Author Interviews, Nature, Stem Cells / 05.09.2022
Scientists Develop Mouse Embryo from Stem Cells, Including Brain and Beating Heart
MedicalResearch.com Interview with:
[caption id="attachment_59492" align="alignleft" width="150"]
Dr. Amadei[/caption]
Gianluca Amadei PhD
Post-Doctoral Fellow
University of Cambridge, UK
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: The background of this study is that we tried to build a structure that looks and develops like a real mouse embryo using different kinds of mouse stem cells.
The main findings are that the resulting structures develop the entire embryonic body axis and the extraembryonic tissues that are required to support embryonic development. Our structures develop to a stage comparable to 8.5 days of embryonic development of the natural mouse embryos and have a brain and neural tube, a beating heart-like structure, gut and primordial germ cells.
Dr. Amadei[/caption]
Gianluca Amadei PhD
Post-Doctoral Fellow
University of Cambridge, UK
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: The background of this study is that we tried to build a structure that looks and develops like a real mouse embryo using different kinds of mouse stem cells.
The main findings are that the resulting structures develop the entire embryonic body axis and the extraembryonic tissues that are required to support embryonic development. Our structures develop to a stage comparable to 8.5 days of embryonic development of the natural mouse embryos and have a brain and neural tube, a beating heart-like structure, gut and primordial germ cells.
