Author Interviews, Diabetes, Kidney Disease, Nature, Semaglutide / 31.10.2024
Study Finds Semaglutide Reduced Kidney Inflammation and Blood Pressure in Obese Patients Without Diabetes
MedicalResearch.com Interview on publication of:
Prof. dr. H.J. (Hiddo) Lambers Heerspink
Clinical Pharmacologist
Faculty of Medical Sciences
University of Groningen
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: The diabetes drug semaglutide, also known as Ozempic, has a positive effect for patients with chronic kidney damage and obesity. The amount of protein in their urine decreased, as did the degree of inflammation of their kidneys and their blood pressure.
Hiddo L. Heerspink got the idea for this study at the beginning of the corona pandemic. Earlier, he had discovered that another class of drugs against diabetes-2, the so-called SGLT2 inhibitors also appeared to work well for patients with chronic kidney damage without diabetes. He therefore wanted to investigate whether semaglutide would also work positively for patients with chronic kidney disease and obesity.
(more…)