Aging, Supplements / 18.11.2024

Editor’s note: NADH is not the same as  niacin, niacinamide, or nicotinamide riboside.  Please discuss the use of NAD⁺ with your health care provider before use and if you are taking long term.  NAD⁺ supplements are not FDA tested and may vary between formulations.  There are no studies of NAD⁺ in children, pregnancy, breast feeding or those planning to become pregnant. The efficacy and long term safety of NAD⁺ has not been definitively determined. Products discussed have not been independently verified. In the ever-growing world of longevity research, one name that has gained significant attention is Nicotine Mononucleotide (NMN). This compound, once considered just a minor player in biochemistry, has become the focal point of discussions about aging, healthspan, and the potential to reverse age-related cellular decline. Dr. David Sinclair, a leading scientist in the field of aging and professor at Harvard Medical School, debuted NMN to a wider audience during his appearance on the Joe Rogan Experience podcast. Since then, interest in NMN has skyrocketed, with many wondering: Can this molecule really slow down or even reverse the aging process? In this article, we’ll delve into the science behind NMN, explore its potential as an anti-aging molecule, and discuss how you can incorporate it into your daily routine.

What is NMN?

Nicotinamide Mononucleotide (NMN) is a naturally occurring compound found in all living cells. It is a derivative of niacin (Vitamin B3) and plays a crucial role in the production of Nicotinamide Adenine Dinucleotide (NAD+), a coenzyme that is essential for life. NAD+ is involved in numerous fundamental cellular processes, including energy production, DNA repair, and maintenance of cellular health. However, as we age, our NAD+ levels decline, leading to a range of cellular dysfunctions that contribute to aging and age-related diseases. Dr. David Sinclair, in his extensive research on aging, discovered that boosting NAD+ levels could have profound implications for slowing down the aging process. Since NMN is a direct precursor to NAD+, it is believed that supplementing with NMN could effectively restore NAD+ levels and support the body’s natural repair mechanisms. (more…)