Author Interviews, JAMA, Psychological Science / 18.12.2017
Deep Brain Stimulation Helpful For Some Visual Hallucinations
MedicalResearch.com Interview with:
Thomas Foltynie MD PhD
Senior Lecturer and Honorary Consultant Neurologist
Unit of Functional Neurosurgery Institute of Neurology and
National Hospital for Neurology and Neurosurgery
University College London
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Stimulation of the Nucleus Basalis of Meynert can enhance cholinergic innervation of the cortex in animal models and has been previously reported to have beneficial cognitive effects in a single patient with Parkinson’s Disease dementia.
In this double blind crossover trial, six patients with Parkinson’s Disease underwent low frequency stimulation to the NBM bilaterally. While there were no consistent objective improvements in cognitive performance, there was a marked reduction in visual hallucinations in two of the participants. .
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