

Here’s how hormones trigger night sweats:

  • Progesterone naturally raises body temperature
  • Estrogen fluctuations affect heat sensitivity
  • These hormones stimulate your metabolism
  • Your body works harder to support the uterine lining
This creates a warming effect that becomes more noticeable at night when your body is naturally trying to cool down. Hormone-driven temperature swings are perfectly normal and often one of the earliest signs of pregnancy.
Author Interviews / 02.02.2026

[caption id="attachment_72222" align="aligncenter" width="500"]michigan-accidental-death-lawyers.jpg Freepix image[/caption] A sudden loss hits like a door slamming in the middle of a quiet house. One minute, life is normal. Next, everything is split into “before” and “after.” And after the shock starts to wear off, the questions creep in. What actually happened? Could this have been prevented? And, awkward as it feels to even say out loud, what happens now for the people left behind? A death can sometimes become more than a personal catastrophe. It can become a legal claim. Not because anyone is trying to “cash in,” but because the law recognizes something pretty simple: when someone’s negligence ends a life, the fallout doesn’t disappear. Bills still arrive. Kids still need support. A partner still loses companionship, help, income, and stability. It’s a lot. So let’s talk about how wrongful death cases work in Michigan, in plain language, without the weird courtroom fog.
Author Interviews, Cancer Research / 31.01.2026

MedicalResearch.com Interview with: [caption id="attachment_72207" align="alignleft" width="400"]Prof. Yeoh Khay Guan & Prof Patrick Tan Prof. Yeoh Khay Guan & Prof Patrick Tan[/caption] Professor Patrick Tan, MD PhD Dean, Duke-NUS Medical School; Cancer and Stem Cell Biology Signature Research Programme, Duke-NUS Medical School; and Professor Yeoh Khay Guan, MBBS Chief Executive, National University Health System; Senior Consultant Division of Gastroenterology and Hepatology National University Hospital.   MedicalResearch.com: What is the background for this study? Response: Gastric intestinal metaplasia (IM) is a precancerous condition that can arise in the stomach after long-term infection with Helicobacter pylori (a common stomach bacterium). Clinically, IM is recognised as a risk state for gastric cancer (GC), as individuals with IM have 6-fold higher risk of eventually developing GC. However, not all IM patients will develop GC, and we lack an understanding of the biological processes operating within IM to transition to GC. Also, we don’t know if these processes are commonly found across the world, particularly since different countries have different rates of GC incidence. In this study, we looked at DNA mutations and mutational signatures in IM samples collected from six countries with varying GC incidence (including accompanying blood-derived genetic variants). We wanted to understand potential risk factors for GC and how this information can be harnessed to improve the clinical management of IM patients and to reduce their GC risk.
AI and HealthCare, Author Interviews, Brain Cancer - Brain Tumors, Lancet, Mammograms / 30.01.2026

MedicalResearch.com Interview with: [caption id="attachment_72182" align="alignleft" width="200"]Kristina Lång MD PhDAssociate professor, Diagnostic Radiology Translational Medicine, Lund University Senior consultant, Unilabs Mammography Unit Skåne University Hospital, Malmö, Sweden Dr. Lång[/caption] Kristina Lång MD PhD Associate professor, Diagnostic Radiology Translational Medicine, Lund University Senior consultant, Unilabs Mammography Unit Skåne University Hospital, Malmö, Sweden MedicalResearch.com: What is the background for this study? Response:  Prior to the start of the trial, several retrospective studies had shown that AI could discriminate between screening mammograms at low and high risk of cancer, with performance comparable to that of average breast radiologists. These findings suggested a potential to improve both the efficiency and sensitivity of mammography screening. This motivated us to design and evaluate an AI-supported screening procedure in a randomised controlled trial. The MASAI trial was among the first prospective studies in this field and, to date, remains the only randomised trial with reported results on the use of AI in breast cancer screening. In European breast cancer screening programmes, every mammogram is usually read by two radiologists, so called double reading, to ensure a high sensitivity. In the MASAI trial we compared AI-supported mammography screening to standard double reading without AI. I n the AI-supported approach, mammograms identified as low-risk by the AI were read by a single radiologist, while high-risk mammograms underwent double reading, with AI providing additional detection support.
Author Interviews, Electronic Records, General Medicine / 29.01.2026

[caption id="attachment_72178" align="aligncenter" width="500"]electronic-primary-care-notes.jpg Freepix image[/caption] Family medicine is busy every single day. Patients come in with many concerns at once. Notes must be written for every visit. Follow-ups need to be clear and complete. This work takes a lot of time. Medical Documentation Automation is starting to make this easier.

The Daily Reality of Primary Care Notes

Family doctors handle many visit types. Some visits are short. Some are long and complex. Chronic care visits need careful tracking. Preventive visits need clear records. Writing all of this by hand is tiring. This is where documentation automation helps.
Annals Internal Medicine, Author Interviews, Kidney Disease / 28.01.2026

[caption id="attachment_72168" align="alignleft" width="150"]Dustin Mark, MDEmergency Medicine/Critical Care Medicine, East Bay
Adjunct Researcher, KPNC Division of Research, CREST Network Dr. Mark[/caption] MedicalResearch.com Interview with: Dustin Mark, MD Emergency Medicine/Critical Care Medicine, East Bay Adjunct Researcher, KPNC Division of Research, CREST Network MedicalResearch.com: What is the background for this study? Response: We examined medical records from 13,988 adults hospitalized with severe hyponatremia between 2008 and 2023 across 21 community hospitals in the Kaiser Permanente Northern California health system. Patients were grouped based on how quickly their sodium levels were corrected within a 24-hour period (< 8 meq/L, 8-12 meq/L, > 12 meq/L) and were followed for up to 90 days. The primary outcome was death or serious delayed neurologic events, such as brain damage, seizures, paralysis, or altered consciousness. The results suggest that there is likely a true independent association between slow sodium correction and adverse outcomes, and that current guidelines promoting slow correction of sodium levels should be re-evaluated accordingly.
Accidents & Violence, Author Interviews / 28.01.2026

[caption id="attachment_72162" align="aligncenter" width="500"]reducing-pressure-ulcers-long-term-care.jpg Freepix[/caption] Pressure injuries, also known as bedsores or pressure ulcers, are a serious health concern in long-term care settings, especially among elderly individuals with limited mobility. They result from prolonged pressure on the skin and underlying tissues, typically over bony areas such as the sacrum, hips, and heels. Preventing these injuries is essential to maintaining comfort, mobility, and overall well-being in care environments. Below are practical, evidence-based strategies to help reduce the risk of pressure injuries in long-term care.

Use Appropriate Support Surfaces to Minimise Pressure

The right bedding and cushioning solutions can significantly reduce the risk of skin breakdown. In long-term care settings, standard mattresses are often inadequate for those at high risk. Alternatives such as alternating pressure mattresses, static air overlays, or foam pressure-relief surfaces help distribute weight more evenly and reduce sustained pressure on vulnerable areas. Caregivers and facility managers should regularly assess and upgrade bedding solutions where necessary. A wide range of  pressure care mattress options for pressure injury management are available to support different levels of risk and mobility, from preventative overlays to active therapeutic systems.
Author Interviews / 28.01.2026

MedicalResearch.com Interview with: [caption id="attachment_72153" align="alignleft" width="200"]Kymora B. Scotland MD, PhDAssistant Professor Department of Urology UCLA Gerard Wong PhD, Professor Bioengineering Dept., Chemistry & Biochemistry Dept., Microbiology, Immunology, & Molecular Genetics Dept. California NanoSystems Institute UCLA Los Angeles, CA  Dr. Scotland[/caption] Kymora B. Scotland MD, PhD Assistant Professor Department of Urology UCLA Gerard Wong PhD, Professor Bioengineering Dept., Chemistry & Biochemistry Dept., Microbiology, Immunology, & Molecular Genetics Dept. California NanoSystems Institute UCLA Los Angeles, CA MedicalResearch.com: What is thebackground for this study? Response: Because of Dr. Scotland’s clinical work taking care of patients with kidney stones, we noticed that sometimes patients with no history of urinary tract injections would develop UTIs or even sepsis after stone surgery. Similarly, when we cultured the stones obtained from surgical procedures - again in patients without a history of UTIs- we would often identify bacteria. This led us to hypothesize that bacteria actually play a role in stone formation and were not just bystanders occasionally found in the kidney.
Author Interviews, Medical Devices / 26.01.2026

[caption id="attachment_72144" align="aligncenter" width="500"]medical-device-design.jpg Photo by National Cancer Institute on Unsplash[/caption] Medical innovation often focuses on breakthrough technology, new materials, and advanced diagnostics. While these elements matter, the design of medical devices plays an equally critical role in how safely and effectively those innovations are used. From handheld diagnostic tools to large clinical systems, design decisions influence usability, error rates, and patient trust in ways that extend beyond technical performance. Medical device design exists at the intersection of engineering, clinical workflow, and human behavior. When done well, it supports clinicians in delivering care while reducing unnecessary risks. When overlooked, it can introduce confusion, misuse, or unintended harm. As healthcare systems grow more complex, the importance of thoughtful, human-centered design continues to increase.

Patient Safety Begins Long Before Clinical Use

Patient safety is often discussed in terms of protocols, training, and regulatory compliance. However, many safety outcomes are determined long before a device reaches a hospital or clinic. Design choices made during early development stages affect how devices are handled, interpreted, and trusted in real-world settings. For example, poorly designed interfaces can increase the likelihood of user error, even among experienced clinicians. Ambiguous labeling, confusing controls, or non-intuitive layouts can slow response times or lead to misinterpretation. In high-pressure environments such as emergency departments or operating rooms, even small design inefficiencies can have serious consequences. By prioritizing clarity and usability during design, manufacturers can reduce the cognitive load placed on healthcare professionals and improve consistency in patient care.
Alcohol, Author Interviews, Cannabis / 26.01.2026

Editors' note: Cannabis and THCA/HEMP CBD products should have an active ingredient list on the container and have a Certificate of Analysis (COA). Discuss your use of THC, Cannabis or CBD products with your health care provider.  Dosing of CBD is variable, especially since it is not FDA regulated. Cannabis/CBD may interfere with other medications and should not be used in individuals with certain health conditions, including liver issues.  Do not use Cannabis products including edibles, drinks or CBD if you are pregnant, nursing or may become pregnant. Do not use cannabis products if driving or operating difficult or dangerous machinery. Children should not be exposed to cannabis or CBD products. It is unknown whether the effects of alcohol plus cannabis are cumulative and users ingesting both products should be especially cautious to avoid driving or other activities requiring alertness and judgement. MedicalResearch.com Interview with: [caption id="attachment_72135" align="alignleft" width="100"]Dr. Kruger Ph.D. Dr. Kruger .[/caption] Daniel J. Kruger, PhD Population Studies Center, Institute for Social Research University of Michigan [caption id="attachment_72136" align="alignleft" width="100"]Dr. Jessica Kruger Ph.D. Dr. Kruger[/caption] MedicalResearch.com: What is the background for this study? [caption id="attachment_72137" align="alignleft" width="100"]Dr. Nicholas Felicione Dr. Felicione[/caption] Response: Alcohol consumption, especially heavy alcohol consumption, is associated with many health risks and nearly 200 different health conditions and diseases. Reducing alcohol consumption reduces the risks and harms from alcohol. Previous research has demonstrated that people have reduced their alcohol consumption when they have access to cannabis. Cannabis beverages have emerged in States where cannabis is legal for adult or medical use.
Author Interviews, Electronic Records, Medical Billing / 26.01.2026

[caption id="attachment_72121" align="aligncenter" width="500"]efficient-medical-office-billing.jpg Freepix[/caption] Doctors' offices are not short on responsibility. They manage patient care, compliance, staffing, technology, and the constant churn of insurance rules, all while trying to keep the lights on and the waiting room moving. What often gets less attention is how many of their daily headaches are not clinical at all. They are operational. The good news is that some of the most meaningful improvements happening in medical practices right now are practical, measurable, and rooted in better systems rather than bigger budgets. When Administrative Friction Becomes a Care Issue Front office inefficiencies do more than slow down billing. They ripple outward. A denied claim delays revenue, which stresses staffing. Staffing stress shortens visits. Short visits frustrate patients. None of that helps outcomes, and none of it reflects a lack of effort from medical teams. It reflects a system that asks doctors offices to function like data companies without giving them the right tools. Eligibility errors are a perfect example. Verifying provider credentials across multiple states, plans, and licensing bodies is not glamorous work, but mistakes are costly. Automation and smarter data access are changing that reality. Practices that adopt healthcare payment integrity solutions that boost your payment integrity program with real-time provider eligibility data for all licensed providers across every U.S. state and jurisdiction are seeing fewer denials, faster reimbursements, and far less back and forth with payers. That efficiency shows up directly on the balance sheet, and indirectly in calmer days for staff.
Author Interviews, Infections / 22.01.2026

[caption id="attachment_72087" align="aligncenter" width="500"]hand-hygiene-after-discharge.jpg Photo by Burst[/caption] Leaving the hospital is often a relief, but for many patients, it also marks the start of a critical recovery phase. Once home, the responsibility for infection prevention shifts largely from clinical staff to patients and caregivers. This transition can be challenging, especially for individuals recovering from surgery, managing chronic illness, or living with weakened immune systems. Reducing infection risk at home is not about recreating a hospital environment. It’s about understanding where risks exist, how infections spread, and what practical steps make the biggest difference during recovery.

Why the Post-Discharge Period Is High Risk

Hospital discharge does not mean infection risk disappears. In fact, the days and weeks following discharge are when many infections emerge. Surgical wounds are still healing, medical devices may still be in use, and the immune system may be compromised by illness or treatment. According to the Centers for Disease Control and Prevention, about 1 in 31 hospital patients has at least one healthcare-associated infection on any given day, and a significant number of infections are identified after patients return home. Understanding this risk helps patients and families take prevention seriously without becoming overly anxious.
Alzheimer's - Dementia, Author Interviews, Lipids, Vanderbilt / 18.01.2026

MedicalResearch.com Interview with: [caption id="attachment_72035" align="alignleft" width="200"]Leslie S. Gaynor, PhDClinical Neuropsychologist & Assistant Professor of Medicine
Division of Geriatric Medicine
Department of Medicine
Vanderbilt University Medical Center
Nashville, TN 37203 Dr. Gaynor[/caption] Leslie S. Gaynor, PhD Clinical Neuropsychologist & Assistant Professor of Medicine Division of Geriatric Medicine Department of Medicine Vanderbilt University Medical Center Nashville, TN 37203 MedicalResearch.com: What is the background for this study? Response: The US population is rapidly aging, and the oldest members of our population are also the most vulnerable to developing clinical dementia. We are interested in studying older adults ages 80+ who display cognitive resilience despite this increased risk of dementia and actually display exceptional memory performance compared to their same-aged, typically performing peers. These “SuperAgers,”—i.e., 80+-year-old adults with memory performance that is comparable to or surpasses that of adults 20 to 30 years their junior—may hold the key to uncovering genetic factors that predict exceptionally healthy longevity.
Author Interviews, Autism, Nature / 16.01.2026

MedicalResearch.com Interview with: [caption id="attachment_72018" align="alignleft" width="200"]Andrey Vyshedskiy, Ph.D.Neuroscientist from Boston University Dr. Vyshedskiy[/caption] Andrey Vyshedskiy, Ph.D. Neuroscientist from Boston University MedicalResearch.com: What is the background for this study? What are the main findings? Response: Certain conditions, such as autism and Down syndrome, can limit a child’s ability to develop full language comprehension. In these cases, children often become “stuck” at a specific, quantized level of understanding:
  • Command Phenotype: Individuals at this level understand single words and simple commands but have difficulty combining nouns with adjectives or interpreting more complex instructions.
  • Modifier Phenotype: Individuals at this level can comprehend combinations of nouns and adjectives—for example, they can identify a small yellow pencil among pencils, straws, and Lego pieces of varying sizes and colors. However, they struggle with more complex language structures, such as sentences containing spatial prepositions, possessive pronouns, verb tenses, and narratives like fairy tales.
  • Syntactic Phenotype: Most children naturally progress to this most-advanced level of comprehension, characterized by the ability to understand full syntactic structures and more sophisticated language forms.
While the Command and Syntactic Phenotypes were anticipated by linguistics and developmental psychology, the distinct Modifier Phenotype was unexpected. Across several studies involving nearly 100,000 participants, these three phenotypes consistently emerged. Together with a recent longitudinal study of language development in over 15,000 participants, these findings highlight the critical importance of early engagement in syntactic conversations for the acquisition of the Syntactic Phenotype.
Aging, Author Interviews, Exercise - Fitness / 15.01.2026

[caption id="attachment_72010" align="alignleft" width="500"]DUK_NUS-Labteam members.jpg Cancer and Stem Cell Biology Duke-NUS Medical School Lab Team Members[/caption] MedicalResearch.com Interview with: Hung-Wen Tang, PhD Assistant Professor Cancer and Stem Cell Biology Duke-NUS Medical School Singapore MedicalResearch.com: What is the background for this study? Response: As we age, we naturally lose muscle strength and function — a condition known as sarcopenia. This makes everyday activities harder and increases the risk of falls, frailty, and loss of independence. Scientists have long known that a growth pathway in muscle cells called mTORC1 becomes overactive with age and contributes to muscle decline. However, the underlying cause of this overactivation remained unclear.
Aging, Author Interviews, Exercise - Fitness, Lancet / 14.01.2026

[caption id="attachment_71987" align="alignleft" width="200"]Ulf Ekelund Ph.D.Department of Sport Medicine, NSSS Oslo, Norway and Norwegian Institute of Public Health, Oslo Prof. Ekelund[/caption] MedicalResearch.com Interview with: Ulf Ekelund Ph.D. Department of Sport Medicine, NSSS Oslo, Norway and Norwegian Institute of Public Health, Oslo MedicalResearch.com: What is the background for this study? What are the main findings? Response:  Previous research including our own (Dose-response associations between accelerometry measured physical activity and sedentary time and all cause mortality: systematic review and harmonised meta-analysis | The BMJ) have shown that physical activity of any intensity reduces the risk for all-cause mortality. However, it is unclear how many deaths can potentially be averted by small and realistic increases in physical activity. We estimated that 6% and 10% of all deaths might be preventable is all individuals in two hypothetical intervention scenarios increased their time in moderate to vigorous intensity activity by 5 min per day. The two scenarios were a “high-risk” comprising the least active 20% of the population and a “population based” approach comprising all but the most active 20% of the population (i.e. 80%). We also estimated that reducing sedentary time by 30 min/day might prevent 3·0% of all deaths in the high-risk approach and 7·3% in the population-based approach.  Our results should be interpreted as if all individuals increased their levels of physical activity by 5 min per day, 6% and 10% of all deaths might be preventable in the two risk scenarios, respectively. This does not mean that the individual risk is reduced by these percentages from small increases in physical activity, since individuals respond differently to increasing their activity levels.
Author Interviews, CMAJ, End of Life Care / 12.01.2026

MedicalResearch.com Interview with: [caption id="attachment_71968" align="alignleft" width="200"]Sally Thorne RN, PhD, FAAN, FCAHS, FCAN, CMProfessor Emeritus, School of Nursing Dr. Thorne[/caption] Sally Thorne RN, PhD, FAAN, FCAHS, FCAN, CM Professor Emeritus, School of Nursing Co-Principal Investigator with : [caption id="attachment_71969" align="alignleft" width="133"]Dr. Barbara Pesut PhD, RNProfessor in the School of Nursing  Principal Research Chair in Palliative and End of Life Care Dr. Pesut[/caption] Dr. Barbara Pesut PhD, RN Professor in the School of Nursing Principal Research Chair in Palliative and End of Life Care University of British Columbia       MedicalResearch.com: What is the background for this study? Response: Medical assistance in dying (MAiD) was legalized in Canada in June of 2016 for Canadians who were facing a reasonably foreseeable natural death and met an explicit set of eligibility criteria as determined by qualified health care providers (physicians or nurse practitioners). In 2021, the legislation was extended to include the possibility of MAiD for persons who were suffering from a ‘grievous and irremediable’ medical condition but for whom natural death was not immediately foreseeable. As assisted dying represented a significant change in available options for Canadians with terminal or chronic conditions, requiring significant practice adaptations and including numerous legal, social, ethical, moral implications, the health research community has been working in consultation with clinicians, service providers and governments to generate knowledge that ensures safe, ethical and equitable practice in this regard.
Author Interviews, Heart Disease, Lipids / 08.01.2026

[caption id="attachment_71964" align="alignleft" width="256"]Ask T. Nordestgaard, MD PhDPostdoctoral research fellow Division of Preventive Medicine Brigham and Women's Hospital Boston, MA 02215 Dr. Nordestgaard[/caption] MedicalResearch.com Interview with: Ask T. Nordestgaard, MD PhD Postdoctoral research fellow Division of Preventive Medicine Brigham and Women's Hospital Boston, MA 02215   MedicalResearch.com: What is the background for this study? Response: Elevated Lp(a) is associated with high risk of CVD in multiple cohorts. We have recently shown that Lp(a) in the highest quintile is associated with 30-year risk of CVD; however, among healthy individuals, these results may be driven only by those with very extreme Lp(a) levels (e.g., above the 99th percentile). Therefore, in this follow-up study, we examined associations between various clinical thresholds of Lp(a) and CVD across 30 years of follow-up among apparently healthy women.
Author Interviews, Environmental Risks / 02.01.2026

MedicalResearch.com Interview with: [caption id="attachment_71921" align="alignleft" width="150"]Wenhui Qiu, PhDAssociate Professor School of Environmental Science and Engineering Southern University of Science and Technology Shenzhen, China Dr. Wenhui Qiu[/caption] Wenhui Qiu, PhD Associate Professor School of Environmental Science and Engineering Southern University of Science and Technology Shenzhen, China [caption id="attachment_71922" align="alignleft" width="121"] Dr. Chunmiao Zheng[/caption] Chunmiao Zheng, PhD AGU Fellow, Chair Professor Hydrologic Science Eastern Institute of Technology Ningbo, China       MedicalResearch.com: What is the background for this study? Response: Per- and polyfluoroalkyl substances (PFAS) are a class of artificially synthesized chemicals widely used in industrial production and consumer goods manufacturing. These substances are persistent in the environment, can accumulate through the food chain, and enter the human body and build up over time, posing a potential threat to health. As an important component of the global diet, marine fish may serve as a major source of PFAS intake for humans. However, the contribution of marine fish as a source of PFAS exposure and the associated health risks still lack systematic assessment on a global scale.
Alzheimer's - Dementia, Author Interviews, Case Western / 25.12.2025

MedicalResearch.com Interview with: [caption id="attachment_71888" align="alignleft" width="150"]Andrew A. Pieper M.D., Ph.D.Professor, Department of Psychiatry, School of Medicine Professor, Department of Neurosciences Professor, Department of Pathology Investigator, University Hospitals Harrington Discovery Institute, Harrington Discovery Institute Associate Director, Medical Scientist Training Program, School of Medicine Case Western Reserve University, University Hospitals Cleveland Medical Center, and at the Louis Stokes Cleveland VA Medical Center Dr. Pieper[/caption] Andrew A. Pieper M.D., Ph.D. Professor, Department of Psychiatry, School of Medicine Professor, Department of Neurosciences Professor, Department of Pathology Investigator, University Hospitals Harrington Discovery Institute, Harrington Discovery Institute Associate Director, Medical Scientist Training Program, School of Medicine Case Western Reserve University, University Hospitals Cleveland Medical Center, and at the Louis Stokes Cleveland VA Medical Center   MedicalResearch.com: What is the background for this study? Response: NAD+, a central cellular energy and signaling molecule, declines with age throughout the body, including the brain. When NAD+ falls below necessary levels, cells lose their ability to carry out essential maintenance and survival functions. We found that the NAD+ decline is more severe in brains from people with Alzheimer’s disease (AD) and in mouse models of AD, whereas brains of people with AD pathology but preserved cognition show gene-expression patterns consistent with maintained NAD+ homeostasis.
Author Interviews, Exercise - Fitness / 22.12.2025

[caption id="attachment_71865" align="aligncenter" width="500"]fitness-group-exercise.jpg Photo by cottonbro studio[/caption] You’ve been there before. You buy new workout clothes, set an ambitious goal, and start a new fitness routine with a burst of motivation. For the first week or two, you’re unstoppable. But then, life gets in the way. A long day at work makes the couch look more appealing than the treadmill. The thought of another repetitive, solo session at the gym feels more like a chore than a choice. Soon, you’re making excuses. The initial excitement fades, replaced by boredom or even a sense of intimidation as you navigate the equipment alone. This cycle is incredibly common, and it’s not a reflection of your willpower. The problem isn’t your motivation; it’s your method. The secret to long-term fitness consistency isn’t found in a new diet or a high-tech machine. It's found in the power of a supportive community. This article will explore the science-backed benefits of working out with others and show you why finding your tribe is the most important step you can take toward achieving your health goals.

Key Takeaways

  • Unbeatable Accountability: Working out with friends or in a group dramatically increases the likelihood you'll show up and stick with your fitness program long-term.
  • Enhanced Motivation & Performance: A social setting provides friendly competition and encouragement, pushing you to work harder and achieve better results than you would alone.
  • Increased Enjoyment: Group workouts are psychologically more rewarding and fun, transforming exercise from a tedious task into a positive social event you’ll look forward to.
  • The Right Environment is Key: A supportive, community-focused gym provides the structure and camaraderie needed to make social fitness a sustainable success.
Author Interviews, Technology / 22.12.2025

[caption id="attachment_71860" align="aligncenter" width="500"]Bozeman's Regulated Industries Photo by Kevin Ku[/caption] As a business owner in Bozeman's healthcare or financial sectors, you're an expert in your field. You navigate complex patient needs or intricate financial markets with skill. But alongside your core expertise comes a heavy burden: the non-negotiable, high-stakes world of IT compliance and data security. The regulations are dense, the threats are constant, and the penalties for a single misstep are severe. This reality leads to a critical question. How can you ensure your sensitive client data is protected, and your business remains compliant without an in-house IT security expert? It’s a challenge that keeps many local business owners up at night. This article is your answer. We will break down the specific risks you face, clarify the distinct advantages of local IT support, and provide a clear roadmap for protecting your business and your hard-earned reputation.

Key Takeaways

  • The financial and reputational costs of a data breach or compliance failure are devastatingly high, especially for healthcare and financial firms in Montana.
  • National, remote-only IT providers often lack the rapid, hands-on response and understanding of the local business environment that Bozeman companies need.
  • A local IT partner offers tangible advantages in regulatory familiarity, personalized strategy, and immediate on-site emergency support.
  • Key services like proactive network monitoring, robust data backup, and strategic compliance planning are non-negotiable for any business in a regulated industry.
Author Interviews, Surgical Research / 20.12.2025

Constructing or renovating an operating room is one of the most intricate projects in healthcare design. Every detail, from air circulation to technology integration, plays a critical role in maintaining safety and functionality. Yet the process extends far beyond mechanical systems and sterile finishes. It is about creating an environment where technology, people, and process work together with seamless precision.   The earliest stages of an operating room build begin long before construction starts. Successful projects start with understanding how surgical teams move, communicate, and interact with equipment. Layouts must support clear sightlines, efficient circulation, and ergonomic access to tools and supplies. Architects, clinicians, and engineers often collaborate through detailed simulations to ensure every inch of the space serves a purpose. When this planning is thorough, the final build supports not only compliance but also the daily rhythm of surgical teams.