MedicalResearch.com Interview with: Michael O'Rand, PhD Retired professor of cell biology and physiology in the University of North Carolina at Chapel Hill School of Medicine, and president/CEO of Eppin Pharma, Inc MedicalResearch.com: What is the background for this study? What are the main findings? Response: My lab at the UNC School of Medicine discovered the protein Eppin in 2004. It coats the sperm cell. Through our subsequent research, we learned it is essential for sperm protection in the female. We thought it could make an excellent target for a male contraceptive. Subsequently we developed a compound called EP055 that would bind to Eppin and as a result stop sperm from swimming. In our latest study published in PLOS One, we show that EP055 substantially limits sperm motility in non-human primates. And we showed the effect of EP055 is temporary, which would make it a good contraceptive. (more…)