Author Interviews, NEJM / 27.07.2013
Pulmonary Arterial Hypertension : New Potassium Channel as Genetic Cause
MedicalResearch.com Interview with:
Wendy Chung, MD PhD
Herbert Irving Associate Professor of Pediatrics and Medicine
Director of Clinical Genetics
Columbia University
1150 St. Nicholas Avenue, Room 620
New York, NY 10032
MedicalResearch.com: What are the main findings of the study?
Dr. Chung: We have identified a potassium channel as a new genetic cause of pulmonary hypertension and demonstrated it as a cause of pulmonary hypertension in patients with familial disease and sporadic disease without a family history of pulmonary hypertension. In vitro we were able to rescue several of the mutations pharmacologically. This potassium channel now provides a new target for treatment for pulmonary hypertension.
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