Author Interviews, Biomarkers, Heart Disease / 18.07.2013

Dr Nicholas D Gollop BSc (Hons) MB BCh Norfolk and Norwich University Hospital, Norwich, NR4 7UY Norfolk, United KingdomInterview with: Dr Nicholas D Gollop BSc (Hons) MB BCh Norfolk and Norwich University Hospital, Norwich, NR4 7UY Norfolk, United Kingdom     MedicalResearch.com: What are the main findings of the study? We completed a best evidence topic in interventional cardiac surgery to investigate the significance of elevated markers of cardiac damage following percutaneous coronary intervention (PCI). We compared the clinical and prognostic relevance of the elevation of creatinine kinase-myocardial band (CK-MB) and cardiac troponin (cTn) levels during peri-procedural period and post-procedural period, respectively, following an emergency or elective PCI. We found in excess of 390 papers after a systematic literature search, of which 10 represented the best evidence to answer the clinical question. From the best evidence available we showed that the monitoring of cardiac biomarkers following PCI can provide important clinical information about the health of the myocardium, as well as prognostic information on short to mid-term outcomes of mortality up to 3 years. (more…)