Author Interviews, Infections, OBGYNE / 04.12.2019
Study Refutes “Sterile Womb Dogma”: How the Cold Virus Can Spread to Fetus from Mother
MedicalResearch.com Interview with:
Giovanni Piedimonte, MD, FAAP, FCCP
Vice President for Research
Institutional Official
Professor of Pediatrics
Tulane University
MedicalResearch.com: What is the background for this study?
Response: We have been testing the hypothesis that, when a pregnant woman catches a common cold with a virus called respiratory syncytial virus (RSV), viral particles can spread from the mother’s respiratory tract to the unborn child via the placenta. Preliminary data in animal models suggest that this is possible, and might cause changes in lung growth predisposing the offspring to develop asthma after birth. Recently, also human data have supported this theory.
However, an essential step to conclusively demonstrate vertical transmission of respiratory viruses was the confirmation that human placentas can be infected and allow the transmission of such germs, which is the main finding of this study. (more…)